NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
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- Danish NMR meeting 2015 SISO
Submitted manuscript, 15.6 MB, PDF document
Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to control
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
Original language | English |
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Publication date | 2015 |
Number of pages | 1 |
Publication status | Published - 2015 |
Event | 36th Danish NMR Meeting - Lund, Sweden Duration: 19 Jan 2015 → 20 Jan 2015 |
Conference
Conference | 36th Danish NMR Meeting |
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Country | Sweden |
City | Lund |
Period | 19/01/2015 → 20/01/2015 |
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ID: 130334039