Matthias Manfred Herth

Matthias Manfred Herth

Professor


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  1. Published

    Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies

    IMBI Brain Imaging Working Group, I. B. I. W. G., 1 Dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 327-332 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

    IMBI Project, I. P., 1 Jan 2019, In: Alzheimer's and Dementia. 15, 8, p. 1081-1103

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, Anders A., Gillings, N., Lehel, S., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, Apr 2017, In: Organic & Biomolecular Chemistry. 15, p. 4351-4358

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Electrophilic fluorine-18 labeling of highly reactive tetrazine for the bioorthogonal click reaction

    Petersen, I., Kjær, Andreas, Herth, Matthias Manfred, Edem, P., Madsen, J., Bender, D., Kodahl, G. & Crestey, F., 1 May 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  5. Published

    One step synthesis of N-succidimidyl-4-[F-18]-fluorobenzoate ([F-18]SFB): [Meeting Abstract]

    Petersen, I., Kjær, Andreas, Herth, Matthias Manfred & Madsen, J., 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S201-S201 P-046 .

    Research output: Contribution to journal › Conference abstract in journal › Research

  6. Published

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, Anders A., Lehel, S., Gillings, N., Herth, Matthias Manfred, Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Bioorganic & Medicinal Chemistry. 24, p. 5353-5356 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    One-step synthesis of N-succinimidyl-4-[18F]Fluorobenzoate ([18F]SFB)

    Petersen, I. N., Madsen, J., Poulie, Christian Bernard Matthijs, Kjær, Andreas & Herth, Matthias Manfred, 22 Sep 2019, In: Molecules. 24, 19, 7 p., 3436.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Nucleophilic 18F-Labeling of Spirocyclic Iodonium Ylide or Boronic Pinacol Ester Precursors - Advantages and Disadvantages

    Petersen, I. N., Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 18 Jan 2017, In: European Journal of Organic Chemistry. 2017, 3, p. 453-458 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Evaluation of [Cu-64]Cu-NOTA-PEG7-H-Tz for Pretargeted Imaging in LS174T Xenografts-Comparison to [111In-111]In-DOTA-PEG11-BisPy-Tz

    Poulie, Christian Bernard Matthijs, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Kougioumtzoglou, G., Jeppesen, T. E., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Molecules. 26, 3, 9 p., 544.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Editorial: Prof. Frank Rösch's legacy in the radiopharmaceutical chemistry field

    Poulie, Christian Bernard Matthijs, Piel, M., Neumaier, B., Ross, T. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 3, 1336481.

    Research output: Contribution to journal › Editorial › Research › peer-review

  12. Published

    Next generation fibroblast activation protein (FAP) targeting PET tracers : The tetrazine ligation allows an easy and convenient way to 18F-labeled (4-quinolinoyl)glycyl-2-cyanopyrrolidines

    Poulie, Christian Bernard Matthijs, Shalgunov, Vladimir, Elvas, F., Van Rymenant, Y., Moon, E. S., Battisti, Umberto Maria, De Loose, J., De Meester, I., Rösch, F., Van Der Veken, P. & Herth, Matthias Manfred, 2023, In: European Journal of Medicinal Chemistry. 262, 10 p., 115862.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Bioorthogonal Click of Colloidal Gold Nanoparticles to Antibodies In vivo

    Poulie, Christian Bernard Matthijs, Sporer, E., Hvass, Lars, Jørgensen, Jesper Tranekjær, Kempen, Paul Joseph, Lopes van den Broek, S. I., Shalgunov, Vladimir, Kjær, Andreas, Jensen, A. I. & Herth, Matthias Manfred, 2022, In: Chemistry - A European Journal. 28, 61, 10 p., e202201847.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Development of the First Tritiated Tetrazine: Facilitating Tritiation of Proteins

    Radjani Bidesi, N. S., Battisti, Umberto Maria, Lopes van de Broek, S., Shalgunov, Vladimir, Dall, A., Bøggild Kristensen, J., Sehlin, D., Syvänen, S., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2022, In: ChemBioChem. 23, 23, 7 p., e202200539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Evaluation of the α-synuclein PET radiotracer (d3)-[11C]MODAG-001 in pigs

