Christian Adam Olsen

Christian Adam Olsen

Professor

ORCID: 0000-0002-2953-8942

Publication year:
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51 - 75 out of 113Page size: 25
  1. 2016
  2. Published

    Innovative Strategies for Selective Inhibition of Histone Deacetylases

    Maolanon, A. R., Madsen, A. S. & Olsen, Christian Adam, 21 Jul 2016, In: Cell Chemical Biology. 23, 7, p. 759-768 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Optoepigenetics: An acetylation photoswitch

    Madsen, A. S. & Olsen, Christian Adam, May 2016, In: Nature Chemical Biology. 12, 5, p. 306-7 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Investigating the Sensitivity of NAD(+)-dependent Sirtuin Deacylation Activities to NADH

    Madsen, A. S., Andersen, C., Daoud, M., Anderson, K. A., Laursen, J. S., Chakladar, S., Huynh, F. K., Colaco, A. R., Backos, D. S., Fristrup, P., Hirschey, M. D. & Olsen, Christian Adam, 25 Mar 2016, In: Journal of Biological Chemistry. 291, 13, p. 7128-7141 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

    Galleano, I., Schiedel, M., Jung, M., Madsen, A. S. & Olsen, Christian Adam, 11 Feb 2016, In: Journal of Medicinal Chemistry. 59, 3, p. 1021-31 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A potent trifluoromethyl ketone histone deacetylase inhibitor exhibits class-dependent mechanism of action

    Madsen, A. S. & Olsen, Christian Adam, 2016, In: MedChemComm. 7, p. 464-470 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System

    Canovas de la Nuez, J., Baldry, M., Bojer, Martin Saxtorph, Andersen, P. S., Grzeskowiak, P. K., Stegger, M., Damborg, Peter Panduro, Olsen, Christian Adam & Ingmer, Hanne, 2016, In: Frontiers in Microbiology. 7, 1733.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions

    Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2015
  10. Published

    β-Peptoid Foldamers at Last

    Laursen, J. S., Engel-Andreasen, J. & Olsen, Christian Adam, 20 Oct 2015, In: Accounts of Chemical Research. 48, 10, p. 2696-704 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effects of Thionation and Fluorination on Cis-Trans Isomerization in Tertiary Amides: An Investigation of N-Alkylglycine (Peptoid) Rotamers

    Engel-Andreasen, J., Wich, K., Laursen, J. S., Harris, P. & Olsen, Christian Adam, 4 Mar 2015, In: Journal of Organic Chemistry. 80, 11, p. 5415–5427 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Triangular prism-shaped β-peptoid helices as unique biomimetic scaffolds

    Laursen, J. S., Harris, Pernille, Fristrup, P. & Olsen, Christian Adam, 2015, In: Nature Communications. 6, p. 1-10 10 p., 7013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2014
  14. Published

    An azumamide C analogue without the zinc-binding functionality

    Villadsen, J. S., Kitir, B., Wich, K., Friis, T., Madsen, A. S. & Olsen, Christian Adam, 12 Aug 2014, In: MedChemComm. 5, p. 1849-1855

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5

    Tan, M., Peng, C., Anderson, K. A., Xie, Z., Chhoy, P., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., Ro, J., Wagner, G. R., Green, M. F., Madsen, A. S., Schmiesing, J., Peterson, B. S., Xu, G., Ilkayeva, O. R., Muehlbauer, M. J., Braulke, T. & 8 others, Mühlhausen, C., Backos, D. S., Olsen, Christian Adam, McGuire, P. J., Pletcher, S. D., Lombard, D. B., Hirschey, M. D. & Zhao, Y., 1 Apr 2014, In: Cell Metabolism. 19, 4, p. 605–617

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    An Update on Lysine Deacylases Targeting the Expanding "Acylome"

    Olsen, Christian Adam, Mar 2014, In: ChemMedChem. 9, 3, p. 434-437 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11

    Madsen, A. S., Kristensen, H. M. E., Lanz, A. G. & Olsen, Christian Adam, Mar 2014, In: ChemMedChem. 9, 3, p. 614-626 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes

    Andreev, K., Bianchi, C., Laursen, J. S., Citterio, L., Hein-Kristensen, L., Gram, L., Kuzmenko, I., Olsen, Christian Adam & Gidalevitz, D., 2014, In: B B A - Biomembranes. 1838, 10, p. 2492-502 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles

    Maolanon, A. R., Villadsen, J. S., Christensen, Niels Johan, Hoeck, C., Friis, T., Harris, P., Gotfredsen, C. H., Fristrup, P. & Olsen, Christian Adam, 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9644-9657 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2013
  21. Published

    Total Synthesis and Full Histone Deacetylase Inhibitory Profiling of Azumamides A-E as Well as beta(2)- epi-Azumamide E and beta(3)-epi-Azumamide E

    Villadsen, J., Stephansen, H. M., Maolanon, A. R., Harris, Pernille & Olsen, Christian Adam, 22 Aug 2013, In: Journal of Medicinal Chemistry. 56, 16, p. 6512-6520

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Cis-Trans Amide Bond Rotamers in beta-Peptoids and Peptoids: Evaluation of Stereoelectronic Effects in Backbone and Side Chains

    Laursen, J. S., Engel-Andreasen, J., Fristrup, P., Harris, Pernille & Olsen, Christian Adam, 20 Feb 2013, In: Journal of the American Chemical Society. 135, 7, p. 2835-2844

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2012
  24. Published

    Macrocyclic Peptoid-Peptide Hybrids as Inhibitors of Class I Histone Deacetylases

    Olsen, Christian Adam, Montero, A., Leman, L. J. & Ghadiri, M. R., Sep 2012, In: ACS Medicinal Chemistry Letters. 3, 9, p. 749-753

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Substrates for Efficient Fluorometric Screening Employing the NAD-Dependent Sirtuin 5 Lysine Deacylase (KDAC) Enzyme

    Madsen, A. S. & Olsen, Christian Adam, 14 Jun 2012, In: Journal of Medicinal Chemistry. 55, 11, p. 5582-5590

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Discovery of HDAC Inhibitors That Lack an Active Site Zn2+-Binding Functional Group

    Vickers, C. J., Olsen, Christian Adam, Leman, L. J. & Ghadiri, M. R., Jun 2012, In: ACS Medicinal Chemistry Letters. 3, 6, p. 505-508

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Expansion of the Lysine Acylation Landscape

    Olsen, Christian Adam, 2012, In: Angewandte Chemie International Edition. 51, 16, p. 3755-3756

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Profiling of Substrates for Zinc-dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

    Olsen, Christian Adam & Madsen, A., 2012, In: Angewandte Chemie International Edition. 51, 36, p. 9083-9087

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives

    Hansen, A. N., Bendiksen, C. D., Sylvest, L., Friis, T., Stærk, Dan, Jørgensen, Flemming Steen, Olsen, Christian Adam & Houen, G., 2012, In: P L o S One. 7, 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2011
  31. Published

    Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides That Restore Trafficking and Activity of Delta F508-CFTR

    Hutt, D. M., Olsen, Christian Adam, Vickers, C. J., Herman, D., Chalfant, M. A., Montero, A., Leman, L. J., Burkle, R., Maryanoff, B. E., Balch, W. E. & Ghadiri, M. R., Sep 2011, In: ACS Medicinal Chemistry Letters. 2, 9, p. 703-707

    Research output: Contribution to journal › Journal article › Research › peer-review

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