Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG

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Altered cortical causality after remifentanil administration in healthy volunteers : A novel approach for pharmaco-EEG. / Khodayari-Rostamabad, Ahmad; Graversen, Carina; Olesen, Soren S; Malver, Lasse P; Kurita, Geana P; Sjogren, Per; Christrup, Lona Louring; Drewes, Asbjorn M.

In: I E E E Engineering in Medicine and Biology Society. Conference Proceedings, Vol. 2014, 08.2014, p. 4290-4293.

Research output: Contribution to journalConference articleResearchpeer-review

Harvard

Khodayari-Rostamabad, A, Graversen, C, Olesen, SS, Malver, LP, Kurita, GP, Sjogren, P, Christrup, LL & Drewes, AM 2014, 'Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG', I E E E Engineering in Medicine and Biology Society. Conference Proceedings, vol. 2014, pp. 4290-4293. https://doi.org/10.1109/EMBC.2014.6944573

APA

Khodayari-Rostamabad, A., Graversen, C., Olesen, S. S., Malver, L. P., Kurita, G. P., Sjogren, P., Christrup, L. L., & Drewes, A. M. (2014). Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG. I E E E Engineering in Medicine and Biology Society. Conference Proceedings, 2014, 4290-4293. https://doi.org/10.1109/EMBC.2014.6944573

Vancouver

Khodayari-Rostamabad A, Graversen C, Olesen SS, Malver LP, Kurita GP, Sjogren P et al. Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG. I E E E Engineering in Medicine and Biology Society. Conference Proceedings. 2014 Aug;2014:4290-4293. https://doi.org/10.1109/EMBC.2014.6944573

Author

Khodayari-Rostamabad, Ahmad ; Graversen, Carina ; Olesen, Soren S ; Malver, Lasse P ; Kurita, Geana P ; Sjogren, Per ; Christrup, Lona Louring ; Drewes, Asbjorn M. / Altered cortical causality after remifentanil administration in healthy volunteers : A novel approach for pharmaco-EEG. In: I E E E Engineering in Medicine and Biology Society. Conference Proceedings. 2014 ; Vol. 2014. pp. 4290-4293.

Bibtex

@inproceedings{e6ca714e62e04ae7bdb7794d4715a95a,
title = "Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG",
abstract = "Alterations in cortical causality information flow induced by remifentanil infusion in healthy volunteers was investigated in a placebo-controlled double-blind cross-over study. For each of the 21 enrolled male subjects, 2.5 minutes of resting electroencephalography (EEG) data were collected before and after infusion of remifentanil and placebo. Additionally, to assess cognitive function and analgesic effect, continuous reaction time (CRT) and bone pressure and heat pain were assessed, respectively. The causality information was extracted from the EEG by phase slope index (PSI). Among the features being reproducible between the two baseline recordings, several PSI features were altered by remifentanil administration in comparison to placebo. Furthermore, several of the PSI features altered by remifentanil were correlated to changes in both CRT and pain scores. The results indicate that remifentanil administration influence the information flow between several brain areas. Hence, the EEG causality approach offers the potential to assist in deciphering the cortical effects of remifentanil administration.",
author = "Ahmad Khodayari-Rostamabad and Carina Graversen and Olesen, {Soren S} and Malver, {Lasse P} and Kurita, {Geana P} and Per Sjogren and Christrup, {Lona Louring} and Drewes, {Asbjorn M}",
year = "2014",
month = aug,
doi = "10.1109/EMBC.2014.6944573",
language = "English",
volume = "2014",
pages = "4290--4293",
journal = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
issn = "0589-1019",
publisher = "IEEE Signal Processing Society",

}

RIS

TY - GEN

T1 - Altered cortical causality after remifentanil administration in healthy volunteers

T2 - A novel approach for pharmaco-EEG

AU - Khodayari-Rostamabad, Ahmad

AU - Graversen, Carina

AU - Olesen, Soren S

AU - Malver, Lasse P

AU - Kurita, Geana P

AU - Sjogren, Per

AU - Christrup, Lona Louring

AU - Drewes, Asbjorn M

PY - 2014/8

Y1 - 2014/8

N2 - Alterations in cortical causality information flow induced by remifentanil infusion in healthy volunteers was investigated in a placebo-controlled double-blind cross-over study. For each of the 21 enrolled male subjects, 2.5 minutes of resting electroencephalography (EEG) data were collected before and after infusion of remifentanil and placebo. Additionally, to assess cognitive function and analgesic effect, continuous reaction time (CRT) and bone pressure and heat pain were assessed, respectively. The causality information was extracted from the EEG by phase slope index (PSI). Among the features being reproducible between the two baseline recordings, several PSI features were altered by remifentanil administration in comparison to placebo. Furthermore, several of the PSI features altered by remifentanil were correlated to changes in both CRT and pain scores. The results indicate that remifentanil administration influence the information flow between several brain areas. Hence, the EEG causality approach offers the potential to assist in deciphering the cortical effects of remifentanil administration.

AB - Alterations in cortical causality information flow induced by remifentanil infusion in healthy volunteers was investigated in a placebo-controlled double-blind cross-over study. For each of the 21 enrolled male subjects, 2.5 minutes of resting electroencephalography (EEG) data were collected before and after infusion of remifentanil and placebo. Additionally, to assess cognitive function and analgesic effect, continuous reaction time (CRT) and bone pressure and heat pain were assessed, respectively. The causality information was extracted from the EEG by phase slope index (PSI). Among the features being reproducible between the two baseline recordings, several PSI features were altered by remifentanil administration in comparison to placebo. Furthermore, several of the PSI features altered by remifentanil were correlated to changes in both CRT and pain scores. The results indicate that remifentanil administration influence the information flow between several brain areas. Hence, the EEG causality approach offers the potential to assist in deciphering the cortical effects of remifentanil administration.

U2 - 10.1109/EMBC.2014.6944573

DO - 10.1109/EMBC.2014.6944573

M3 - Conference article

C2 - 25570941

VL - 2014

SP - 4290

EP - 4293

JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

SN - 0589-1019

ER -

ID: 129915625