Anne-Marie Heegaard

Anne-Marie Heegaard

Professor


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  1. Published

    Vitamin D receptor and estrogen receptor gene polymorphisms in postmenopausal Danish women: no relation to bone markers or serum lipoproteins

    Bagger, Y. Z., Hassager, Christian, Heegaard, Anne-Marie & Christiansen, C., 2000, In: Climacteric. 3, 2, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Vitamin D levels and the risk of prostate cancer and prostate cancer mortality

    Stroomberg, Hein Vincent, Vojdeman, F. J., Madsen, C. M., Helgstrand, J. T., Schwarz, Peter, Heegaard, Anne-Marie, Olsen, A., Tjønneland, Anne, Struer Lind, B., Brasso, K., Jørgensen, Henrik Løvendahl & Røder, Andreas, 2021, In: Acta Oncologica. 60, 3, p. 316-322 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Vitamin D levels and cancer incidence in 217,244 individuals from primary health care in Denmark

    Vojdeman, F. J., Madsen, C. M., Frederiksen, K., Durup, D., Olsen, A., Hansen, L., Heegaard, Anne-Marie, Lind, B., Tjønneland, Anne, Jørgensen, Henrik Løvendahl & Schwarz, Peter, 2019, In: International Journal of Cancer. 145, 2, p. 338-346 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Transforming growth factor beta stimulation of biglycan gene expression is potentially mediated by sp1 binding factors

    Heegaard, Anne-Marie, Xie, Z., Young, M. F. & Nielsen, K. L., 2004, In: Journal of Cellular Biochemistry. 93, 3, p. 463-75 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Topical Neuropeptide Y for Ischemic Skin Wounds

    Stangerup, T., Gjerdrum, Lise Mette Rahbek, Bzorek, M., Andersen, L., Heegaard, Anne-Marie, Jørgensen, Lars Nannestad & Ågren, Magnus, 2024, In: International Journal of Molecular Sciences. 25, 6, 14 p., 3346.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

    Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, Anne-Marie & Bjerrum, Ole Jannik, Feb 2018, In: European Journal of Pain. 22, 2, p. 282-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The role of purinergic receptors in cancer-induced bone pain

    Falk, S., Uldall, M. & Heegaard, Anne-Marie, 2012, In: Journal of Osteoporosis. p. Article ID 758181 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    The nociceptin/orphanin FQ receptor system as a target to alleviate cancer-induced bone pain in rats: Model validation and pharmacological evaluation

    Sliepen, S. H. J., Korioth, J., Christoph, T., Tzschentke, T. M., Diaz-delCastillo, M., Heegaard, Anne-Marie & Rutten, K., 2021, In: British Journal of Pharmacology. 178, 9, p. 1995-2007 13 p., 14899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The hph-1 mouse mutant deficient in tetrahydrobiopterin show reduced acute and chronic inflammatory pain

    Bjerrum, Ole Jannik, Nasser, A. & Heegaard, Anne-Marie, 2011.

    Research output: Contribution to conference › Poster › Research › peer-review

  11. Published

    The effect of gender on early colonic anastomotic wound healing

    Kjaer, Marie, Kristjánsdóttir, H., Andersen, L., Heegaard, Anne-Marie, Ågren, Magnus & Jørgensen, Lars Nannestad, 2018, In: International Journal of Colorectal Disease. 33, 9, p. 1269-1276 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation

    Schaller, S., Henriksen, K. S., Sveigaard, C., Heegaard, Anne-Marie, Hélix, N., Stahlhut, M., Ovejero, M. C., Johansen, J. V., Solberg, H., Andersen, T. L., Hougaard, D., Berryman, M., Shiødt, C. B., Sørensen, T. B., Lichtenberg, J., Christophersen, P., Foged, N., Delaissé, J., Engsig, M. T. & Karsdal, M. A., 2004, In: Journal of Bone and Mineral Research. 19, 7, p. 1144-53 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain

    Appel, C. K., Gallego-Pedersen, S., Andersen, L., Kristensen, S. B., Ding, M., Falk, S., Sayilekshmy, M., Gabel-Jensen, C. & Heegaard, Anne-Marie, 6 Jul 2017, In: Scientific Reports. 7, 1, 14 p., 4792.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The GTP-cyclohydrolase deficient mouse shows reduced acute pain perception

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie & Møller, L. B., 2010.

