Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa

Research output: Contribution to journalJournal articleResearchpeer-review

  • Marianne Molander Schmidt
  • Line Hagner Nielsen
  • Søren Vinter Søgaard
  • Stærk, Dan
  • Rønsted, Nina
  • Drissa Diallo
  • Chifundera Kusamba Zacharie
  • Johannes van Staden
  • Anna Jäger
ETHNOPHARMACOLOGICAL RELEVANCE:
Snakebite envenomation, every year, causes estimated 5-10,000 mortalities and results in more than 5-15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional medicine systems contain compounds against the necrosis-inducing enzymes of snake venom.
Original languageEnglish
JournalJournal of Ethnopharmacology
Volume157
Pages (from-to)171-180
Number of pages10
ISSN0378-8741
DOIs
Publication statusPublished - 2014

ID: 123611306