Rasmus Prætorius Clausen

Rasmus Prætorius Clausen

Professor

ORCID: 0000-0001-9466-9431

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  1. Published

    Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors

    Jørgensen, Charlotte Grube, Bräuner, Hans, Nielsen, Birgitte, Kehler, J., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl & Madsen, Ulf, 2007, In: Bioorganic & Medicinal Chemistry. 15, 10, p. 3524-3538

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Novel Approach toward 3,3-Difluoropiperidines from Easily Available Starting Materials and Synthesis of a New Phosphodiesterase Inhibitor

    Giacoboni, J., Clausen, Rasmus Prætorius & Marigo, M., Dec 2016, In: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 27, 20, p. 2803-2806 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Novel cyclic gamma-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain

    Wellendorph, Petrine, Høg, S., Greenwood, J. R., de Lichtenberg, A., Nielsen, Birgitte, Frølund, Bente, Brehm, L., Clausen, Rasmus Prætorius & Bräuner, Hans, Oct 2005, In: Journal of Pharmacology and Experimental Therapeutics. 315, 1, p. 346-51

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies

    Høg, S., Wellendorph, Petrine, Nielsen, Birgitte, Frydenvang, Karla Andrea, Dahl, I. F., Bräuner, Hans, Brehm, L., Frølund, Bente & Clausen, Rasmus Prætorius, 2008, In: Journal of Medicinal Chemistry. 51, 24, p. 8088-8095

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Novel radioiodinated γ-hydroxybutyric acid analogues for radiolabeling and photolinking of high-affinity γ-hydroxybutyric acid binding sites

    Wellendorph, Petrine, Høg, S., Sabbatini, P., Pedersen, M. H. F., Martiny, L., Knudsen, Gitte Moos, Frølund, Bente, Clausen, Rasmus Prætorius & Bräuner, Hans, 2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 2, p. 458-464

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Ny bioisoster kan skabe nye lægemidler

    Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2004, In: Lægemiddelforskning. 2004, p. 16-17

    Research output: Contribution to journal › Journal article › Communication

  7. Published

    Nye NMDA-receptor-ligander til udforskning af hjernen

    Clausen, Rasmus Prætorius, Risgaard, R., Nielsen, S. D., Kristensen, Jesper Langgaard & Hansen, K. B., 2010, In: Dansk Kemi. 91, 6/7, p. 21-23

    Research output: Contribution to journal › Journal article › Communication

  8. Published

    Opioid and cannabinoid receptors

    Clausen, Rasmus Prætorius & Hansen, Harald S., 2016, Textbook of drug design and discovery. 5. ed. CRC Press, p. 329-346

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  9. Published

    Opioid and cannabinoid receptors

    Clausen, Rasmus Prætorius & Hansen, Harald S., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 313-328

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  10. Published

    Organic chemistry at the interface to biology

    Clausen, Rasmus Prætorius, May 2006, In: ChemBioChem. 7, 5, p. 845-849

    Research output: Contribution to journal › Literature review › Research

  11. Published

    Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes

    El-Chami, C., Foster, A. R., Johnson, C., Clausen, Rasmus Prætorius, Cornwell, P., Haslam, I. S., Steward, M. C., Watson, R. E. B., Young, H. S. & O'Neill, C. A., 2021, In: British Journal of Dermatology. 184, 3, p. 482-494

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    P2X7 receptor-mediated analgesia in cancer-induced bone pain

    Falk, S., D. Schwab, S., Frøsig-Jørgensen, M., Clausen, Rasmus Prætorius, Dickenson, A. & Heegaard, Anne-Marie, 13 Feb 2015, In: Neuroscience. 291, p. 93–105 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Partial agonists and subunit selectivity at NMDA receptors

    Risgaard, R., Hansen, K. B. & Clausen, Rasmus Prætorius, 17 Dec 2010, In: Chemistry: A European Journal. 16, 47, p. 13910-13918

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects

    Lie, M. E. K., Kickinger, S., Skovgaard-Petersen, J., Ecker, G. F., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Wellendorph, Petrine, 2020, In: Neurochemical Research. 45, p. 1551–1565

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

    Al-Khawaja, A. M. A., Petersen, J. G., Damgaard, M., Jensen, M. H., Vogensen, S. B., Lie, M. E. K., Kragholm, B., Bräuner, Hans, Clausen, Rasmus Prætorius, Frølund, Bente & Wellendorph, Petrine, 23 May 2014, In: Neurochemical Research. 39, 10, p. 1988-1996 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Pharmacological characterisation of biarylisopropylalsulphonamide AMPA-R potentiators

    Pickering, Darryl S, Sanz, C., Harpsøe, Kasper, Clausen, Rasmus Prætorius, Sauerberg, P., Liljefors, T., Madsen, Ulf & Kaae, B. H., 2007, In: Journal of Neurochemistry. 102 (suppl. 1), 41

    Research output: Contribution to journal › Conference abstract in journal › Research

  17. Published

    Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Clausen, Rasmus Prætorius, Madsen, Ulf, Pedersen, L., Jimenez, H. N., Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, 2012, In: Molecular Pharmacology. 82, 5, p. 929-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Pharmacological manipulation of extrasynaptic GABA transporters: implications for epilepsy management

    Madsen, K. K., Ebert, B., Larsson, O. M., Clausen, Rasmus Prætorius, Schousboe, Arne & White, H. S., 2008, In: Epilepsia. Suppl. 7, p. 347

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

    Kristensen, Anders Skov, Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pøhlsgaard, J., Clausen, Rasmus Prætorius, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., Feb 2016, In: Molecular Pharmacology. 89, 2, p. 253-262 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Positive allosteric modulation of AMPA receptors differentially modulates the behavioural effects of citalopram in mouse models of antidepressant and anxiolytic action

    Fitzpatrick, C. M., Larsen, M., Madsen, L., Pickering, Darryl S, Clausen, Rasmus Prætorius & Andreasen T., Jesper, 26 Jun 2016, In: Behavioural Pharmacology. 27, 6, p. 549-555 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, B., Helgstrand, C., Andersson, J. L., Leurs, U., Cloos, P. A. C., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In: P L o S One. 8, 7, p. e67653

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry

    Fjelbye, K., Marigo, M., Clausen, Rasmus Prætorius & Juhl, K., 2017, In: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 28, 2, p. 231-234 4 p., st-2016-b0534-l.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites

    Jensen, C. H., Hansen, H. D., Bay, T., Vogensen, S. B., Lehel, S., Thiesen, L., Bundgaard, C., Clausen, Rasmus Prætorius, Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, 18 Jan 2017, In: A C S Chemical Neuroscience. 8, 1, p. 22-27 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    Ring opening of pymisyl-protected aziridines with organocuprates

    Bornholdt, J., Felding, J., Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 2010, In: Chemistry: A European Journal. 16, 41, p. 12474-12480

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

    Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In: Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1302218