The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

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The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. / Bjarnadóttir, Thóra K; Fredriksson, Robert; Höglund, Pär J; Gloriam, David E.; Lagerström, Malin C; Schiöth, Helgi B.

In: Genomics, Vol. 84, No. 1, 07.2004, p. 23-33.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bjarnadóttir, TK, Fredriksson, R, Höglund, PJ, Gloriam, DE, Lagerström, MC & Schiöth, HB 2004, 'The human and mouse repertoire of the adhesion family of G-protein-coupled receptors', Genomics, vol. 84, no. 1, pp. 23-33. https://doi.org/10.1016/j.ygeno.2003.12.004

APA

Bjarnadóttir, T. K., Fredriksson, R., Höglund, P. J., Gloriam, D. E., Lagerström, M. C., & Schiöth, H. B. (2004). The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics, 84(1), 23-33. https://doi.org/10.1016/j.ygeno.2003.12.004

Vancouver

Bjarnadóttir TK, Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB. The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics. 2004 Jul;84(1):23-33. https://doi.org/10.1016/j.ygeno.2003.12.004

Author

Bjarnadóttir, Thóra K ; Fredriksson, Robert ; Höglund, Pär J ; Gloriam, David E. ; Lagerström, Malin C ; Schiöth, Helgi B. / The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. In: Genomics. 2004 ; Vol. 84, No. 1. pp. 23-33.

Bibtex

@article{d07c50fd9d8c4699a7255f72f195b049,
title = "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors",
abstract = "The adhesion G-protein-coupled receptors (GPCRs) (also termed LN-7TM or EGF-7TM receptors) are membrane-bound proteins with long N-termini containing multiple domains. Here, 2 new human adhesion-GPCRs, termed GPR133 and GPR144, have been found by searches done in the human genome databases. Both GPR133 and GPR144 have a GPS domain in their N-termini, while GPR144 also has a pentraxin domain. The phylogenetic analyses of the 2 new human receptors show that they group together without close relationship to the other adhesion-GPCRs. In addition to the human genes, mouse orthologues to those 2 and 15 other mouse orthologues to human were identified (GPR110, GPR111, GPR112, GPR113, GPR114, GPR115, GPR116, GPR123, GPR124, GPR125, GPR126, GPR128, LEC1, LEC2, and LEC3). Currently the total number of human adhesion-GPCRs is 33. The mouse and human sequences show a clear one-to-one relationship, with the exception of EMR2 and EMR3, which do not seem to have orthologues in mouse. EST expression charts for the entire repertoire of adhesion-GPCRs in human and mouse were established. Over 1600 ESTs were found for these receptors, showing widespread distribution in both central and peripheral tissues. The expression patterns are highly variable between different receptors, indicating that they participate in a number of physiological processes.",
author = "Bjarnad{\'o}ttir, {Th{\'o}ra K} and Robert Fredriksson and H{\"o}glund, {P{\"a}r J} and Gloriam, {David E.} and Lagerstr{\"o}m, {Malin C} and Schi{\"o}th, {Helgi B}",
note = "Copyright 2003 Elsevier Inc.",
year = "2004",
month = jul,
doi = "10.1016/j.ygeno.2003.12.004",
language = "English",
volume = "84",
pages = "23--33",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press",
number = "1",

}

RIS

TY - JOUR

T1 - The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

AU - Bjarnadóttir, Thóra K

AU - Fredriksson, Robert

AU - Höglund, Pär J

AU - Gloriam, David E.

AU - Lagerström, Malin C

AU - Schiöth, Helgi B

N1 - Copyright 2003 Elsevier Inc.

PY - 2004/7

Y1 - 2004/7

N2 - The adhesion G-protein-coupled receptors (GPCRs) (also termed LN-7TM or EGF-7TM receptors) are membrane-bound proteins with long N-termini containing multiple domains. Here, 2 new human adhesion-GPCRs, termed GPR133 and GPR144, have been found by searches done in the human genome databases. Both GPR133 and GPR144 have a GPS domain in their N-termini, while GPR144 also has a pentraxin domain. The phylogenetic analyses of the 2 new human receptors show that they group together without close relationship to the other adhesion-GPCRs. In addition to the human genes, mouse orthologues to those 2 and 15 other mouse orthologues to human were identified (GPR110, GPR111, GPR112, GPR113, GPR114, GPR115, GPR116, GPR123, GPR124, GPR125, GPR126, GPR128, LEC1, LEC2, and LEC3). Currently the total number of human adhesion-GPCRs is 33. The mouse and human sequences show a clear one-to-one relationship, with the exception of EMR2 and EMR3, which do not seem to have orthologues in mouse. EST expression charts for the entire repertoire of adhesion-GPCRs in human and mouse were established. Over 1600 ESTs were found for these receptors, showing widespread distribution in both central and peripheral tissues. The expression patterns are highly variable between different receptors, indicating that they participate in a number of physiological processes.

AB - The adhesion G-protein-coupled receptors (GPCRs) (also termed LN-7TM or EGF-7TM receptors) are membrane-bound proteins with long N-termini containing multiple domains. Here, 2 new human adhesion-GPCRs, termed GPR133 and GPR144, have been found by searches done in the human genome databases. Both GPR133 and GPR144 have a GPS domain in their N-termini, while GPR144 also has a pentraxin domain. The phylogenetic analyses of the 2 new human receptors show that they group together without close relationship to the other adhesion-GPCRs. In addition to the human genes, mouse orthologues to those 2 and 15 other mouse orthologues to human were identified (GPR110, GPR111, GPR112, GPR113, GPR114, GPR115, GPR116, GPR123, GPR124, GPR125, GPR126, GPR128, LEC1, LEC2, and LEC3). Currently the total number of human adhesion-GPCRs is 33. The mouse and human sequences show a clear one-to-one relationship, with the exception of EMR2 and EMR3, which do not seem to have orthologues in mouse. EST expression charts for the entire repertoire of adhesion-GPCRs in human and mouse were established. Over 1600 ESTs were found for these receptors, showing widespread distribution in both central and peripheral tissues. The expression patterns are highly variable between different receptors, indicating that they participate in a number of physiological processes.

U2 - 10.1016/j.ygeno.2003.12.004

DO - 10.1016/j.ygeno.2003.12.004

M3 - Journal article

C2 - 15203201

VL - 84

SP - 23

EP - 33

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 1

ER -

ID: 45811714