Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl

    de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  2. Published

    Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens

    Ziegler, H. L., Jensen, T. H., Christensen, J., Stærk, Dan, Hägerstrand, H., Sittie, A. A., Olsen, C. E., Staalsø, Trine, Ekpe, P. & Jaroszewski, J. W., 2002, In: Planta Medica. 68, p. 547-549 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed

    Ziegler, H. L., Hansen, Harald S., Stærk, Dan, Christensen, Søren Brøgger, Hägerstrand, H. & Jaroszewski, J. W., 2004, In: Antimicrobial Agents and Chemotherapy. 48, p. 4067-4071

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    New dammarane and malabaricane triterpenes from Caloncoba echinata

    Ziegler, H. L., Stærk, Dan, Christensen, J., Olsen, C. E., Sittie, A. A. & Jaroszewski, J. W., 2002, In: Journal of Natural Products. 65, p. 1764-1768

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues

    Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane

    Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme

    Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude root bark of Morus alba L.

    Zhao, Yong, Kongstad, Kenneth Thermann, Jäger, A. K., Nielsen, J. & Stærk, Dan, 2018, In: Journal of Chromatography A. 1556, p. 55-63

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Potential of Polygonum cuspidatum root as an antidiabetic food: Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic constituents

    Zhao, Yong, Chen, M. X., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, 2017, In: Journal of Agricultural and Food Chemistry. 65, p. 4421-4427

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity

    Zhao, Yong, Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg & Stærk, Dan, 2019, In: Phytochemistry. 166, p. 1-8 112054.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Unraveling the complexity of complex mixtures by combining high-resolution pharmacological, analytical and spectroscopic techniques: Antidiabetic constituents in Chinese medicinal plants

    Zhao, Yong, Kongstad, Kenneth Thermann, Liu, Y., He, C. & Stærk, Dan, 2019, In: Faraday Discussions. 218, p. 202-218

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts

    Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Orthogonal reversed-phase C18 and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata

    Zhao, Yong, Li, T., Kjaerulff, Louise, Venter, H., Coriani, S., Møller, Birger Lindberg, Semple, S. & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 12, p. 2638-2650

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Inhibition of α-glucosidase activity by selected edible seaweeds and fucoxanthin

    Zaharudin, N. B., Stærk, Dan & Dragsted, Lars Ove, 2019, In: Food Chemistry. 270, p. 481-486 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    High-resolution screening combined with HPLC–HRMS–SPE–NMR for identification of potential health-promoting constituents in sea aster and searocket - New nordic food ingredients

    Wubshet, S. G., Schmidt, J. S., Wiese, S. & Stærk, Dan, 2013, In: Journal of Agricultural and Food Chemistry. 61, 36, p. 8616-8623

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    High resolution antioxidant assay guided HPLC-HRMS-SPE-NMR analysis of Penicillium namyslowskii extract

    Wubshet, S. G., Nyberg, N. & Stærk, Dan, 2012.

    Research output: Contribution to conference › Poster › Research

  18. Published

    High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae)

    Wubshet, S. G., Moresco, H. H., Tahtah, Y., Brighente, I. M. C. & Stærk, Dan, 2015, In: Phytochemistry. 116, p. 246-252 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles.

    Wubshet, S. G., Liu, B., Kongstad, Kenneth Thermann, Böcker, U., Petersen, M. J., Li, T., Wang, J. & Stærk, Dan, 2019, In: Talanta. 200, p. 279-287

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Magnetic ligand fishing as a targeting tool for HPLC-HRMS-SPE-NMR: α-glucosidase inhibitory ligands and alkylresorcinol glycosides from Eugenia catharinae.

    Wubshet, S. G., Brighente, I. M. C., Moaddel, R. & Stærk, Dan, 2015, In: Journal of Natural Products. 78, 11, p. 2657-2665 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Identification of PTP1B and α-glucosidase inhibitory serrulatanes from Eremophila spp. by combined use of dual high-resolution PTP1B and α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR

    Wubshet, S. G., Tahtah, Y., Heskes, A. M., Kongstad, Kenneth Thermann, Pateraki, Irini, Hamberger, B. R., Møller, Birger Lindberg & Stærk, Dan, 2016, In: Journal of Natural Products. 79, 4, p. 1063-1072 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Targeting high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance analysis with high-resolution radical scavenging profiles - bioactive secondary metabolites from the endophytic fungus Penicillium namyslowskii

    Wubshet, S. G., Nyberg, N., Tejesvi, M. V., Pirttilä, A. M., Kajula, M., Mattila, S. & Stærk, Dan, 2013, In: Journal of Chromatography A. 1302, p. 34-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Identification of Fungal H+-ATPase Inhibitors by Microfractionation and HPLC-HRMS-SPE-NMR

    Wubshet, S. G., Kongstad, Kenneth Thermann, Johannesen, A., Nyberg, N., Jäger, A., Kjellerup, L., Vinther, A. & Stærk, Dan, 2014.

    Research output: Contribution to conference › Poster › Research

  24. Published

    Coupling HPLC-SPE-NMR with a microplate-based high-resolution antioxidant assay for efficient analysis of antioxidants in food – Validation and proof-of-concept study with caper buds

    Wiese, S., Wubshet, S. G., Nielsen, J. & Stærk, Dan, 2013, In: Food Chemistry. 141, 4, p. 4010-4018

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics

    Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.

    Research output: Contribution to conference › Poster › Research

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