Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

Department of Drug Design and Pharmacology

Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

Research output: Contribution to journal › Journal article › Research › peer-review

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Sadia Asghar Butt
Lise V Søgaard
Jan H Ardenkjaer-Larsen
Mette H Lauritzen
Lars H Engelholm
Paulson, Olaf B.
Mirza, Osman Asghar
Susanne Holck
Peter Magnusson
Per Akeson

To use dynamic magnetic resonance spectroscopy (MRS) of hyperpolarized (13) C-pyruvate to follow the progress over time in vivo of breast cancer metabolism in the MMTV-PymT model, and to follow the response to the anti-estrogen drug tamoxifen.

Original language	English
Journal	Magnetic Resonance in Medicine
Volume	73
Pages (from-to)	51-58
Number of pages	8
ISSN	0740-3194
DOIs	https://doi.org/10.1002/mrm.25095
Publication status	Published - 16 Jan 2015

ID: 96233904