Wie Rezeptormutationen Arzneimittelwirkungen beeinflussen können
Research output: Contribution to journal › Comment/debate › Research › peer-review
Standard
Wie Rezeptormutationen Arzneimittelwirkungen beeinflussen können. / Reiner-Link, David; Hauser, Alexander S.
In: BioSpektrum, Vol. 28, No. 2, 2022, p. 140-143.Research output: Contribution to journal › Comment/debate › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Wie Rezeptormutationen Arzneimittelwirkungen beeinflussen können
AU - Reiner-Link, David
AU - Hauser, Alexander S.
N1 - Publisher Copyright: © 2022, Die Springer-Verlag GmbH.
PY - 2022
Y1 - 2022
N2 - Adverse reactions are one of the leading causes of death, hence understanding the underlying mechanisms at an individual level is one of the most important and long-standing challenges in personalized medicine. However, little is known about how variability in receptor drug targets affects drug response. Elucidating how genetic variants influence ligand binding, signaling and, ultimately, therapeutic effects is vital and could serve as the next important step in the field of pharmacogenomics.
AB - Adverse reactions are one of the leading causes of death, hence understanding the underlying mechanisms at an individual level is one of the most important and long-standing challenges in personalized medicine. However, little is known about how variability in receptor drug targets affects drug response. Elucidating how genetic variants influence ligand binding, signaling and, ultimately, therapeutic effects is vital and could serve as the next important step in the field of pharmacogenomics.
U2 - 10.1007/s12268-022-1721-x
DO - 10.1007/s12268-022-1721-x
M3 - Kommentar/debat
AN - SCOPUS:85127335423
VL - 28
SP - 140
EP - 143
JO - BioSpektrum
JF - BioSpektrum
SN - 0947-0867
IS - 2
ER -
ID: 302852132