David E. Gloriam

David E. Gloriam

Professor

ORCID: 0000-0002-4299-7561

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  1. Published

    24 Messages on a Sustainable Career in Research at UCPH

    Larsen, K. R. (ed.), Wegener, H. C., Stein, A., Bach, A., Williams, A. R., Gall, C., Gravert, C., Gloriam, D. E., Lorenzen, E., Yvanez, E., Cappellini, E., Poulsen, F., Mortensen, J., Bentzen, J. S., Shik, J. Z., Miskowiak, K. W., Elgaard, K. K. E., Jønsson, K. A., Won, K. J., Nørgaard, L. C. & 9 others, Cantarero Arevalo, Lourdes, Kristiansen, Maria, Lund, Marianne N., Borregaard, Michael Krabbe, Høyland-Kroghsbo, Nina Molin, Iversen, Rune, Viskum, U., Nosch, Marie Louise Bech & Hjorth, Jens, 2020, University of Copenhagen. 31 p.

    Research output: Book/Report › Report › Communication

  2. Published

    3-Substituted 2-phenyl-indoles: Privileged structures for medicinal chemistry

    Johansson, K. H., Jørgensen, T. B., Gloriam, David E., Bräuner, Hans & Pedersen, D. S., 21 Jan 2013, In: R S C Advances. 3, 3, p. 945-960

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

    Peng, Y., McCorvy, J. D., Harpsøe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajsen, L. F., Huang, X., Wu, Y., Shen, L., Bjørn-Yoshimoto, W. E., Ding, K., Wacker, D., Han, G. W., Cheng, J., Katritch, V., Jensen, A. A. & 6 others, Hanson, M. A., Zhao, S., Gloriam, David E., Roth, B. L., Stevens, R. C. & Liu, Z., 2018, In: Cell. 172, 4, p. 719-730 P719-730.E14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A Structural Framework for GPCR Chemogenomics: What’s In a Residue Number?

    Vass, M., Kooistra, Albert J., Verhoeven, S., Gloriam, David E., de Esch, I. J. P. & de Graaf, C., 1 Jan 2018, Methods in Molecular Biology. Humana Press, p. 73-113 41 p. (Methods in Molecular Biology, Vol. 1705).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  5. Published

    A community Biased Signaling Atlas

    Caroli, J., Mamyrbekov, A., Harpsøe, Kasper, Gardizi, S., Dörries, L., Ghosh, E., Hauser, Alexander Sebastian, Kooistra, Albert J. & Gloriam, David E., 2023, In: Nature Chemical Biology. 19, p. 531–535

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  6. Published

    A community standard format for the representation of protein affinity reagents

    Gloriam, D. E. I., Orchard, S., Bertinetti, D., Björling, E., Bongcam-Rudloff, E., Borrebaeck, C. A. K., Bourbeillon, J., Bradbury, A. R. M., de Daruvar, A., Dübel, S., Frank, R., Gibson, T. J., Gold, L., Haslam, N., Herberg, F. W., Hiltke, T., Hoheisel, J. D., Kerrien, S., Koegl, M., Konthur, Z. & 16 others, Korn, B., Landegren, U., Montecchi-Palazzi, L., Palcy, S., Rodriguez, H., Schweinsberg, S., Sievert, V., Stoevesandt, O., Taussig, M. J., Ueffing, M., Uhlén, M., van der Maarel, S., Wingren, C., Woollard, P., Sherman, D. J. & Hermjakob, H., 2010, In: Molecular and Cellular Proteomics. 9, 1, p. 1-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery

    Garland, S. L. & Gloriam, David E., 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors

    Fidom, K., Isberg, V., Hauser, Alexander Sebastian, Mordalski, S., Lehto, T., Bojarski, A. J. & Gloriam, David E., Jan 2015, In: Methods. 71, p. 104-112 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

    Nakamoto, C., Goto, Y., Tomizawa, Y., Fukata, Y., Fukata, M., Harpsøe, Kasper, Gloriam, David E., Aoki, K. & Takeuchi, T., 2021, In: Molecular Brain. 14, 1, 14 p., 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges

    Kufareva, I., Katritch, V., Biggin, P., Kim, M., Park, K., Jung, S. W., Cho, A. E., Sands, Z. A., Ostopovici-Halip, L., Bologa, C. G., Norn, C., Brylinski, M., Skolnick, J., Keränen, H., Lenselink, B. E., Van Westen, G., Overington, J. P., De Teráán, H. G., Isberg, V., Fidom, K. M. & 96 others, Lehto, T. M., Gloriam, David E., Ghosh, A., Sonavane, U., Joshi, R., Xia, J., Hsieh, J. H., Zhang, L., Wang, X. S., Vogel, H., Yuan, S., Feng, X., Chen, M., Ambia, J., Barth, P., Gageat, C., Stepniewski, M., Xhaard, H., Kelm, S., Pitt, W. R., Shi, J., Larsen, A., Li, H., Wagner, J., Bhattacharya, S., Vaidehi, N., Kanou, K., Cvicek, V., Kim, S. K., Trzaskowski, B., Goddard, W. A., Abrol, R., Selvam, B., Tikhonova, I. G., Cuzzolin, A., Sabbadin, D., Ciancetta, A., Moro, S., Freyd, T., Gabrielsen, M., Kristiansen, K., Sylte, I., Gaffney, K. J., Petasis, N. A., Latek, D., Bajda, M., Młynarczyk, K., Filipek, S., López, L., Kuiper, M., Beuming, T., Perez-Aguilar, J. M., Wang, R. Y. R., Park, H., Greisen, P., Song, Y., DiMaio, F., Baker, D., Shin, W. H., Heo, L., Lee, G. R., Seok, C., Yang, J., Zhang, Y., Ponassi, M., Rosano, C., Cheremovskiy, G., Grudinin, S., Chaudhari, R., Heim, A. J., Li, Z., Lv, Q., Grigorov, M. G., Hu, X., Sun, H., Shen, M., Southall, N., Jadhav, A., Rodríguez, D., Ranganathan, A., Carlsson, J., Najmanovich, R., Durdagi, S., De March, C., Diharce, J., Golebiowski, J., Antonczak, S., Fiorucci, S., Nguyen, E., Meiler, J., Gutcaits, A., Marti-Solano, M., Pastor, M., Selent, J., Stevens, R. C. & Abagyan, R., 2014, In: Structure. 22, 8, p. 1120-1139 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    An online GPCR structure analysis platform

    Kooistra, Albert J., Munk, C., Hauser, Alexander Sebastian & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 875-878

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    An online resource for GPCR structure determination and analysis

    Munk, C., Mutt, E., Isberg, V., Nikolajsen, L. F., Bibbe, J. M., Flock, T., Hanson, M. A., Stevens, R. C., Deupi, X. & Gloriam, David E., 2019, In: Nature Methods. 16, 2, p. 151-162

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils

    Christensen, H. B., Gloriam, David E., Pedersen, D. S., Cowland, J. B., Borregaard, N. & Bräuner, Hans, 15 Jul 2017, In: Journal of Pharmacological and Toxicological Methods. 88, Pt 1, p. 72-78 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Bigger is better in virtual drug screens

    Gloriam, David E., Feb 2019, In: Nature. 566, p. 193-194 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene

    Molck, C., Harpsøe, Kasper, Gloriam, David E., Kaae, B. H., Jimenez, H. N., Uberti, M. A., Topiol, S., Clausen, Rasmus Prætorius, Madsen, Ulf, Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, Sep 2011, In: Current Neuropharmacology. 9, p. 43-43

    Research output: Contribution to journal › Conference abstract in journal › Research

  16. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner, Hans, 23 Nov 2011, In: Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Chemogenomics of allosteric binding sites in GPCRs

    Gloriam, David E., 2013, In: Drug Discovery Today: Technologies. 10, 2, p. e307-13