    Research output: Contribution to conference › Poster › Communication

  15. Published

    Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

    Xu, T., Bianco, P., Fisher, L. W., Longenecker, G., Smith, E., Goldstein, S., Bonadio, J., Boskey, A., Heegaard, Anne-Marie, Sommer, B., Satomura, K., Dominguez, P., Zhao, C., Kulkarni, A. B., Robey, P. G. & Young, M. F., 1998, In: Nature Genetics. 20, 1, p. 78-82 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

    Zhang, X. Y., Barakat, Ahmed, Diaz-delCastillo, M., Vollert, J., Sena, E. S., Heegaard, Anne-Marie, Rice, A. S. C. & Soliman, N., 2022, In: Pain. 163, 11, p. 2076-2102

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice

    Winding, B., NicAmhlaoibh, R., Misander, H., Høegh-Andersen, P., Andersen, T. L., Holst-Hansen, C., Heegaard, Anne-Marie, Foged, N. T., Brünner, N. & Delaissé, J., 2002, In: Clinical Cancer Research. 8, 6, p. 1932-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Structure, expression, and regulation of the major noncollagenous matrix proteins of bone

    Young, M. F., Kerr, J. M., Ibaraki, K., Heegaard, Anne-Marie & Robey, P. G., 1992, In: Clinical Orthopaedics and Related Research. 281, p. 275-94 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Structure and molecular regulation of bone matrix proteins

    Robey, P. G., Fedarko, N. S., Hefferan, T. E., Bianco, P., Vetter, U. K., Grzesik, W., Friedenstein, A., van der Pluijm, G., Mintz, K. P., Young, M. F., Kerr, J. M., Ibaraki, K. & Heegaard, Anne-Marie, 1 Jan 1993, In: Journal of Bone and Mineral Research. 8, 2 S, p. S483-S487

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Spinal neuronal correlates of tapentadol analgesia in cancer pain: A back-translational approach

    Falk, S., Patel, R., Heegaard, Anne-Marie, Mercadante, S. & Dickenson, A. H., 2015, In: European Journal of Pain. 19, 2, p. 152-158 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Smerteforskning, chilli con carne og floureserende stoffer

    Nielsen, C. K., Sheykhzade, Majid, Heegaard, Anne-Marie & Bjerrum, Ole Jannik, 2007, In: Lægemiddelforskning. p. 26-27

    Research output: Contribution to journal › Journal article › Communication

  22. Published

    Small leucine-rich proteoglycans in the aging skeleton

    Young, M. F., Bi, Y., Ameye, L., Xu, T., Wadhwa, S., Heegaard, Anne-Marie, Kilts, T. & Chen, X. D., 2006, In: Journal of Musculoskeletal and Neuronal Interactions. 6, 4, p. 364-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Response surface analysis of synergistic interactions of morphine and gabapentin in a rat model of postoperative pain.

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 19 Oct 2015.

    Research output: Contribution to conference › Poster › Research

  24. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach

    Papathanasiou, T., Juul, R. V., Gabel-Jensen, C., Kreilgaard, M., Heegaard, Anne-Marie & Lund, Trine Meldgaard, 1 Nov 2017, In: AAPS Journal. 19, 6, p. 1804–1813 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Proteinases in bone resorption: obvious and less obvious roles

    Delaissé, J., Engsig, M. T., Everts, V., del Carmen Ovejero, M., Ferreras, M., Lund, L., Vu, T. H., Werb, Z., Winding, B., Lochter, A., Karsdal, M. A., Troen, T., Kirkegaard, T., Lenhard, T., Heegaard, Anne-Marie, Neff, L., Baron, R. & Foged, N., 2000, In: Clinica Chimica Acta. 291, 2, p. 223-34 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance

