Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment
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Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment. / Andersen, Gertrud; Christrup, Lona Louring; Sjøgren, Per; Hansen, Steen Honoré; Jensen, Niels-Henrik.
In: Journal of Pain and Symptom Management, Vol. 23, No. 2, 02.2002, p. 161-4.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment
AU - Andersen, Gertrud
AU - Christrup, Lona Louring
AU - Sjøgren, Per
AU - Hansen, Steen Honoré
AU - Jensen, Niels-Henrik
PY - 2002/2
Y1 - 2002/2
N2 - A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.
AB - A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.
KW - Analgesics, Opioid
KW - Central Nervous System Stimulants
KW - Humans
KW - Male
KW - Middle Aged
KW - Morphine
KW - Morphine Derivatives
KW - Pain
KW - Prostatic Neoplasms
KW - Time Factors
M3 - Journal article
C2 - 11844638
VL - 23
SP - 161
EP - 164
JO - Journal of Pain and Symptom Management
JF - Journal of Pain and Symptom Management
SN - 0885-3924
IS - 2
ER -
ID: 46099105