Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    Jagten på bioaktive naturstoffer: Sammenkoblet HPLC-PDA-HRMS-SPE-NMR til hurtig identifikation af bioaktive naturstoffer i komplekse blandinger

    Stærk, Dan, 2021, In: Dansk Kemi. 102, 4, p. 40-44

    Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

  2. Published

    Labdanes and isopimaranes from Platycladus orientalis and their effects on erythrocyte membrane and on Plasmodium falciparum growth in the erythrocyte host cells

    Asili, J., Lambert, M., Ziegler, H. L., Stærk, Dan, Sairafianpour, M., Witt, M., Asghari, G., Ibrahimi, I. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, p. 631-637

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica

    Sairafianpour, M., Kayser, O., Christensen, J., Asfa, M., Witt, M., Stærk, Dan & Jaroszewski, J. W., 2003, In: Journal of Natural Products. 65, p. 1754-1768

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Leishmanicidal, antiplasmodial and cytotoxic activity of indole alkaloids from Corynanthe pachyceras

    Stærk, Dan, Lemmich, E., Christensen, J., Kharazmi, A., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Planta Medica. 66, p. 531-536

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones

    Sairafianpour, M., Christensen, J., Stærk, Dan, Budnik, B. A., Kharazmi, A., Bagherzadeh, K. & Jaroszewski, J. W., 2001, In: Journal of Natural Products. 64, 11, p. 1398-1403 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Ligand-fishing and bioactivity-correlated metabolomics for accelerated discovery of antidiabetic drug leads

    Nyberg, N. T., Wubshet, S. G., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  7. Published

    Lægemidler fra naturstoffer: fortid eller fremtid?

    Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

    Research output: Contribution to journal › Journal article › Communication

  8. Published

    Magnetic ligand fishing as a targeting tool for HPLC-HRMS-SPE-NMR: α-glucosidase inhibitory ligands and alkylresorcinol glycosides from Eugenia catharinae.

    Wubshet, S. G., Brighente, I. M. C., Moaddel, R. & Stærk, Dan, 2015, In: Journal of Natural Products. 78, 11, p. 2657-2665 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

    Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Microwave-assisted ring-opening of activated aziridines with resin-bound amines

    Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Moderne naturstofkemi: effektiv analyse af naturens stofbiblioteker

    Stærk, Dan, Lemmich, E., Franzyk, Henrik, Lemmich, J. & Jaroszewski, J. W., 2000, In: Lægemiddelforskning. p. 6-7

    Research output: Contribution to journal › Journal article › Communication

  12. Published

    Molecular phylogenetics as a predictive tool in plant-based drug discovery in the genus Euphorbia L.

    Ernst, M., Saslis Lagoudakis, H., Grace, O. M., Nilsson, N., Simonsen, H. T., Horn, J. W., Stærk, Dan & Rønsted, Nina, 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  13. Published

    Multivariate analysis of integrated and full-resolution 1H-NMR spectral data from complex pharmaceutical preparations: St. John's wort

    Rasmussen, B., Cloarec, O., Tang, H., Stærk, Dan & Jaroszewski, J. W., 2006, In: Planta Medica. 72, p. 556-563

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    NMR for gymnasieelever: forelæsningsslides, tabeller og opgavesamling til en NMR undervisningssession for gymnasieelever

    Stærk, Dan, 2010, Institut for Grundvidenskab og Miljø, Københavns Universitet. 39 p.

    Research output: Book/Report › Compendium/lecture notes › Education

  15. Published

    NMR-based metabolomics and hyphenated NMR techniques – a perfect match in natural products research

    Vinther, J. M., Wubshet, S. G. & Stærk, Dan, Aug 2015, Ethnopharmacology - a Reader. Heinrich, M. & Jäger, A. K. (eds.). Chichester: Wiley, p. 63-74

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)

    Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. & Stærk, Dan, 2015. 1 p.