    Kilts, T., Ameye, L., Syed-Picard, F., Ono, M., Berendsen, A. D., Oldberg, A., Heegaard, Anne-Marie, Bi, Y. & Young, M. F., 2009, In: Scandinavian Journal of Medicine & Science in Sports Online. 19, 4, p. 536-46 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Pain without nociceptors? Nav1.7-independent pain mechanisms

    Minett, M. S., Falk, S., Santana-Varela, S., Bogdanov, Y. D., Nassar, M. A., Heegaard, Anne-Marie & Wood, J. N., 30 Jan 2014, In: Cell Reports. 6, 2, p. 245-246

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    P2X7 receptor-mediated analgesia in cancer-induced bone pain

    Falk, S., D. Schwab, S., Frøsig-Jørgensen, M., Clausen, Rasmus Prætorius, Dickenson, A. & Heegaard, Anne-Marie, 13 Feb 2015, In: Neuroscience. 291, p. 93–105 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    P2X7 receptor-deficient mice are susceptible to bone cancer pain

    Hansen, R. R., Nielsen, C. K., Nasser, A., Thomsen, S. I. M., Eghorn, L. F., Pham, Y., Schulenburg, C., Syberg, S., Ding, M., Stojilkovic, S. S., Jorgensen, N. R. & Heegaard, Anne-Marie, 2011, In: Pain. 152, 8, p. 1766-76 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application

    Høegh-Andersen, P., Tankó, L. B., Andersen, T. L., Lundberg, C. V., Mo, J. A., Heegaard, Anne-Marie, Delaissé, J. & Christgau, S., 2004, In: Arthritis Research & Therapy. 6, 2, p. R169-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Oral bioavailability and bone-sparing effects of estetrol in an osteoporosis model

    Coelingh Bennink, H. J. T., Heegaard, Anne-Marie, Visser, M., Holinka, C. F. & Christiansen, C., 2008, In: Climacteric. 11, 1, p. 2-14

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Når kræft gør ondt i knoglerne

    Hald, A., Hansen, R. R. & Heegaard, Anne-Marie, 2007, In: Lægemiddelforskning.

    Research output: Contribution to journal › Journal article › Communication

  34. Published

    Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

    Ågren, M. S., Andersen, T. L., Andersen, L., Schiødt, C. B., Surve, V., Andreassen, T. T., Risteli, J., Franzén, L. E., Delaissé, J., Heegaard, Anne-Marie & Jørgensen, Lars Nannestad, 2011, In: International Journal of Colorectal Disease. 26, 3, p. 329-337 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    No major effect of estrogen receptor gene polymorphisms on bone mineral density or bone loss in postmenopausal Danish women

    Bagger, Y. Z., Jørgensen, Henrik Løvendahl, Heegaard, Anne-Marie, Bayer, Lasse Razga, Hansen, L. & Hassager, Christian, 2000, In: Bone. 26, 2, p. 111-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

    Diaz del Castillo, M., Christiansen, S. H., Appel, C., Falk, S., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 29 May 2018, In: Neuroscience. 384, p. 111-119

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Neuropeptide Y and its involvement in chronic pain

    Diaz-delCastillo, M., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 1 Sep 2018, In: Neuroscience. 387, p. 162-169 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Neuropathic-like Pain in Fibrous Dysplasia/McCune-Albright Syndrome

    Spencer, T. L., Watts, L., Soni, A., Pinedo-Villanueva, R., Heegaard, Anne-Marie, Boyce, A. M. & Javaid, M. K., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 6, p. e2258-e2266

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Neuronal Sprouting and Reorganization in Bone Tissue Infiltrated by Human Breast Cancer Cells

    Hansen, R. B., Sayilekshmy, M., Sørensen, M. S., Jørgensen, A. H., Kanneworff, Ida Buur, Bengtsson, E. K. E., Grum-schwensen, T. A., Petersen, Michael Mørk, Ejersted, C., Andersen, Thomas Lund, Andreasen, C. M. & Heegaard, Anne-Marie, 2022, In: Frontiers in Pain Research. 3, p. 1-8 887747.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Myeloma-induced bone pain: lessons learnt from a localized, immunocompetent mouse model

