Paul Robert Hansen

Paul Robert Hansen

Associate Professor


  1. 2017
  2. Published

    Chemical Synthesis of Antimicrobial Peptides.

    Münzker, L., Oddo, A. & Hansen, Paul Robert, 2017, Chemical Synthesis of Antimicrobial Peptides: Münzker L, Oddo A, Hansen PR. Methods Mol Biol. 2017; . Hansen, P. R. (ed.). Springer, Vol. 1548. p. 35-49.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  3. Published

    Hemolytic Activity of Antimicrobial Peptides

    Oddo, A. & Hansen, Paul Robert, 2017, Methods in molecular biology. Hansen, P. R. (ed.). Springer, Vol. 1548. p. 427-435

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

    Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2016
  6. Published
  7. Published

    An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

    Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, Anders, Thulstrup, Peter Waaben, Sanderson, J. M. & Hansen, Paul Robert, 2016, In: ACS Medicinal Chemistry Letters. 7, 8, p. 741-745 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2015
  10. Published

    Solid-Phase Peptide Synthesis of Human alfa-Calcitonin Gene-Related Peptide and Two Fluorescent Analogs.

    Fuente-Moreno, M., Oddo, A., Sheykhzade, Majid, Pickering, Darryl S & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium . 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  11. Published

    Amphibian antimicrobial peptide fallaxin analogue FL9 affects virulence gene expression and DNA replication in Staphylococcus aureus

    Gottschalk, S., Gottlieb, C. T., Vestergaard, M., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 1 Dec 2015, In: Journal of Medical Microbiology. 64, 12, p. 1504-1513 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Novel classes of antimicrobials in veterinary medicine: Characterizing peptoids as topical agents for dog skin infections

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Vasir, J., Watts, J., Hummel, B. D. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  13. Published

    Novel compounds with selective antimicrobial activity against Staphylococcus pseudintermedius and Pseudomonas aeruginosa causing pyoderma in dogs

    Greco, I., Emborg, A., Oddo, A., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Short linear peptide-peptoid hybrids as potential antimicrobial drugs: Abstract for the 24th American Peptide Symposium

    Greco, I., Damborg, Peter Panduro, Jana, B. & Hansen, Paul Robert, 1 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    Fmoc Solid-Phase Peptide Synthesis

    Hansen, Paul Robert & Oddo, A., 2015, Methods in Molecular Biology: Peptide Antibodies. Vol. 1348. p. 33-50 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Peptide-Carrier Conjugation: Methods in Molecular Biology

    Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibodies. Vol. 1348. p. 51-57 7 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Antibodies with specificity for native and denatured forms of ovalbumin differ in reactivity between enzyme-linked immunosorbent assays.

    Holm, B. E., Bergmann, A. C., Hansen, Paul Robert, Koch, C., Houen, G. & Trier, N. H., 1 Feb 2015, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 123, 2, p. 136–145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structure-Activity Relationship Study of Lysine-Based Antimicrobial α-Peptide/β-Peptoid Oligomers

    Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 2015.

    Research output: Contribution to conferencePosterResearch

  19. Published

    An ANOVA-based model to identify the optimal antimicrobial peptide in a combination matrix

    Munk, J. K., Ritz, C., Fliedner, F. P., Frimodt-Moller, N. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  20. Published

    Antimicrobial activities of synthetic anoplin analogues against methicillin-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus faecium and Candida albicans

    Munk, J. K., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Moller, N., Nyberg, N., Wimmer, R. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    Peptide Macrocycles Featuring a Backbone Secondary Amine: A Convenient Strategy for the Synthesis of Lipidated Cyclic and Bicyclic Peptides on Solid Support

    Oddo, A., Münzker, L. & Hansen, Paul Robert, 2015, In: Organic Letters. 17, 10, p. 2502-2505 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide

    Oddo, A., Nyberg, N., Frimodt-Møller, N., Thulstrup, Peter Waaben & Hansen, Paul Robert, 2015, In: European Journal of Medicinal Chemistry. 102, p. 574-581 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Characterization of synthetic peptides by mass spectrometry

    Prabhala, B. K., Mirza, Osman Asghar, Højrup, P. & Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Efficient, regioselective ring-opening of activated aziridine-2-carboxylates with [18F]fluoride

    Schjøth-Eskesen, C., Hansen, Paul Robert, Kjær, Andreas & Gillings, N., 2015, In: ChemistryOpen. 4, 1, p. 65–71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    [64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

    Schjøth-Eskesen, C., Nielsen, Carsten Haagen, Heissel, S., Højrup, P., Hansen, Paul Robert, Gillings, N. & Kjær, A., 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

    Trier, N. H., Dam, C., Olsen, D., Hansen, Paul Robert & Houen, G., 2015, In: P L o S One. p. 1-12 12 p., 0144707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Rational Design of alpha-helical antimicrobial peptides: DOs and DON’Ts

    Uggerhøj, L. E., Poulsen, T. J., Munk, J. K., Fredborg, M., Sondergaard, T. E., Frimodt-Møller, N., Hansen, Paul Robert & Wimmer, R., 2015, In: ChemBioChem. 16, 2, p. 242–253 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Identifying immunogenic CD4+ T-cell epitopes of Myeloid cell leukemia 1 using overlapping 20-mer peptides spanning the whole protein.

