Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides
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Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides. / Larsen, Anders Foller; Ulven, Trond.
In: Organic Letters, Vol. 13, No. 13, 2011, p. 3546-3548.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides
AU - Larsen, Anders Foller
AU - Ulven, Trond
PY - 2011
Y1 - 2011
N2 - A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.
AB - A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.
U2 - 10.1021/ol201321z
DO - 10.1021/ol201321z
M3 - Journal article
VL - 13
SP - 3546
EP - 3548
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 13
ER -
ID: 189161120