Risk of Type 1 Diabetes in Children Is Not Increased After SARS-CoV-2 Infection: A Nationwide Prospective Study in Denmark
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Risk of Type 1 Diabetes in Children Is Not Increased After SARS-CoV-2 Infection : A Nationwide Prospective Study in Denmark. / Noorzae, Rohina; Junker, Thor Grønborg; Hviid, Anders Peter; Wohlfahrt, Jan; Olsen, Sjurdur Frodi.
In: Diabetes Care, Vol. 46, No. 6, 2023, p. 1261-1264.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Risk of Type 1 Diabetes in Children Is Not Increased After SARS-CoV-2 Infection
T2 - A Nationwide Prospective Study in Denmark
AU - Noorzae, Rohina
AU - Junker, Thor Grønborg
AU - Hviid, Anders Peter
AU - Wohlfahrt, Jan
AU - Olsen, Sjurdur Frodi
N1 - Publisher Copyright: © 2023 by the American Diabetes Association.
PY - 2023
Y1 - 2023
N2 - OBJECTIVE: It has been hypothesized that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children can increase risk of developing type 1 diabetes. RESEARCH DESIGN AND METHODS: We undertook a prospective, register-based analysis of children in Denmark by investigating the association between SARS-CoV-2 infection and subsequent risk of type 1 diabetes. During the pandemic, Denmark had one of the highest test rates per capita in the world, and 90% of all Danish children were tested. RESULTS: Compared with children with a history of only negative SARS-CoV-2 tests, we did not observe a higher risk of first-time diagnosis of type 1 diabetes in children 30 days or more after a positive SARS-CoV-2 test (hazard ratio 0.85; 95% CI 0.70-1.04). CONCLUSIONS: Our data do not support that SARS-CoV-2 infection is associated with type 1 diabetes or that type 1 diabetes should be a special focus after a SARS-CoV-2 infection in children.
AB - OBJECTIVE: It has been hypothesized that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children can increase risk of developing type 1 diabetes. RESEARCH DESIGN AND METHODS: We undertook a prospective, register-based analysis of children in Denmark by investigating the association between SARS-CoV-2 infection and subsequent risk of type 1 diabetes. During the pandemic, Denmark had one of the highest test rates per capita in the world, and 90% of all Danish children were tested. RESULTS: Compared with children with a history of only negative SARS-CoV-2 tests, we did not observe a higher risk of first-time diagnosis of type 1 diabetes in children 30 days or more after a positive SARS-CoV-2 test (hazard ratio 0.85; 95% CI 0.70-1.04). CONCLUSIONS: Our data do not support that SARS-CoV-2 infection is associated with type 1 diabetes or that type 1 diabetes should be a special focus after a SARS-CoV-2 infection in children.
U2 - 10.2337/dc22-2351
DO - 10.2337/dc22-2351
M3 - Journal article
C2 - 37058353
AN - SCOPUS:85160023771
VL - 46
SP - 1261
EP - 1264
JO - Diabetes Care
JF - Diabetes Care
SN - 1935-5548
IS - 6
ER -
ID: 361075425