A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
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A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark. / O’Regan, Elisabeth; Svalgaard, Ingrid Bech; Sørensen, Anna Irene Vedel; Spiliopoulos, Lampros; Bager, Peter; Nielsen, Nete Munk; Hansen, Jørgen Vinsløv; Koch, Anders; Ethelberg, Steen; Hviid, Anders.
In: Nature Communications, Vol. 14, No. 1, 6266, 2023.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
AU - O’Regan, Elisabeth
AU - Svalgaard, Ingrid Bech
AU - Sørensen, Anna Irene Vedel
AU - Spiliopoulos, Lampros
AU - Bager, Peter
AU - Nielsen, Nete Munk
AU - Hansen, Jørgen Vinsløv
AU - Koch, Anders
AU - Ethelberg, Steen
AU - Hviid, Anders
N1 - Publisher Copyright: © 2023, Springer Nature Limited.
PY - 2023
Y1 - 2023
N2 - Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here, we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1–9 months after the RT-PCR test date. Being female, 50–65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions.
AB - Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here, we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1–9 months after the RT-PCR test date. Being female, 50–65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions.
U2 - 10.1038/s41467-023-42048-1
DO - 10.1038/s41467-023-42048-1
M3 - Journal article
C2 - 37805514
AN - SCOPUS:85173635560
VL - 14
JO - Nature Communications
JF - Nature Communications
SN - 2041-1723
IS - 1
M1 - 6266
ER -
ID: 370472624