    Research output: Contribution to conference › Poster › Research

  17. Published

    NMR-spectroscopic studies, and pharmacological evaluation of alkaloids from some medicinal plants

    Stærk, Dan, 2000, Royal Danish school of Pharmacy.

    Research output: Book/Report › Ph.D. thesis › Research

  18. Published

    Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila

    Gericke, Oliver, Fowler, R., Heskes, A., Bayly, M., Semple, S., Ndi, C. P., Stærk, Dan, Loland, Claus Juul, Murphy, D. J., Buirchell, B. & Møller, Birger Lindberg, 2021, In: Plant Journal. 108, 2, p. 555-578

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species

    Gericke, Oliver, Hansen, N. L., Pedersen, G. B., Kjaerulff, Louise, Luo, Dan, Stærk, Dan, Møller, Birger Lindberg, Pateraki, Irini & Heskes, A., 2020, In: B M C Plant Biology. 20, 15 p., 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    New bisbenzylisoquinoline alkaloid from Laureliopsis philippiana

    Stærk, Dan, Thi, L. P., Rasmussen, H. B., Guzmán, A. & Mølgaard, Per, 2009, In: Fitoterapia. 80, 2, p. 112-114 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    New dammarane and malabaricane triterpenes from Caloncoba echinata

    Ziegler, H. L., Stærk, Dan, Christensen, J., Olsen, C. E., Sittie, A. A. & Jaroszewski, J. W., 2002, In: Journal of Natural Products. 65, p. 1764-1768

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    New resistance-correlated saponins from the insect-resistant crucifer Barbarea vulgaris

    Nielsen, Nikoline Juul, Nielsen, J. & Stærk, Dan, 2010, In: Journal of Agricultural and Food Chemistry. 58, 9, p. 5509-5514 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR

    Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.

    Research output: Contribution to conference › Poster › Research

  24. Published

    Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR

    Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009. 1 p.

    Research output: Contribution to conference › Poster › Research

  25. Published

    Noter til M25-1 spektroskopi

    Stærk, Dan & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi. 49 p.

    Research output: Book/Report › Compendium/lecture notes › Education

  26. Published

    Når filmens fiktion bliver virkelighed

    Stærk, Dan, Lambert, M., Sairafianpour, M., Clarkson, C. & Jaroszewski, J. W., 2004, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journal › Journal article › Communication

  27. Published

    On the biosynthetic origin of carminic acid

    Rasmussen, S. A., Kongstad, Kenneth Thermann, Khorsand-Jamal, P., Kannangara, R. M., Nafisi, M., Van Dam, A., Bennedsen, M., Madsen, B., Okkels, F. T., Gotfredsen, C. H., Stærk, Dan, Thrane, U., Mortensen, U. H., Larsen, T. O. & Frandsen, R. J. N., 2018, In: Insect Biochemistry and Molecular Biology. 96, p. 51-61 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Orthogonal reversed-phase C18 and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata

    Zhao, Yong, Li, T., Kjaerulff, Louise, Venter, H., Coriani, S., Møller, Birger Lindberg, Semple, S. & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 12, p. 2638-2650

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme

    Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Oxidation and cyclization of Casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L

    Luo, Dan, Callari, R., Hamberger, B., Wubshet, S. G., Nielsen, M. T., Andersen-Ranberg, Johan, Hallström, B. M., Cozzi, F., Heider, H., Møller, Birger Lindberg, Stærk, Dan & Hamberger, B. R., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. E5082-E5089 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    PTP1B-inhibiting branched-chain fatty acid dimers from Eremophila oppositifolia subsp. angustifolia identified by high-resolution PTP1B inhibition profiling and HPLC-PDA-HRMS-SPE-NMR analysis

    Pedersen, H. A., Ndi, C., Semple, S. J., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 7 Apr 2020, In: Journal of Natural Products. 83, p. 1598-1610

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Peptides from chicken processing by-product inhibit DPP-IV and promote cellular glucose uptake: potential ingredients for T2D management

    Lima, R. D. C. L., Berg, R. S., Rønning, S. B., Afseth, N. K., Knutsen, S. H., Stærk, Dan & Wubshet, S. G., 2019, In: Food & Function. 10, p. 1619-1628

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Phenanthroindolizidine alkaloids from Vincetoxicum pumilum

    Stærk, Dan, Nezhad, K. B., Asili, J., Emami, S. A., Ahi, A., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Biochemical Systematics and Ecology. 33, p. 957-960

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Phytochemical investigation of Eremophila spp.

