Anders A. Jensen
Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
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Characteristics of stably expressed human dopamine D1a and D1b receptors: atypical behavior of the dopamine D1b receptor
Pedersen, U. B., Norby, B., Jensen, Anders A., Schiødt, M., Hansen, A., Suhr-Jessen, P., Scheideler, M., Thastrup, Ole & Andersen, P. H., 1994, In: European Journal of Pharmacology. 267, 1, p. 85-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors
Sandager-Nielsen, K., Ahring, P. K., Klein, J., van Hout, M., Thaneshwaran, S., Brito dos Santos, Altair, Jacobsen, T. A., Amrutkar, D. V., Peters, D., Jensen, Anders A., Kohlmeier, Kristi Anne, Christophersen, P. & Dyhring, T., 2020, In: Biochemical Pharmacology. 174, 13 p., 113786.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of AN6001, the first positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors
van Hout, M., Klein, J., Ahring, P. K., Brown, D. T., Thaneshwaran, S., Brito dos Santos, Altair, Jensen, Anders A., Kohlmeier, Kristi Anne, Christophersen, P. & Dyhring, T., 2020, In: Biochemical Pharmacology. 174, 113788.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling
Krzywkowski, K. M., Davies, P. A., Irving, A. J., Bräuner, Hans & Jensen, Anders A., 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 12, p. 1027-1040Research output: Contribution to journal › Journal article › Research › peer-review
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Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2
Sagot, E., Jensen, Anders A., Pickering, Darryl S, Pu, X., Umberti, M., Stensbøl, T. B., Nielsen, Birgitte, Assaf, Z., Aboab, B., Bolte, J., Gefflaut, T. & Bunch, Lennart, 2008, In: Journal of Medicinal Chemistry. 51, 14, p. 4085-4092 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters
Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, Anders A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 2013, In: Journal of Medicinal Chemistry. 56, 4, p. 1614-1628Research output: Contribution to journal › Journal article › Research › peer-review
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Chemoenzymatic synthesis and pharmacological characterization of functionalized aspartate analogues as novel excitatory amino acid transporter inhibitors
Fu, H., Zhang, J., Tepper, P. G., Bunch, Lennart, Jensen, Anders A. & Poelarends, G. J., 13 Sep 2018, In: Journal of Medicinal Chemistry. 61, 17, p. 7741-7753Research output: Contribution to journal › Journal article › Research › peer-review
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Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3
Alaux, S., Kusk, M., Sagot, E., Bolte, J., Jensen, Anders A., Bräuner, Hans, Gefflaut, T. & Bunch, Lennart, 2005, In: Journal of Medicinal Chemistry. 48, 25, p. 7980-92 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cloning and characterization of a functional human ¿-aminobutyric acid (GABA) transporter, human GAT-2
Christiansen, B., Meinild, A., Jensen, Anders A. & Bräuner, Hans, 2007, In: Journal of Biological Chemistry. 282, 27, p. 19331-19341 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D
Bräuner, Hans, Jensen, Anders A., Sheppard, P. O., Larsen, Birger Brodin, Krogsgaard-Larsen, Povl & O'Hara, P., 2001, In: BBA General Subjects. 1518, 3, p. 237-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of biophysical properties of α1β2 and α3β2 GABAA receptors in whole-cell patch-clamp electrophysiological recordings
Olander, E. R., Janzen , D., Villmann , C. & Jensen, Anders A., 2020, In: P L o S One. 15, 6, 13 p., e0234080.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational transitions of the serotonin 5-HT3 receptor
Polovinkin, L., Hassaine, G., Perot, J., Neumann, E., Jensen, Anders A., Lefebvre, S. N., Corringer, P., Neyton, J., Chipot, C., Dehez, F., Schoehn, G. & Nury, H., Nov 2018, In: Nature. 563, 7730, p. 275-279 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations
de la Fuente Revenga, M., Balle, T., Jensen, Anders A. & Frølund, Bente, 2015, In: European Journal of Medicinal Chemistry. 102, p. 352-362 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor
Jensen, Anders A., Sheppard, P. O., Jensen, L. B., O'Hara, P. J. & Bräuner, Hans, 2001, In: Journal of Biological Chemistry. 276, 13, p. 10110-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands
Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, Anders A., Lehel, S., Gillings, N., Herth, Matthias Manfred, Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Bioorganic & Medicinal Chemistry. 24, p. 5353-5356 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Copper and protons directly activate the zinc-activated channel
Trattnig, S. M., Gasiorek, A., Deeb, T. Z., Comenencia Ortiz, E. J., Moss, S. J., Jensen, Anders A. & Davies, P. A., 2016, In: Biochemical Pharmacology. 103, p. 109-117 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dark Classics in Chemical Neuroscience: NBOMes
Poulie, Christian Bernard Matthijs, Jensen, Anders A., Halberstadt, A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. p. 3860–3869 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors
Olander, E. R., Madjroh, Nawid, Bunch, Lennart, Söderhielm, P. C. & Jensen, Anders A., 2018, In: Biochemical Pharmacology. 150, p. 305-319Research output: Contribution to journal › Journal article › Research › peer-review
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Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors
Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes
Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters
Poulie, Christian Bernard Matthijs, Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, Walden, Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, Birgitte, Frydenvang, Karla Andrea, Jensen, Anders A., Hansen, K. B., Pickering, Darryl S & Bunch, Lennart, 19 Jun 2019, In: A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design, Synthesis, and Pharmacological Characterization of Heterobivalent Ligands for the Putative 5-HT2A/mGlu2 Receptor Complex
Poulie, Christian Bernard Matthijs, Liu, N., Jensen, Anders A. & Bunch, Lennart, 2020, In: Journal of Medicinal Chemistry. 63, 17, p. 9928-9949 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design, synthesis and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists
Crestey, F., Jensen, Anders A., Borch, M., Andreasen T., Jesper, Andersen, J., Balle, T. & Kristensen, Jesper Langgaard, 2013, In: Journal of Medicinal Chemistry. 56, 23, p. 9673-9682Research output: Contribution to journal › Journal article › Research › peer-review
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Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102
Huynh, Tri Hien Viet, Abrahamsen, B., Madsen, K. K., Gonzalez-Franquesa, A., Jensen, Anders A. & Bunch, Lennart, 2012, In: Bioorganic & Medicinal Chemistry. 20, 23, p. 6831-6839Research output: Contribution to journal › Journal article › Research › peer-review
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Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties
Jensen, Anders A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, Petrine, Stensbøl, T. B., Gloriam, David E., Krogsgaard-Larsen, Povl & Frølund, Bente, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1211-27 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1298436
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A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE
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The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells
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Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings
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