Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets. / Christrup, Lona Louring; Angelo, H.R.; Bonde, J.; Kristensen, F.; Rasmussen, S.N.

In: Acta Pharmaceutica Nordica, Vol. 2, No. 2, 01.01.1990, p. 83-88.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Christrup, LL, Angelo, HR, Bonde, J, Kristensen, F & Rasmussen, SN 1990, 'Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets', Acta Pharmaceutica Nordica, vol. 2, no. 2, pp. 83-88.

APA

Christrup, L. L., Angelo, H. R., Bonde, J., Kristensen, F., & Rasmussen, S. N. (1990). Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets. Acta Pharmaceutica Nordica, 2(2), 83-88.

Vancouver

Christrup LL, Angelo HR, Bonde J, Kristensen F, Rasmussen SN. Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets. Acta Pharmaceutica Nordica. 1990 Jan 1;2(2):83-88.

Author

Christrup, Lona Louring ; Angelo, H.R. ; Bonde, J. ; Kristensen, F. ; Rasmussen, S.N. / Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets. In: Acta Pharmaceutica Nordica. 1990 ; Vol. 2, No. 2. pp. 83-88.

Bibtex

@article{023d905a668345b78d0900b99ef67905,
title = "Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets",
abstract = "Methadone administered in chewing gum in doses of 16.7-22.6 mg to seven patients in a study using an open balanced cross-over design, was compared with 20 mg of methadone given perorally as tablets. There was no significant difference in the AUC/D obtained after administration of chewing gum and tablets (p>0.05). It is concluded that the chewing gum formulation should be considered for further testing with respect to suppression of abstinence syndrome in narcotic addicts.",
author = "Christrup, {Lona Louring} and H.R. Angelo and J. Bonde and F. Kristensen and S.N. Rasmussen",
year = "1990",
month = jan,
day = "1",
language = "English",
volume = "2",
pages = "83--88",
journal = "Acta Pharmaceutica Nordica",
issn = "1100-1801",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets

AU - Christrup, Lona Louring

AU - Angelo, H.R.

AU - Bonde, J.

AU - Kristensen, F.

AU - Rasmussen, S.N.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - Methadone administered in chewing gum in doses of 16.7-22.6 mg to seven patients in a study using an open balanced cross-over design, was compared with 20 mg of methadone given perorally as tablets. There was no significant difference in the AUC/D obtained after administration of chewing gum and tablets (p>0.05). It is concluded that the chewing gum formulation should be considered for further testing with respect to suppression of abstinence syndrome in narcotic addicts.

AB - Methadone administered in chewing gum in doses of 16.7-22.6 mg to seven patients in a study using an open balanced cross-over design, was compared with 20 mg of methadone given perorally as tablets. There was no significant difference in the AUC/D obtained after administration of chewing gum and tablets (p>0.05). It is concluded that the chewing gum formulation should be considered for further testing with respect to suppression of abstinence syndrome in narcotic addicts.

UR - http://www.scopus.com/inward/record.url?scp=0025311038&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0025311038

VL - 2

SP - 83

EP - 88

JO - Acta Pharmaceutica Nordica

JF - Acta Pharmaceutica Nordica

SN - 1100-1801

IS - 2

ER -

ID: 46100403