    Woodworth, J. S., Agger, E. M. & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium Ved Srivastava, Andrei Yudin, and Michal Lebl (Editors) American Peptide Society. p. 262-63 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  29. 2014
  30. Published

    Identification and fine mapping of a linear B cell epitope of human vimentin

    Dam, C. E., Houen, G., Hansen, Paul Robert & Trier, N., 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 6, p. 506-514 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    Invited Lecture: From Host Defence Peptides to New Antibiotics

    Hansen, Paul Robert, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  33. Published
  34. Published

    Novel method to identify the optimal antimicrobial peptide in a combination matrix, using anoplin as an example

    Munk, J., Ritz, C., Fliedner, F. P., Frimodt-Møller, N. & Hansen, Paul Robert, 2014, In: Antimicrobial Agents and Chemotherapy. 58, 2, p. 1063-1070 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Ring flexibility as a key design feature for cyclic antimicrobial peptides

    Oddo, A., Frimodt-Møller, N. & Hansen, Paul Robert, 4 Jun 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2

    Tronstrøm, J., Dragborg, A. H., Hansen, Paul Robert, Houen, G. & Trier, N. H., 2014, In: Protein and Peptide Letters. 21, 1, p. 25-31 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Structural features of peptoid-peptide hybrids in lipid-water interfaces

    Uggerhøj, L. E., Munk, J. K., Hansen, Paul Robert, Güntert, P. & Wimmer, R., 2014, In: F E B S Letters. 588, 17, p. 3291–3297 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation

    Woodworth, J., Aagaard, C., Hansen, Paul Robert, Cassidy, J., Agger, E. M. & Andersen, P., 2014, In: The Journal of Immunology. 192, 7, p. 3247-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2013
  40. Published

    The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

    Gottschalk, S., Ifrah, D., Søndergaard, S. L., Gottlieb, C. T., Cohn, M. T., Hiasa, H., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 2013, In: B M C Microbiology. 13, 8 p., 192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A Novel Peptide-Peptoid Hybrid Active Against MRSP Skin Infections

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 4 Nov 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  42. Published
  43. Published

    Synthesis of antimicrobial peptoids

    Hansen, Paul Robert & Munk, J., 2013, Peptide synthesis and applications. 2nd ed. Vol. 1047. p. 151-159 (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  44. Published

    Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus

    Kjelstrup, S., Hansen, P. M. P., Thomsen, Line Elnif, Hansen, Paul Robert & Løbner-Olesen, Anders, 2013, In: P L o S One. 8, 9, 13 p., e72273.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A Minimal Labor Approach to Identifying the Optimal Anoplin Analog using ANOVA.

    Munk, J., Ritz, C., Petrine Fliedner, F., Frimodt-Møller, N. & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  46. Published

    Synthetic analogs of anoplin show improved antimicrobial activities

    Munk, J., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Møller, N., Wimmer, R., Nyberg, N. T. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 11, p. 669-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The Structure of the Central Side Chain is Crucial for Anoplin Hemolytic Activity

    Munk, J., Thøgersen, L., Uggerhøj, L. E., Wimmer, R., Frimodt-Møller, N., Lindorff-Larsen, Kresten & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium. Lebl, M. (ed.). American Peptide Society

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  48. Published

    De novo design of novel cyclic antimicrobial peptides

    Oddo, A., Frimodt-Moller, N. & Hansen, Paul Robert, 7 Jul 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  49. Published

    Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

    Welner, S., Trier, N. H., Morten Frisch, M., Locht, H., Hansen, Paul Robert & Houen, G., 2013, In: Molecular Cancer. 12, 1, 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

    Welner, S., Trier, N. H., Houen, G. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 2, p. 95-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2012
  52. Published

    Fine mapping of a monoclonal antibody to the N-Methyl D-aspartate receptor reveals a short linear epitope

    Amrutkar, S. D., Trier, N. H., Hansen, Paul Robert & Houen, G., 2012, In: Journal of Peptide Science. 98, 6, p. 567-575 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, Peter Panduro, Skindersø, M. E., Hansen, Paul Robert, Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, Luca, Aug 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  54. Published

    Antimikrobielle peptider: et nyt våben mod multiresistente bakterier

    Munk, J., Hansen, Paul Robert & Franzyk, Henrik, 2012, In: Lægemiddelforskning. 2012, p. 9-11

    Research output: Contribution to journalJournal articleCommunication

  55. Published

    Cross-reactivity of a human IgG1 anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

    Trier, N. H., Leth, M. L., Hansen, Paul Robert & Houen, G., 31 Dec 2012, In: Protein Science. 21, 12, p. 1929-1941

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Identification of continuous epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

    Trier, N. H., Hansen, Paul Robert, Vedeler, C. A., Somnier, F. E. & Houen, G., 2012, In: Journal of Neuroimmunology. 243, 1, p. 25-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4237511