Blood-brain distribution of morphine-6-glucuronide in sheep

Research output: Contribution to journalJournal articleResearchpeer-review

At present there are few data regarding the rate and extent of brain-blood partitioning of the opioid active metabolite of morphine, morphine-6-glucuronide (M6G). In this study the cerebral kinetics of M6G were determined, after a short-term intravenous infusion, in chronically instrumented conscious sheep.
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume149
Issue number6
Pages (from-to)754-60
Number of pages7
ISSN0007-1188
DOIs
Publication statusPublished - Nov 2006

    Research areas

  • Animals, Blood-Brain Barrier, Chromatography, High Pressure Liquid, Morphine Derivatives, Sheep

ID: 46098279