Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. / Toft, B.S.; Hansen, Harald S.

In: B B A - Molecular and Cell Biology of Lipids, Vol. 574, No. 1, 27.07.1979, p. 33-38.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Toft, BS & Hansen, HS 1979, 'Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney', B B A - Molecular and Cell Biology of Lipids, vol. 574, no. 1, pp. 33-38.

APA

Toft, B. S., & Hansen, H. S. (1979). Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. B B A - Molecular and Cell Biology of Lipids, 574(1), 33-38.

Vancouver

Toft BS, Hansen HS. Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. B B A - Molecular and Cell Biology of Lipids. 1979 Jul 27;574(1):33-38.

Author

Toft, B.S. ; Hansen, Harald S. / Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. In: B B A - Molecular and Cell Biology of Lipids. 1979 ; Vol. 574, No. 1. pp. 33-38.

Bibtex

@article{e3ce2a06e5dd434ea2e4e72d722a27ab,
title = "Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney",
abstract = "Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.",
author = "B.S. Toft and Hansen, {Harald S.}",
year = "1979",
month = jul,
day = "27",
language = "English",
volume = "574",
pages = "33--38",
journal = "B B A - Molecular and Cell Biology of Lipids",
issn = "1388-1981",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney

AU - Toft, B.S.

AU - Hansen, Harald S.

PY - 1979/7/27

Y1 - 1979/7/27

N2 - Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.

AB - Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.

UR - http://www.scopus.com/inward/record.url?scp=0018654510&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0018654510

VL - 574

SP - 33

EP - 38

JO - B B A - Molecular and Cell Biology of Lipids

JF - B B A - Molecular and Cell Biology of Lipids

SN - 1388-1981

IS - 1

ER -

ID: 45562933