Small leucine-rich proteoglycans in the aging skeleton

Research output: Contribution to journalJournal articleResearchpeer-review

Small Leucine-Rich Proteoglyans (SLRPs) are major skeletal extracellular matrix (ECM) components that comprise a family of 13 members containing repeats of a leucine-rich motif. To examine SLRP function, we generated mice deficient in one or more member and analyzed them at the tissue, cell and molecular levels. This review outlines the novel research findings uncovered using these new animal models.
Original languageEnglish
JournalJournal of Musculoskeletal and Neuronal Interactions
Volume6
Issue number4
Pages (from-to)364-5
Number of pages2
ISSN1108-7161
Publication statusPublished - 2006

    Research areas

  • Aging, Amino Acid Motifs, Animals, Biglycan, Bone and Bones, Coculture Techniques, Decorin, Extracellular Matrix, Extracellular Matrix Proteins, Mice, Mice, Knockout, Models, Animal, Osteoblasts, Osteoclasts, Osteogenesis, Physical Conditioning, Animal, Proteoglycans

ID: 38426169