Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre

Research output: Contribution to journal › Journal article › Research › peer-review

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Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. / Sjøgren, Per; Christrup, Lona Louring; Petersen, Morten Aa; Højsted, Jette.

In: European Journal of Pain, Vol. 9, No. 4, 08.2005, p. 453-62.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sjøgren, P, Christrup, LL, Petersen, MA & Højsted, J 2005, 'Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre', European Journal of Pain, vol. 9, no. 4, pp. 453-62. https://doi.org/10.1016/j.ejpain.2004.10.005

APA

Sjøgren, P., Christrup, L. L., Petersen, M. A., & Højsted, J. (2005). Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. European Journal of Pain, 9(4), 453-62. https://doi.org/10.1016/j.ejpain.2004.10.005

Vancouver

Sjøgren P, Christrup LL, Petersen MA, Højsted J. Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. European Journal of Pain. 2005 Aug;9(4):453-62. https://doi.org/10.1016/j.ejpain.2004.10.005

Author

Sjøgren, Per ; Christrup, Lona Louring ; Petersen, Morten Aa ; Højsted, Jette. / Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. In: European Journal of Pain. 2005 ; Vol. 9, No. 4. pp. 453-62.

Bibtex

@article{82896793a2124aba981d4a151eca6e47,
title = "Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre",
abstract = "The aim of the study was to investigate the influence of pain, sedation, pain medications and socio-demographics on cognitive functioning in chronic non-malignant pain patients. Chronic non-malignant pain patients (N=91) treated in a multidisciplinary pain centre were compared with age and sex matched healthy volunteers (N=64). Furthermore four subgroups of patients were examined: Group 1 (N=21) received no pain medications, group 2 (N=19) were in long-term oral opioid treatment, group 3 (N=18) were treated with antidepressants and/or anticonvulsants and group 4 (N=33) were treated with a combination of long-term oral opioids and antidepressants and/or anticonvulsants. Assessments comprised pain (PVAS) and sedation (SVAS), Continuous Reaction Time (CRT) testing for sustained attention, Finger Tapping Test (FTT) testing for psychomotor speed, Paced Auditory Serial Addition Task (PASAT) testing for information processing and working memory and Mini Mental State Examination (MMSE). CRT and FTT were impaired in the total patient sample. Treatment with opioids was associated with poorer performance of PASAT. High scores of PVAS and SVAS were associated with poor performance of PASAT and CRT, respectively. MMSE seems to be too insensitive for detecting the milder forms of cognitive impairment found in chronic non-malignant patients.",
keywords = "Adult, Aged, Analgesics, Analgesics, Opioid, Anticonvulsants, Antidepressive Agents, Chronic Disease, Cognition, Cognition Disorders, Denmark, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Pain Clinics, Pain Measurement, Pain, Intractable, Psychomotor Performance, Treatment Outcome",
author = "Per Sj{\o}gren and Christrup, {Lona Louring} and Petersen, {Morten Aa} and Jette H{\o}jsted",
year = "2005",
month = aug,
doi = "10.1016/j.ejpain.2004.10.005",
language = "English",
volume = "9",
pages = "453--62",
journal = "European Journal of Pain",
issn = "1090-3801",
publisher = "JohnWiley & Sons Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre

AU - Sjøgren, Per

AU - Christrup, Lona Louring

AU - Petersen, Morten Aa

AU - Højsted, Jette

PY - 2005/8

Y1 - 2005/8

N2 - The aim of the study was to investigate the influence of pain, sedation, pain medications and socio-demographics on cognitive functioning in chronic non-malignant pain patients. Chronic non-malignant pain patients (N=91) treated in a multidisciplinary pain centre were compared with age and sex matched healthy volunteers (N=64). Furthermore four subgroups of patients were examined: Group 1 (N=21) received no pain medications, group 2 (N=19) were in long-term oral opioid treatment, group 3 (N=18) were treated with antidepressants and/or anticonvulsants and group 4 (N=33) were treated with a combination of long-term oral opioids and antidepressants and/or anticonvulsants. Assessments comprised pain (PVAS) and sedation (SVAS), Continuous Reaction Time (CRT) testing for sustained attention, Finger Tapping Test (FTT) testing for psychomotor speed, Paced Auditory Serial Addition Task (PASAT) testing for information processing and working memory and Mini Mental State Examination (MMSE). CRT and FTT were impaired in the total patient sample. Treatment with opioids was associated with poorer performance of PASAT. High scores of PVAS and SVAS were associated with poor performance of PASAT and CRT, respectively. MMSE seems to be too insensitive for detecting the milder forms of cognitive impairment found in chronic non-malignant patients.

AB - The aim of the study was to investigate the influence of pain, sedation, pain medications and socio-demographics on cognitive functioning in chronic non-malignant pain patients. Chronic non-malignant pain patients (N=91) treated in a multidisciplinary pain centre were compared with age and sex matched healthy volunteers (N=64). Furthermore four subgroups of patients were examined: Group 1 (N=21) received no pain medications, group 2 (N=19) were in long-term oral opioid treatment, group 3 (N=18) were treated with antidepressants and/or anticonvulsants and group 4 (N=33) were treated with a combination of long-term oral opioids and antidepressants and/or anticonvulsants. Assessments comprised pain (PVAS) and sedation (SVAS), Continuous Reaction Time (CRT) testing for sustained attention, Finger Tapping Test (FTT) testing for psychomotor speed, Paced Auditory Serial Addition Task (PASAT) testing for information processing and working memory and Mini Mental State Examination (MMSE). CRT and FTT were impaired in the total patient sample. Treatment with opioids was associated with poorer performance of PASAT. High scores of PVAS and SVAS were associated with poor performance of PASAT and CRT, respectively. MMSE seems to be too insensitive for detecting the milder forms of cognitive impairment found in chronic non-malignant patients.

KW - Adult

KW - Aged

KW - Analgesics

KW - Analgesics, Opioid

KW - Anticonvulsants

KW - Antidepressive Agents

KW - Chronic Disease

KW - Cognition

KW - Cognition Disorders

KW - Denmark

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Neuropsychological Tests

KW - Pain Clinics

KW - Pain Measurement

KW - Pain, Intractable

KW - Psychomotor Performance

KW - Treatment Outcome

U2 - 10.1016/j.ejpain.2004.10.005

DO - 10.1016/j.ejpain.2004.10.005

M3 - Journal article

C2 - 15979026

VL - 9

SP - 453

EP - 462

JO - European Journal of Pain

JF - European Journal of Pain

SN - 1090-3801

IS - 4

ER -

ID: 46098352