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Combinatorial expression of GPCR isoforms affects signalling and drug responses

    Marti-Solano, M., Crilly, S. E., Malinverni, D., Munk, C., Harris, M., Pearce, A., Quon, T., Mackenzie, A. E., Wang, X., Peng, J., Tobin, A. B., Ladds, G., Milligan, G., Gloriam, David E., Puthenveedu, M. A. & Babu, M. M., 2020, In: Nature. 587, p. 650-656 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Common coupling map advances GPCR-G protein selectivity

    Hauser, Alexander Sebastian, Avet, C., Normand, C., Mancini, A., Inoue, A., Bouvier, M. & Gloriam, David E., 2022, In: eLife. 11, 22 p., e74107.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Community guidelines for GPCR ligand bias: IUPHAR review 32

    Kolb, P., Kenakin, T., Alexander, S. P. H., Bermudez, M., Bohn, L. M., Breinholt, C. S., Bouvier, M., Hill, S. J., Kostenis, E., Martemyanov, K. A., Neubig, R. R., Onaran, H. O., Rajagopal, S., Roth, B. L., Selent, J., Shukla, A. K., Sommer, M. E. & Gloriam, David E., 2022, In: British Journal of Pharmacology. 179, 14, p. 3651-3674

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

    Bartling, Christian Reinhard Otto, Alexopoulou, Flora, Kuschert, S., Chin, Y. K. Y., Jia, X., Sereikaité, Vita, Özcelik, D., Jensen, T. M., Jain, P., Nygaard, M. M., Harpsøe, Kasper, Gloriam, David E., Mobli, M. & Strømgaard, Kristian, 2023, In: Journal of Medicinal Chemistry. 66, 4, p. 3045-3057

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Comprehensive comparisons of the current human, mouse, and rat RefSeq, Ensembl, EST, and FANTOM3 datasets: identification of new human genes with specific tissue expression profile

    Nordström, K. J. V., Mirza, M. A. I., Larsson, T. P., Gloriam, David E., Fredriksson, R. & Schiöth, H. B., 29 Sep 2006, In: Biochemical and Biophysical Research Communications. 348, 3, p. 1063-74 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

    Bjarnadóttir, T. K., Gloriam, David E., Hellstrand, S. H., Kristiansson, H., Fredriksson, R. & Schiöth, H. B., Sep 2006, In: Genomics. 88, 3, p. 263-73 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Computer-aided discovery of aromatic L-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139

    Ísberg, V., Andersen, K. B., Bisig, C., Dietz, G. P., Bräuner, Hans & Gloriam, David E., 14 May 2014, In: Journal of Chemical Information and Modeling. 54, 6, p. 1553-1557 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

    Babbitt, P. C., Bagos, P. G., Bairoch, A., Bateman, A., Chatonnet, A., Chen, M. J., Craik, D. J., Finn, R. D., Gloriam, D., Haft, D. H., Henrissat, B., Holliday, G. L., Isberg, V., Kaas, Q., Landsman, D., Lenfant, N., Manning, G., Nagano, N., Srinivasan, N., O’Donovan, C. & 9 others, Pruitt, K. D., Sowdhamini, R., Rawlings, N. D., Saier, M. H., Sharman, J. L., Spedding, M., Tsirigos, Konstantinos, Vastermark, A. & Vriend, G., 18 May 2015, In: Database: The Journal of Biological Databases and Curation. 2015, p. 1-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Critical evaluation of the FANTOM3 non-coding RNA transcripts

    Nordström, K. J. V., Mirza, M. A. I., Almén, M. S., Gloriam, David E., Fredriksson, R. & Schiöth, H. B., 2009, In: Genomics. 94, 3, p. 169-176

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design

    Gloriam, David E., Foord, S. M., Blaney, F. E. & Garland, S. L., 2009, In: Journal of Medicinal Chemistry. 52, 14, p. 4429-4442

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

    Boesgaard, M. W., Harpsøe, Kasper, Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, Jesper M., König, G. M., Kostenis, E., Gloriam, David E. & Bräuner, Hans, 2020, In: Journal of Biological Chemistry. 295, 40, p. 13850-13861

