Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A
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Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A. / Franzyk, Henrik; Jensen, Søren Rosendal; Olsen, Carl Erik; Rasmussen, Jon Holbech.
In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 21, No. 1, 2002, p. 23-43.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A
AU - Franzyk, Henrik
AU - Jensen, Søren Rosendal
AU - Olsen, Carl Erik
AU - Rasmussen, Jon Holbech
PY - 2002
Y1 - 2002
N2 - Two enantiomerically pure hydroxymethyl substituted cyclopentene nucleoside analogues (42 and 53) related to carbovir and neplanocin A, respectively, were prepared from the chiral pool of iridoid glucosides. In addition two saturated hydroxymethylated analogues (44 and 45) were obtained from a protected intermediate.
AB - Two enantiomerically pure hydroxymethyl substituted cyclopentene nucleoside analogues (42 and 53) related to carbovir and neplanocin A, respectively, were prepared from the chiral pool of iridoid glucosides. In addition two saturated hydroxymethylated analogues (44 and 45) were obtained from a protected intermediate.
KW - Adenosine
KW - Dideoxynucleosides
KW - Nucleosides
U2 - 10.1081/NCN-120006528
DO - 10.1081/NCN-120006528
M3 - Journal article
C2 - 11991147
VL - 21
SP - 23
EP - 43
JO - Nucleosides, Nucleotides and Nucleic Acids
JF - Nucleosides, Nucleotides and Nucleic Acids
SN - 1525-7770
IS - 1
ER -
ID: 47258155