Elisabeth Rexen Ulven

Elisabeth Rexen Ulven

Associate Professor


  1. 2013
  2. Reevaluation of Fatty acid receptor 1 (FFAR1/GPR40) as drug target for the stimulation of insulin secretion in humans

    Wagner, R., Kaiser, G., Gerst, F., Ulven, Elisabeth Rexen, Due-Hansen, M. E., Grundmann, M., Machicao, F., Peter, A., Kostenis, E., Ulven, Trond, Fritsche, A., Häring, H. & Ullrich, S., 1 Feb 2013, In: Diabetes. 62, 6, p. 2106-2111 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Mucus can change the permeation rank order of drug candidates

    Hagesaether, E., Ulven, Elisabeth Rexen, Due-Hansen, M. E. & Ulven, Trond, 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 276-282 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

    Hudson, B. D., Shimpukade, B., Mackenzie, A. E., Butcher, A. J., Pediani, J. D., Ulven, Elisabeth Rexen, Heathcote, H., Tobin, A. B., Ulven, Trond & Milligan, G., 2013, In: Molecular Pharmacology. 84, 5, p. 710-725 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2012
  6. Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

    Hudson, B. D., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Kostenis, E., Adams, D. R., Ulven, Trond & Milligan, G., 2012, In: F A S E B Journal. 26, 12, p. 4951-4965 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

    Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schröder, R., Hudson, B. D., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 14, p. 6624-6628 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2011
  9. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

    Schmidt, J., Smith, N. J., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Hudson, B. D., Ward, R. J., Drewke, C., Milligan, G., Kostenis, E. & Ulven, Trond, 10 Jan 2011, In: Journal of Biological Chemistry. 286, 12, p. 10628-10640 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40

    Schmidt, J., Liebscher, K., Merten, N., Grundmann, M., Mielenz, M., Sauerwein, H., Ulven, Elisabeth Rexen, Due-Hansen, M. E., Ulven, Trond, Ullrich, S., Gomeza, J., Drewke, C. & Kostenis, E., 2011, In: Journal of Biological Chemistry. 286, 14, p. 11890-11894 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties

    Ulven, Elisabeth Rexen, Urban, C., Grundmann, M., Due-Hansen, M. E., Hagesaether, E., Schmidt, J., Pardo, L., Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2011, In: Journal of Medicinal Chemistry. 54, 19, p. 6691-6703 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2010
  13. A Rapid and Efficient Sonogashira Protocol and Improved Synthesis of Free Fatty Acid 1 (FFA1) Receptor Agonists

    Ulven, Elisabeth Rexen, Due-Hansen, M. E. & Ulven, Trond, 19 Feb 2010, In: Journal of Organic Chemistry. 75, 4, p. 1301-1304 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

    Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, Karsten, Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2010, In: ACS Medicinal Chemistry Letters. 1, 7, p. 345-349 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

ID: 201719978