Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. / Lin, Xue; Li, Jian; Yin, Guangliang; Zhao, Qian; Elias, Daniel; Lykkesfeldt, Anne; Stenvang, Jan; Brünner, Nils; Wang, Jun; Yang, Huanming; Bolund, Lars; Ditzel, Henrik Jørn.

In: Breast cancer research : BCR, Vol. 15, No. 6, R119, 2013.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lin, X, Li, J, Yin, G, Zhao, Q, Elias, D, Lykkesfeldt, A, Stenvang, J, Brünner, N, Wang, J, Yang, H, Bolund, L & Ditzel, HJ 2013, 'Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties', Breast cancer research : BCR, vol. 15, no. 6, R119. https://doi.org/10.1186/bcr3588

APA

Lin, X., Li, J., Yin, G., Zhao, Q., Elias, D., Lykkesfeldt, A., Stenvang, J., Brünner, N., Wang, J., Yang, H., Bolund, L., & Ditzel, H. J. (2013). Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. Breast cancer research : BCR, 15(6), [R119]. https://doi.org/10.1186/bcr3588

Vancouver

Lin X, Li J, Yin G, Zhao Q, Elias D, Lykkesfeldt A et al. Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. Breast cancer research : BCR. 2013;15(6). R119. https://doi.org/10.1186/bcr3588

Author

Lin, Xue ; Li, Jian ; Yin, Guangliang ; Zhao, Qian ; Elias, Daniel ; Lykkesfeldt, Anne ; Stenvang, Jan ; Brünner, Nils ; Wang, Jun ; Yang, Huanming ; Bolund, Lars ; Ditzel, Henrik Jørn. / Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. In: Breast cancer research : BCR. 2013 ; Vol. 15, No. 6.

Bibtex

@article{9308e330daed464eb0754bd829ba0061,
title = "Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties",
abstract = "Development of resistance to tamoxifen is an important clinical issue in the treatment of breast cancer. Tamoxifen resistance may be the result of acquisition of epigenetic regulation within breast cancer cells, such as DNA methylation, resulting in changed mRNA expression of genes pivotal for estrogen-dependent growth. Alternatively, tamoxifen resistance may be due to selection of pre-existing resistant cells, or a combination of the two mechanisms.",
author = "Xue Lin and Jian Li and Guangliang Yin and Qian Zhao and Daniel Elias and Anne Lykkesfeldt and Jan Stenvang and Nils Br{\"u}nner and Jun Wang and Huanming Yang and Lars Bolund and Ditzel, {Henrik J{\o}rn}",
year = "2013",
doi = "10.1186/bcr3588",
language = "English",
volume = "15",
journal = "Breast Cancer Research",
issn = "1465-5411",
publisher = "BioMed Central Ltd.",
number = "6",

}

RIS

TY - JOUR

T1 - Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

AU - Lin, Xue

AU - Li, Jian

AU - Yin, Guangliang

AU - Zhao, Qian

AU - Elias, Daniel

AU - Lykkesfeldt, Anne

AU - Stenvang, Jan

AU - Brünner, Nils

AU - Wang, Jun

AU - Yang, Huanming

AU - Bolund, Lars

AU - Ditzel, Henrik Jørn

PY - 2013

Y1 - 2013

N2 - Development of resistance to tamoxifen is an important clinical issue in the treatment of breast cancer. Tamoxifen resistance may be the result of acquisition of epigenetic regulation within breast cancer cells, such as DNA methylation, resulting in changed mRNA expression of genes pivotal for estrogen-dependent growth. Alternatively, tamoxifen resistance may be due to selection of pre-existing resistant cells, or a combination of the two mechanisms.

AB - Development of resistance to tamoxifen is an important clinical issue in the treatment of breast cancer. Tamoxifen resistance may be the result of acquisition of epigenetic regulation within breast cancer cells, such as DNA methylation, resulting in changed mRNA expression of genes pivotal for estrogen-dependent growth. Alternatively, tamoxifen resistance may be due to selection of pre-existing resistant cells, or a combination of the two mechanisms.

U2 - 10.1186/bcr3588

DO - 10.1186/bcr3588

M3 - Journal article

C2 - 24355041

VL - 15

JO - Breast Cancer Research

JF - Breast Cancer Research

SN - 1465-5411

IS - 6

M1 - R119

ER -

ID: 98037889