Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry
Research output: Contribution to journal › Review › Research › peer-review
A series of novel N-Bn-protected spirocyclic β-proline esters were prepared using [3+2] cycloaddition and subsequently converted into their corresponding aldehydes. In addition, two novel N-Cbz-protected spirocyclic β-proline esters were prepared using intramolecular cyclization starting from simple precursors.
| Original language | English |
|---|---|
| Article number | st-2016-b0534-l |
| Journal | SYNLETT: Accounts and Rapid Communications in Chemical Synthesis |
| Volume | 28 |
| Issue number | 2 |
| Pages (from-to) | 231-234 |
| Number of pages | 4 |
| ISSN | 0936-5214 |
| DOIs | |
| Publication status | Published - 2017 |
- 1,3-dipolar cycloaddition, intramolecular cyclization, oxetanes, spirocycles, β-proline esters
Research areas
ID: 176009623