    Raval, N. R., Madsen, C. A., Shalgunov, Vladimir, Nasser, A., Battisti, Umberto Maria, Beaman, Emily Eufaula, Juhl, M., Jørgensen, Louise Møller, Herth, Matthias Manfred, Hansen, H. D., Plavén-Sigray, P. & Knudsen, Gitte Moos, 2022, In: Nuclear Medicine and Biology. 114-115, p. 42-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease

    Raval, N. R., Gudmundsen, F., Juhl, M., Andersen, Ida Vang, Speth, N., Videbæk, A., Petersen, I. N., Mikkelsen, Jens D., Fisher, P. M. D., Herth, Matthias Manfred, Plavén-Sigray, P., Knudsen, Gitte Moos & Palner, M., 2021, In: Frontiers in Synaptic Neuroscience. 13, 13 p., 715811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET

    Schlein, E., Rokka, J., Odell, L. R., van den Broek, S. L., Herth, Matthias Manfred, Battisti, Umberto Maria, Syvänen, S., Sehlin, D. & Eriksson, J., 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 12 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    P-Glycoprotein Influence on the Brain Uptake of a 5-HT2A Ligand: [F-18]MH.MZ

    Schmitt, U., Leed, D. E., Herth, Matthias Manfred, Piel, M., Buchholz, H., Roesch, F., Hiemke, C., Lueddens, H. & Debus, F., 2011, In: Neuropsychobiology. 63, 3, p. 183-190

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Preliminary Evaluation of (S)-7-[F-18]Fluorotryptophan as a Tracer for the Imaging of Serotonin Synthesis in Pig Brain

    Shalgunov, Vladimir, Raval, N. R., Donovan, L. L., Nasser, A., Zlatopolskiy, B. D., Neumaier, B., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, SUPPL 1, p. S639-S639 EP-267 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Blocking of efflux transporters in rats improves translational validation of brain radioligands

    Shalgunov, Vladimir, Xiong, M., L’Estrade, E. T., Raval, N. R., Andersen, Ida Vang, Edgar, F. G., Speth, N. R., Baerentzen, S. L., Hansen, H. D., Donovan, L. L., Nasser, A., Peitersen, S. T., Kjær, Andreas, Knudsen, Gitte Moos, Syvänen, S., Palner, M. & Herth, Matthias Manfred, 2020, In: EJNMMI Research. 10, 1, 11 p., 124.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Evaluation of F-537-Tetrazine in a model for brain pretargeting imaging. Comparison to N-(3-[18F] fluoro-5-(1,2,4,5-tetrazin-3-yl)benzyl)propan-1-amine

    Shalgunov, Vladimir, van den Broek, S. L., Andersen, Ida Vang, Raval, N. R., Schäfer, G., Barz, M., Herth, Matthias Manfred & Battisti, Umberto Maria, 2024, In: Nuclear Medicine and Biology. 128-129, 12 p., 108877.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Convenient access to F-18-labeled amines through the Staudinger reduction

    Shalgunov, Vladimir, Steen, J., Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S205-S206 P-050.

    Research output: Contribution to journal › Conference abstract in journal › Research

  23. Published

    SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain

    Shalgunov, Vladimir, Lilius, T., Sigurosson, B., Baerentzen, S. L., Hauglund, Natalie Linea, Herth, Matthias Manfred, Palner, M. & Nedergaard, Maiken, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supplement 1, p. S404-S405 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    Radiolabeling of a polypeptide polymer for intratumoral delivery of alpha-particle emitter, 225Ac, and beta-particle emitter, 177Lu

    Shalgunov, Vladimir, Engudar, G., Bohrmann, L., Wharton, L., Maskell, K., Johann, K., Barz, M., Schaffer, P., Herth, Matthias Manfred & Radchenko, V., 2022, In: Nuclear Medicine and Biology. 104-105, p. 11-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A SPECT-based method for dynamic imaging of the glymphatic system in rats

    Sigurdsson, B., Hauglund, Natalie Linea, Lilius, T. O., Mogensen, F. L. H., Mortensen, K. N., Beschorner, Natalie, Klinger, L., Bærentzen, S. L., Rosenholm, Marko, Shalgunov, Vladimir, Herth, Matthias Manfred, Mori, Yuki & Nedergaard, Maiken, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 7, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Surface Adsorption of the Alpha-Emitter Astatine-211 to Gold Nanoparticles Is Stable In Vivo and Potentially Useful in Radionuclide Therapy

