Macrocyclic G-quadruplex ligands

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Macrocyclic G-quadruplex ligands. / Nielsen, M C; Ulven, Trond.

In: Current Medicinal Chemistry, Vol. 17, No. 29, 01.01.2010, p. 3438-3448.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nielsen, MC & Ulven, T 2010, 'Macrocyclic G-quadruplex ligands', Current Medicinal Chemistry, vol. 17, no. 29, pp. 3438-3448.

APA

Nielsen, M. C., & Ulven, T. (2010). Macrocyclic G-quadruplex ligands. Current Medicinal Chemistry, 17(29), 3438-3448.

Vancouver

Nielsen MC, Ulven T. Macrocyclic G-quadruplex ligands. Current Medicinal Chemistry. 2010 Jan 1;17(29):3438-3448.

Author

Nielsen, M C ; Ulven, Trond. / Macrocyclic G-quadruplex ligands. In: Current Medicinal Chemistry. 2010 ; Vol. 17, No. 29. pp. 3438-3448.

Bibtex

@article{75e6f5bb71d94833bd39cd020b60fc5c,
title = "Macrocyclic G-quadruplex ligands",
abstract = "G-quadruplex stabilizing compounds have recently received increased interest due to their potential application as anticancer therapeutics. A significant number of structurally diverse G-quadruplex ligands have been developed. Some of the most potent and selective ligands currently known are macrocyclic structures which have been modeled after the natural product telomestatin or from porphyrin-based ligands discovered in the late 1990s. These two structural classes of G-quadruplex ligands are reviewed here with special attention to selectivity and structure-activity relationships, and with focus on the recent developments.",
author = "Nielsen, {M C} and Trond Ulven",
year = "2010",
month = jan,
day = "1",
language = "English",
volume = "17",
pages = "3438--3448",
journal = "Current Medicinal Chemistry",
issn = "0929-8673",
publisher = "Bentham Science Publishers",
number = "29",

}

RIS

TY - JOUR

T1 - Macrocyclic G-quadruplex ligands

AU - Nielsen, M C

AU - Ulven, Trond

PY - 2010/1/1

Y1 - 2010/1/1

N2 - G-quadruplex stabilizing compounds have recently received increased interest due to their potential application as anticancer therapeutics. A significant number of structurally diverse G-quadruplex ligands have been developed. Some of the most potent and selective ligands currently known are macrocyclic structures which have been modeled after the natural product telomestatin or from porphyrin-based ligands discovered in the late 1990s. These two structural classes of G-quadruplex ligands are reviewed here with special attention to selectivity and structure-activity relationships, and with focus on the recent developments.

AB - G-quadruplex stabilizing compounds have recently received increased interest due to their potential application as anticancer therapeutics. A significant number of structurally diverse G-quadruplex ligands have been developed. Some of the most potent and selective ligands currently known are macrocyclic structures which have been modeled after the natural product telomestatin or from porphyrin-based ligands discovered in the late 1990s. These two structural classes of G-quadruplex ligands are reviewed here with special attention to selectivity and structure-activity relationships, and with focus on the recent developments.

M3 - Journal article

VL - 17

SP - 3438

EP - 3448

JO - Current Medicinal Chemistry

JF - Current Medicinal Chemistry

SN - 0929-8673

IS - 29

ER -

ID: 189160689