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties

    Jensen, Anders A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, Petrine, Stensbøl, T. B., Gloriam, David E., Krogsgaard-Larsen, Povl & Frølund, Bente, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1211-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

    Di Giglio, M. G., Muttenthaler, M., Harpsøe, Kasper, Liutkeviciute, Z., Keov, P., Eder, T., Rattei, T., Arrowsmith, S., Wray, S., Marek, A., Elbert, T., Alewood, P. F., Gloriam, David E. & Gruber, C. W., 1 Feb 2017, In: Scientific Reports. 7, 15 p., 41002.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

    Zhang, X., Belousoff, M. J., Zhao, P., Kooistra, A. J., Truong, T. T., Ang, S. Y., Underwood, C. R., Egebjerg, T., Šenel, P., Stewart, G. D., Liang, Y-L., Glukhova, A., Venugopal, H., Christopoulos, A., Furness, S. G. B., Miller, L. J., Reedtz-Runge, S., Langmead, C. J., Gloriam, D. E., Danev, R. & 2 others, Sexton, P. M. & Wootten, D., 2020, In: Molecular Cell. 80, 3, p. 485-500

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites

    Krall, J., Bavo, Francesco, Falk-Petersen, C. B., Jensen, C. H., Nielsen, J. O., Tian, Yongsong, Anglani, V., Kongstad, Kenneth Thermann, Petersen, Louise Piilgaard, Nielsen, Birgitte, Gloriam, David E., Kehler, J., Jensen, Anders A., Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 14 Mar 2019, In: Journal of Medicinal Chemistry. 62, 5, p. 2798-2813

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Foster, S. R., Hauser, Alexander Sebastian, Vedel, L., Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner, Hans & Gloriam, David E., 31 Oct 2019, In: Cell. 179, 4, p. 895-908

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors

    Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In: Scientific Reports. 10, 1, 12 p., 10078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists

    Poulie, Christian Bernard Matthijs, Pottie, E., Simon, Icaro A, Harpsøe, Kasper, D'Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Stove, C. P. & Kristensen, Jesper Langgaard, 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

    Sandhu, M., Cho, A., Ma, N., Mukhaleva, E., Namkung, Y., Lee, S., Ghosh, S., Lee, J. H., Gloriam, David E., Laporte, S. A., Babu, M. M. & Vaidehi, N., 2022, In: Nature Communications. 13, 1, 14 p., 7428.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Editorial overview: New technologies: GPCR drug design and function-exploiting the current (of) structures

    Tautermann, C. S. & Gloriam, David E., 2 Aug 2016, In: Current Opinion in Pharmacology. 30, p. 7-10 4 p.

    Research output: Contribution to journal › Comment/debate › Research

  38. Published

    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

    Avet, C., Mancini, A., Breton, B., Le Gouill, C., Hauser, Alexander Sebastian, Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., St-Onge, S., Carrier, M., Héroux, M., Morissette, S., Fauman, E. B., Fortin, J. P., Schann, S., Leroy, X., Gloriam, David E. & Bouvier, M., 2022, In: eLife. 11, 34 p., e74101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at gamma-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters

    Giraudo, A., Krall, J., Bavo, Francesco, Nielsen, Birgitte, Kongstad, Kenneth Thermann, Rolando, B., De Blasio, R., Gloriam, David E., Löffler, R., Thiesen, L., Harpsøe, Kasper, Frydenvang, Karla Andrea, Boschi, D., Wellendorph, Petrine, Lolli, M. L., Jensen, Anders A. & Frølund, Bente, 27 Jun 2019, In: Journal of Medicinal Chemistry. 62, 12, p. 5797-5809

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations

    Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In: Journal of Chemical Information and Modeling. 51, 2, p. 315-325

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    G protein-coupled receptor pharmacology-The next generation

    Bräuner, Hans, Rosenkilde, Mette, Gether, Ulrik & Gloriam, David E., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Supplement 6, p. 3-4 2 p.