    Sporer, E., Poulie, Christian Bernard Matthijs, Lindegren, S., Aneheim, E., Jensen, H., Bäck, T., Kempen, Paul Joseph, Kjær, Andreas, Herth, Matthias Manfred & Jensen, A. I., 2021, In: Journal of Nanotheranostics. 2, 4, p. 196-207

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Covalent core-radiolabeling of polymeric micelles with125I/211At for theranostic radiotherapy

    Sporer, E., Poulie, Christian Bernard Matthijs, Bäck, T., Lindegren, S., Jensen, H., Kempen, Paul Joseph, Kjær, Andreas, Herth, Matthias Manfred & Jensen, A. I., 2022, In: Nanotheranostics. 6, 4, p. 388-399

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Clearing and Masking Agents in Pretargeting Strategies

    Staudt, Markus & Herth, Matthias Manfred, 2023, In: Pharmaceuticals. 16, 4, 15 p., 497.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Development of 11C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species

    Staudt, Markus, Shalgunov, Vladimir, Nedergaard, Maiken & Herth, Matthias Manfred, 2023, In: Journal of Labelled Compounds and Radiopharmaceuticals. 66, 12, p. 393-399

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry

    Steen, E. J. L., Jørgensen, Jesper Tranekjær, Denk, C., Battisti, Umberto Maria, Norregaard, K., Edem, P. E., Bratteby, K., Shalgunov, Vladimir, Wilkovitsch, M., Svatunek, D., Poulie, Christian Bernard Matthijs, Hvass, Lars, Simon, M., Wanek, T., Rossin, R., Robillard, M., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: ACS Pharmacology & Translational Science. 4, 2, p. 824-833 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging: [Meeting Abstract]

    Steen, J., Norregard, K., Johann, K., Jørgensen, Jesper Tranekjær, Svatunek, D., Birke, A., Edem, P., Rossin, R., Seidl, C., Schmid, F., Robillard, M., Mikula, H., Kristensen, Jesper Langgaard, Barz, M., Kjær, Andreas & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S109-S110

    Research output: Contribution to journal › Conference abstract in journal › Research

  32. Published

    Towards the Dual Click F-18-labeling of Antibodies

    Steen, J., Denk, C., Norregaard, K., Jorgensen, J., Rossin, R., Svatunek, D., Edem, P., Robillard, M., Kjær, Andreas, Kristensen, Jesper Langgaard, Mikula, H. & Herth, Matthias Manfred, 1 May 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  33. Published

    Pretargeted PET imaging using a dual click F-18-labeling strategy: [Meeting Abstract]

    Steen, J., Denk, C., Jørgensen, Jesper Tranekjær, Norregard, K., Rossin, R., Wilkovitsch, M., Svatunek, D., Edem, P., Kuntner, C., Wanek, T., Robillard, M., Kristensen, Jesper Langgaard, Kjær, Andreas, Mikula, H. & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S22-S23 O-08.

    Research output: Contribution to journal › Conference abstract in journal › Research

  34. Published

    Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices

    Stéen, E. J. L., Nyberg, N., Lehel, S., Andersen, V. L., Di Pilato, P., Knudsen, Gitte Moos, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 15 Jan 2017, In: Bioorganic & Medicinal Chemistry Letters. 27, 2, p. 319-322 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Pretargeting in nuclear imaging and radionuclide therapy: Improving efficacy of theranostics and nanomedicines

    Stéen, E. J. L., Edem, P. E., Nørregaard, K., Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Kjær, Andreas & Herth, Matthias Manfred, Oct 2018, In: Biomaterials. 179, p. 209-245 37 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Johann, K., Norregaard, K., Sohr, B., Svatunek, D., Birke, A., Shalgunov, Vladimir, Edem, P. E., Rossin, R., Seidl, C., Schmid, F., Robillard, M. S., Kristensen, Jesper Langgaard, Mikula, H., Barz, M., Kjær, Andreas & Herth, Matthias Manfred, 2020, In: ACS Nano. 14, 1, p. 568-584

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction

    Stéen, E. J. L., Shalgunov, Vladimir, Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2019, In: European Journal of Organic Chemistry. 2019, 8, p. 1722-1725