    Bredahl, E. K., Ergin, Y., Kjaerulff, Louise & Stærk, Dan, 2021, p. 1.

    Research output: Contribution to conference › Poster › Research

  35. Published

    Picraviane A and B: Nortriterpenes with limonoid-like skeletons containing a heptanolide E-ring system from Picramnia glazioviana

    Gimenes, L., Batista Junior, J. M., dos Santos Junior, F. M., Souza, M. D. S., Luna-Dulcey, L., Ellena, J., Cominetti, M. R., da Silva, M. F. D. G. F., Vieira, P. C., Fernandes, J. B. & Stærk, Dan, 2019, In: Phytochemistry. 163, p. 38-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora:

    Kesting, J. R., Tolderlund, I., Pedersen, A. F., Witt, M., Jaroszewski, J. W. & Stærk, Dan, 2009, In: Journal of Natural Products. 72, 2, p. 312-315 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Plantemetabolomer in action

    Schmidt, B., Stærk, Dan, Bro, Rasmus & Jaroszewski, J. W., 2006, In: Lægemiddelforskning. 2006, p. 4-5 2 p.

    Research output: Contribution to journal › Journal article › Research

  38. Published

    Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts

    Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens

    Ziegler, H. L., Jensen, T. H., Christensen, J., Stærk, Dan, Hägerstrand, H., Sittie, A. A., Olsen, C. E., Staalsø, Trine, Ekpe, P. & Jaroszewski, J. W., 2002, In: Planta Medica. 68, p. 547-549 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives

    Liang, Chao, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Journal of Functional Foods. 64, 10 p., 103623.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Potential of Polygonum cuspidatum root as an antidiabetic food: Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic constituents

    Zhao, Yong, Chen, M. X., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, 2017, In: Journal of Agricultural and Food Chemistry. 65, p. 4421-4427

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Potential of Sorbus berry extracts for management of type 2 diabetes: metabolomics investigation of 1H NMR spectra, α-amylase and α-glucosidase inhibitory activities, and in vivo anti-hyperglycaemic activity of S. norvegica

    Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2019, In: Journal of Ethnopharmacology. 242, 10 p., 112061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum

    Sørensen, J. L., Hansen, F. T., Søndergaard, T. E., Stærk, Dan, Lee, T. V., Wimmer, R., Klitgaard, L. G., Purup, S., Giese, H. & Frandsen, R. J. N., 2012, In: Environmental Microbiology. 14, 5, p. 1159-1170 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In: Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics

    Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.

    Research output: Contribution to conference › Poster › Research

  46. Published

    Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude root bark of Morus alba L.

    Zhao, Yong, Kongstad, Kenneth Thermann, Jäger, A. K., Nielsen, J. & Stærk, Dan, 2018, In: Journal of Chromatography A. 1556, p. 55-63

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica

    Lambert, M., Stærk, Dan, Hansen, S. H., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Journal of Natural Products. 68, p. 1500-1509

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Recreational drug use at a major music festival: trend analysis of anonymised pooled urine

    Hoegberg, L., Christiansen, C., Søe, J. L., Telving, R., Andreasen, M. F., Stærk, Dan, Christrup, Lona Louring & Kongstad, Kenneth Thermann, 2018, In: Clinical Toxicology. 56, p. 245-255 1360496.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock

    Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 2016, In: Journal of Ethnopharmacology. 186, p. 189-195 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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