    Research output: Contribution to journal › Editorial › Research

  42. Published

    GPCR activation mechanisms across classes and macro/microscales

    Hauser, Alexander Sebastian, Kooistra, Albert J., Munk, C., Heydenreich, F. M., Veprintsev, D. B., Bouvier, M., Babu, M. M. & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 879-888

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    GPCRDB: an information system for G protein-coupled receptors

    Ísberg, V., Vroling, B., van der Kant, R., Li, K., Vriend, G. & Gloriam, David E., Jan 2014, In: Nucleic Acids Research. 42, Database issue, p. D422-D425

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    GPCRdb: an information system for G protein-coupled receptors

    Isberg, V., Mordalski, S., Munk, C., Rataj, K., Harpsøe, Kasper, Hauser, Alexander Sebastian, Vroling, B., Bojarski, A. J., Vriend, G. & Gloriam, David E., 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D356-64

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    GPCRdb in 2018: adding GPCR structure models and ligands

    Pándy-Szekeres, Gáspár, Munk, C., Tsonkov, T. M., Mordalski, S., Harpsøe, Kasper, Hauser, Alexander Sebastian, Bojarski, A. J. & Gloriam, David E., 2018, In: Nucleic Acids Research. 46, D1, 7 p., gkx1109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    GPCRdb in 2021: integrating GPCR sequence, structure and function

    Kooistra, Albert J., Mordalski, S., Pándy-Szekeres, Gáspár, Esguerra, M., Mamyrbekov, A., Munk, C., Keserű, G. M. & Gloriam, David E., 2021, In: Nucleic Acids Research. 49, D1, p. D335-D343

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

    Pándy-Szekeres, Gáspár, Caroli, J., Mamyrbekov, A., Kermani, A. A., Keserű, G. M., Kooistra, Albert J. & Gloriam, David E., 2023, In: Nucleic Acids Research. 51, D1, p. D395–D402

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    GPCRdb: The G protein-coupled receptor database - an introduction

    Munk, C., Isberg, V., Mordalski, S., Harpsøe, Kasper, Rataj, K., Hauser, Alexander Sebastian, Kolb, P., Bojarski, A. J., Vriend, G. & Gloriam, David E., Jul 2016, In: British Journal of Pharmacology. 173, 14, p. 2195-207 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    GPCRmd uncovers the dynamics of the 3D-GPCRome

    Rodríguez-Espigares, I., Torrens-Fontanals, M., Tiemann, J. K. S., Aranda-García, D., Ramírez-Anguita, J. M., Stepniewski, T. M., Worp, N., Varela-Rial, A., Morales-Pastor, A., Medel-Lacruz, B., Pándy-Szekeres, G., Mayol, E., Giorgino, T., Carlsson, J., Deupi, X., Filipek, S., Filizola, M., Gómez-Tamayo, J. C., Gonzalez, A., Gutiérrez-de-Terán, H. & 27 others, Jiménez-Rosés, M., Jespers, W., Kapla, J., Khelashvili, G., Kolb, P., Latek, D., Marti-Solano, M., Matricon, P., Matsoukas, M., Miszta, P., Olivella, M., Perez-Benito, L., Provasi, D., Ríos, S., Torrecillas, I. R., Sallander, J., Sztyler, A., Vasile, S., Weinstein, H., Zachariae, U., Hildebrand, P. W., De Fabritiis, G., Sanz, F., Gloriam, David E., Cordomi, A., Guixà-González, R. & Selent, J., 2020, In: Nature Methods. 17, 8, p. 777-787

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

    Huang, S., Xu, P., Shen, D., Simon, Icaro A, Mao, C., Tan, Y., Zhang, H., Harpsøe, Kasper, Li, H., Zhang, Y., You, C., Yu, X., Jiang, Y., Zhang, Y., Gloriam, David E. & Xu, H. E., 2022, In: Molecular Cell. 82, 14, p. 2681-2695.e6 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 5953796