The endocannabinoid system and its relevance for nutrition

Research output: Contribution to journal › Journal article › Research › peer-review

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The endocannabinoid system and its relevance for nutrition. / Maccarrone, Mauro; Gasperi, Valeria; Catani, Maria Valeria; Diep, Thi Ai; Dainese, Enrico; Hansen, Harald S.; Avigliano, Luciana.

In: Annual Review of Nutrition, Vol. 30, 21.08.2010, p. 423-40.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Maccarrone, M, Gasperi, V, Catani, MV, Diep, TA, Dainese, E, Hansen, HS & Avigliano, L 2010, 'The endocannabinoid system and its relevance for nutrition', Annual Review of Nutrition, vol. 30, pp. 423-40. https://doi.org/10.1146/annurev.nutr.012809.104701

APA

Maccarrone, M., Gasperi, V., Catani, M. V., Diep, T. A., Dainese, E., Hansen, H. S., & Avigliano, L. (2010). The endocannabinoid system and its relevance for nutrition. Annual Review of Nutrition, 30, 423-40. https://doi.org/10.1146/annurev.nutr.012809.104701

Vancouver

Maccarrone M, Gasperi V, Catani MV, Diep TA, Dainese E, Hansen HS et al. The endocannabinoid system and its relevance for nutrition. Annual Review of Nutrition. 2010 Aug 21;30:423-40. https://doi.org/10.1146/annurev.nutr.012809.104701

Author

Maccarrone, Mauro ; Gasperi, Valeria ; Catani, Maria Valeria ; Diep, Thi Ai ; Dainese, Enrico ; Hansen, Harald S. ; Avigliano, Luciana. / The endocannabinoid system and its relevance for nutrition. In: Annual Review of Nutrition. 2010 ; Vol. 30. pp. 423-40.

Bibtex

@article{bcc64333f4954741bdcd9899ca3454fc,
title = "The endocannabinoid system and its relevance for nutrition",
abstract = "Endocannabinoids bind to cannabinoid, vanilloid, and peroxisome proliferator-activated receptors. The biological actions of these polyunsaturated lipids are controlled by key agents responsible for their synthesis, transport and degradation, which together form an endocannabinoid system (ECS). In the past few years, evidence has been accumulated for a role of the ECS in regulating food intake and energy balance, both centrally and peripherally. In addition, up-regulation of the ECS in the gastrointestinal tract has a potential impact on inflammatory bowel diseases. In this review, the main features of the ECS are summarized in order to put in better focus our current knowledge of the nutritional relevance of endocannabinoid signaling and of its role in obesity, cardiovascular pathologies, and gastrointestinal diseases. The central and peripheral pathways that underlie these effects are discussed, as well as the possible exploitation of ECS components as novel drug targets for therapeutic intervention in eating disorders.",
keywords = "Cardiovascular Diseases, Diet, Endocannabinoids, Energy Metabolism, Gastrointestinal Diseases, Humans, Obesity, Receptors, Cannabinoid, Signal Transduction",
author = "Mauro Maccarrone and Valeria Gasperi and Catani, {Maria Valeria} and Diep, {Thi Ai} and Enrico Dainese and Hansen, {Harald S.} and Luciana Avigliano",
year = "2010",
month = aug,
day = "21",
doi = "10.1146/annurev.nutr.012809.104701",
language = "English",
volume = "30",
pages = "423--40",
journal = "Annual Review of Nutrition",
issn = "0199-9885",
publisher = "Annual Reviews, inc.",

}

RIS

TY - JOUR

T1 - The endocannabinoid system and its relevance for nutrition

AU - Maccarrone, Mauro

AU - Gasperi, Valeria

AU - Catani, Maria Valeria

AU - Diep, Thi Ai

AU - Dainese, Enrico

AU - Hansen, Harald S.

AU - Avigliano, Luciana

PY - 2010/8/21

Y1 - 2010/8/21

N2 - Endocannabinoids bind to cannabinoid, vanilloid, and peroxisome proliferator-activated receptors. The biological actions of these polyunsaturated lipids are controlled by key agents responsible for their synthesis, transport and degradation, which together form an endocannabinoid system (ECS). In the past few years, evidence has been accumulated for a role of the ECS in regulating food intake and energy balance, both centrally and peripherally. In addition, up-regulation of the ECS in the gastrointestinal tract has a potential impact on inflammatory bowel diseases. In this review, the main features of the ECS are summarized in order to put in better focus our current knowledge of the nutritional relevance of endocannabinoid signaling and of its role in obesity, cardiovascular pathologies, and gastrointestinal diseases. The central and peripheral pathways that underlie these effects are discussed, as well as the possible exploitation of ECS components as novel drug targets for therapeutic intervention in eating disorders.

AB - Endocannabinoids bind to cannabinoid, vanilloid, and peroxisome proliferator-activated receptors. The biological actions of these polyunsaturated lipids are controlled by key agents responsible for their synthesis, transport and degradation, which together form an endocannabinoid system (ECS). In the past few years, evidence has been accumulated for a role of the ECS in regulating food intake and energy balance, both centrally and peripherally. In addition, up-regulation of the ECS in the gastrointestinal tract has a potential impact on inflammatory bowel diseases. In this review, the main features of the ECS are summarized in order to put in better focus our current knowledge of the nutritional relevance of endocannabinoid signaling and of its role in obesity, cardiovascular pathologies, and gastrointestinal diseases. The central and peripheral pathways that underlie these effects are discussed, as well as the possible exploitation of ECS components as novel drug targets for therapeutic intervention in eating disorders.

KW - Cardiovascular Diseases

KW - Diet

KW - Endocannabinoids

KW - Energy Metabolism

KW - Gastrointestinal Diseases

KW - Humans

KW - Obesity

KW - Receptors, Cannabinoid

KW - Signal Transduction

U2 - 10.1146/annurev.nutr.012809.104701

DO - 10.1146/annurev.nutr.012809.104701

M3 - Journal article

C2 - 20645854

VL - 30

SP - 423

EP - 440

JO - Annual Review of Nutrition

JF - Annual Review of Nutrition

SN - 0199-9885

ER -

ID: 33221205