Pharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations
Research output: Contribution to journal › Journal article › Research › peer-review
GPRC6A is a novel member of family C of G protein-coupled receptors with so far unknown function. We have recently described both human and mouse GPRC6A as receptors for L-alpha-amino acids. To date, functional characterization of wild-type GPRC6A has been impaired by the lack of activity in quantitative functional assays. The aim of this study was thus to develop such an assay and extend the pharmacological characterization of GPRC6A.
| Original language | English |
|---|---|
| Journal | British Journal of Pharmacology |
| Volume | 150 |
| Issue number | 6 |
| Pages (from-to) | 798-807 |
| ISSN | 0007-1188 |
| DOIs | |
| Publication status | Published - 2007 |
- Animals, Arginine, Calcium, Cations, Divalent, Female, GTP-Binding Protein alpha Subunits, Humans, Inositol Phosphates, Kinetics, Lysine, Magnesium, Mice, Oocytes, Ornithine, Rats, Receptors, Amino Acid, Receptors, G-Protein-Coupled, Recombinant Proteins, Transfection, Xenopus laevis
Research areas
ID: 2403221