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Cover Feature: Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction (Eur. J. Org. Chem. 8/2019)

    Stéen, E. J. L., Shalgunov, Vladimir, Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 28 Feb 2019, In: European Journal of Organic Chemistry. 2019, 8, p. 1686-1686

    Research output: Contribution to journal › Journal article › Communication

  39. Published

    Improved radiosynthesis and preliminary in vivo evaluation of the 11 C-labeled tetrazine [ 11 C]AE-1 for pretargeted PET imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Petersen, I. N., Nørregaard, K., Lehel, S., Shalgunov, Vladimir, Birke, A., Edem, P. E., L'Estrade, E. T., Hansen, H. D., Villadsen, J., Erlandsson, M., Ohlsson, T., Yazdani, A., Valliant, J. F., Kristensen, Jesper Langgaard, Barz, M., Knudsen, Gitte Moos, Kjær, Andreas & Herth, Matthias Manfred, 1 Jan 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 8, p. 986-990

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Classics in Neuroimaging: The Serotonergic 2A Receptor System-from Discovery to Modern Molecular Imaging

    T L'Estrade, E., Hansen, H. D., Erlandsson, M., Ohlsson, T. G., Knudsen, Gitte Moos & Herth, Matthias Manfred, 20 Jun 2018, In: ACS Chemical Neuroscience. 9, 6, p. 1226-1229 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Development and Evaluation of Two Potential 5-HT7 Receptor PET Tracers: [18F]ENL09 and [18F]ENL10

    Tampio L'Estrade, E., Xiong, M., Shalgunov, Vladimir, Edgar, F. G., Volk, B., Baerentzen, S. L., Palner, M., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2019, In: ACS Chemical Neuroscience. 10, 9, p. 3961-3968 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [18F]ENL30: A Potential PET Radiotracer for the 5-HT7 Receptor

    Tampio L'Estrade, E., Edgar, F. G., Xiong, M., Shalgunov, Vladimir, Baerentzen, S. L., Erlandsson, M., Ohlsson, T. G., Palner, M., Knudsen, Gitte Moos & Herth, Matthias Manfred, 23 Apr 2019, In: ACS Omega. 4, 4, p. 7344-7353

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Fragment-based labeling using condensation reactions of six potential 5-HT7R PET tracers

    Tampio L'Estrade, E., Shalgunov, Vladimir, Lehel, S., Nymann Petersen, I., Poulie, Christian Bernard Matthijs, Edgar, F. G., Volk, B., Ohlsson, T., Erlandsson, M., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: Journal of Radioanalytical and Nuclear Chemistry. 326, p. 1749-1762 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    11C-imaging: methyl jasmonate moves in both phloem and xylem, promotes transport of jasmonate, and of photoassimilate even after proton transport is decoupled

    Thorpe, M. R., Ferrieri, A. P., Herth, Matthias Manfred & Ferrieri, R. A., Jul 2007, In: Planta. 226, 2, p. 541-51 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Direct Aromatic F-18-labeling of Tetrazines: A Rapid and Convenient Entry to Tetrazines for Pretargeted PET Imaging [Meeting Abstract]

    Vazquez, R. G., Battisti, Umberto Maria, Stares, D. L., Petersen, I. N., Crestey, F., Svatunek, D., Mikula, H., Kristensen, Jesper Langgaard, Kjær, Andreas & Herth, Matthias Manfred, 2020, In: Journal of Nuclear Medicine. 61, Supl. 1, 2 p., 134.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  46. Published

    Development of Trans-Cyclooctene Modified Antibodies for Pretargeted Imaging within the Central Nervous System: [Meeting Abstract]

    van den Broek, S. L., Shalgunov, Vladimir, Sehlin, D., Syvanen, S. & Herth, Matthias Manfred, 2020, In: Journal of Nuclear Medicine. 61, Supl. 1, 3 p., 196.

    Research output: Contribution to journal › Conference abstract in journal › Research

  47. Published

    Transport of nanomedicines across the blood-brain barrier: Challenges and opportunities for imaging and therapy

    van den Broek, S. L., Shalgunov, Vladimir & Herth, Matthias Manfred, 2022, In: Biomaterials Advances. 141, 11 p., 213125.

    Research output: Contribution to journal › Review › Research › peer-review

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