    Diaz-delCastillo, M., Nemler, T., Thygesen, D. M., Chavez-Saldana, N. A., Vazquez-Mora, J. A., Palasca, Oana, Jensen, Lars Juhl, Evans, H., Andrews, R. E., Mandal, A., Chantry, A. D., Lawson, M. A., Andersen, T., Jimenez-Andrade, J. M. & Heegaard, Anne-Marie, 2022, In: Clinical Lymphoma, Myeloma & Leukemia. 22, Suppl., p. S108-S108 P-133.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Multiple myeloma—A painful disease of the bone marrow

    Diaz-delcastillo, M., Chantry, A. D., Lawson, M. A. & Heegaard, Anne-Marie, 2021, In: Seminars in Cell and Developmental Biology. 112, p. 49-58

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity

    Diaz-delCastillo, M., Hansen, R. B., Appel, C. K., Nielsen, Signe Lykke, Nielsen, S. N., Karyniotakis, K., Dahl, L. M., Andreasen, R. B. & Heegaard, Anne-Marie, 2020, In: Cancers. 12, 10, 19 p., 2740.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human

    Diaz-delCastillo, M., Palasca, O., Nemler, T. T., Thygesen, D. M., Chávez-Saldaña, N. A., Vázquez-Mora, J. A., Ponce Gomez, L. Y., Jensen, L. J., Evans, H., Andrews, R. E., Mandal, A., Neves, D., Mehlen, P., Caruso, J. P., Dougherty, P. M., Price, T. J., Chantry, A., Lawson, M. A., Andersen, T. L., Jimenez-Andrade, J. M. & 1 others, Heegaard, Anne-Marie, 2023, In: The Journal of Neuroscience. 43, 29, p. 5414-5430

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Measurement of tumor load and distribution in a model of cancer-induced osteolysis: a necessary precaution when testing novel anti-resorptive therapies

    Amhlaoibh, R. N., Hoegh-Andersen, P., Brünner, N., Sørensen, A., Winding, B., Holst-Hansen, C., Karsdal, M. A., Engsig, M. T., Delaissé, J. & Heegaard, Anne-Marie, 2004, In: Clinical and Experimental Metastasis. 21, 1, p. 65-74 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Lack of influence of collagen type Ialpha1 Sp1 binding site polymorphism on the rate of bone loss in a cohort of postmenopausal danish women followed for 18 years

    Heegaard, Anne-Marie, Jorgensen, H. L., Vestergaard, A. W., Hassager, C. & Ralston, S. H., 2000, In: Calcified Tissue International. 66, 6, p. 409-13 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism

    Sayilekshmy, M., Hansen, R. B., Delaissé, J. M., Rolighed, L., Andersen, T. L. & Heegaard, Anne-Marie, 1 Dec 2019, In: Scientific Reports. 9, 1, 14 p., 5361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Influence of sex differences on the progression of cancer-induced bone pain

    Falk, S., Uldall, M., Appel, C., Ding, M. & Heegaard, Anne-Marie, 2013, In: Anticancer Research. 33, 5, p. 1963-1969

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie, Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 Feb 2013, In: Molecular Pain. 9, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts

    Sato, T., del Carmen Ovejero, M., Hou, P. C. A., Heegaard, Anne-Marie, Kumegawa, M., Foged, N. & Delaissé, J., 1997, In: Journal of Cell Science. 110 ( Pt 5), p. 589-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat

    Durup, D., Diaz-delCastillo, M., Morgenlykke, J., Jensen, Lars Thorbjørn, Frandsen, E., Abelson, Klas, Pedersen, L., Lykkesfeldt, Jens, Ding, M., Jørgensen, Niklas Rye, Syberg, S., Petersen, S. & Heegaard, Anne-Marie, 2020, In: Endocrinology. 161, 8, bqaa100.

    Research output: Contribution to journal › Journal article › Research › peer-review

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