Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor, emeritus

ORCID: 0000-0002-1085-8444

Publication year:
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51 - 92 out of 92Page size: 50
  1. 2011
  2. Published

    The hph-1 mouse with inherited deficiency in GTP cyclohydrolase 1 shows reduced inflammatory pain behavior

    Bjerrum, Ole Jannik & Nasser, A., 2011.

    Research output: Contribution to conference › Poster › Research › peer-review

  3. Published

    European new safe and innovative medicines initiatives: history and progress (through December 2009)

    Bjerrum, Ole Jannik & H. Linden, H., Mar 2011, Translational medicine and drug discovery. Cambridge: Cambridge University Press, p. 265-288 23 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  4. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In: European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In: Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., Nov 2011.

    Research output: Contribution to conference › Poster › Communication

  7. 2012
  8. Published

    Blå medicin mod smerter

    Boulakou, A., Bjerrum, Ole Jannik & Honoré, P. G. H., 2012, In: Lægemiddelforskning. 2012, p. 18-19 2 p.

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Kombinationslægemiddel reducerer bivirkningerne ved smertebehandling

    Bjerrum, Ole Jannik, Basnet, A., Honoré, P. G. H. & Gautam, Y., 2012, In: Lægemiddelforskning. 1, p. 15-17 3 p.

    Research output: Contribution to journal › Journal article › Communication

  10. Published

    Sortilins in neuropathic pain

    Richner, M., Bjerrum, Ole Jannik, Koninck, Y. D., Nykjaer, A. & Vaegter, C. B., 29 Dec 2012, In: Scandinavian Journal of Pain. 3, 3, p. 183-184 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. 2013
  12. Published

    Donepezil anvendt ved neuropatisk smerte

    Bjerrum, Ole Jannik & Bjerrum, H. J., 2013, In: Ugesskrift for læger. 175, 42, p. 2493-2494 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Donepezil as add-on to gabapentin for post-traumatic neuropathic pain: an exploratory study

    Basnet, A., Butler, S., Honoré, P. G. H., Butler, M., Gordh, T. E., Kristensen, K. K. & Bjerrum, Ole Jannik, 2013, In: Acta Anaesthesiologica Scandinavica. 58, 1, p. 61-73 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCi-operated rats

    Bjerrum, Ole Jannik, Honoré, P. G. H., Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Gegelashvili, G., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  15. Published

    Dose-dependent effect of ceftriaxone (A beta-lactam) on mechanical pain hypersensitivity in the CCI nerve rat model

    Bjerrum, Ole Jannik, Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Honoré, P. G. H., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  16. Published

    Fixed Dose Combinations. The Physician attitude to the wider use. A pilot study

    Bjerrum, Ole Jannik & Vana, V., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  17. Published

    Fixed drug combinations: are current regulatory guidelines in the EU and US adequate for effectively guiding Development?

    Bjerrum, Ole Jannik, Gautam, Y. & Schmiegelow, M., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  18. Published

    Orphan disease council - A new interdiciplinary private/public partnership promoting the Development of orphan medicinal products

    Bjerrum, Ole Jannik, Hove, H. B., Dali, C., Callesen, L., Ludvig, G. & Thyregod, L., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  19. Published

    Pain perception and Dopa Responsive Dystonia

    Bjerrum, Ole Jannik, Nasser, A., Møller, A. T., Møller, B. & Jensen, T. S., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  20. Published

    Promising effects of donepezil when added to patients treated with gabapentin for neuropathic pain

    Basnet, A., Butler, S., Honoré, P. G. H., Butler, M., Gordh, T. E., Kristensen, K. & Bjerrum, Ole Jannik, 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  21. Published

    Why medicines Combinations? Friend or Foe?

    Bjerrum, Ole Jannik, Gautam, Y., Boonen, H. C. M., Schmiegelow, M. & Honoré, P. G. H., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  22. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie, Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 Feb 2013, In: Molecular Pain. 9, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Medicines combinations options and regulatory hurdles

    Bjerrum, Ole Jannik, Gautam, Y., Bjerrum, E. J., Schmiegelow, M. & Boonen, H. C. M., 16 Jul 2013, In: European Journal of Pharmaceutical Sciences. 49, 4, p. 659-63 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Measurement of sedation in rats. Comparison of the locomotor activity test, open field test and the rotarod test

    Bjerrum, Ole Jannik, Nasser, A., Basnet, A., Merry, A. & Kristensen, P., Nov 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  25. 2014
  26. Published

    Drug-drug combinations revisited

    Bjerrum, Ole Jannik, Gautam, Y., Honoré, P. G. H. & Vana, V., 15 Jan 2014, In: European Journal of Hospital Pharmacy - Science and Practice. 21, 1, p. 8-12 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. 2015
  28. Published

    An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition

    Sawicki-Wrzask, D., Thomsen, M. & Bjerrum, Ole Jannik, 2015, In: Therapeutic Innovation & Regulatory Science. 49, 4, p. 553-559 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    High-affinity Glutamate Transporters in Pain: An Emerging and Therapeutic Target

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2015, In: Journal of Neurochemistry. 6, p. 712-30 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Intraplantar injection of tetrahydrobiopterin induces nociception in mice

    Nasser, A., Ali, S., Wilsbech, S., Bjerrum, Ole Jannik & Birk Møller, L., 2015, In: Neuroscience Letters. 584, p. 247-252 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The wider use of fixed-dose combinations emphasizes the need for a global approach to regulatory guideline development

    Gautam, Y., Bjerrum, Ole Jannik & Schmiegelow, M., 2015, In: Therapeutic Innovation & Regulatory Science. 49, 1, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2016
  33. Published

    A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science: Workshop Proceedings and Commentary

    Borup, G., Bach, K. F., Schmiegelow, M., Kildemoes, H. W., Bjerrum, Ole Jannik & Westergaard, N., May 2016, In: Therapeutic Innovation & Regulatory Science. 50, 3, p. 304-311 8 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  34. 2017
  35. Published

    From Face-to-fase training to blended learning in the postgraduate program SafeSciMet - a case study

    Bjerrum, Ole Jannik, Vos, C., Dragovic, S., Jochimsen, M., Dirac, J., Foth, H. & Wiese, J., 2017, In: European Journal of Pharmaceutical Sciences. 96, p. III-VIII 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and Pharmacology

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 225-253 29 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2018
  39. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

    Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, Anne-Marie & Bjerrum, Ole Jannik, Feb 2018, In: European Journal of Pain. 22, 2, p. 282-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine

    Bjerrum, Ole Jannik & Androlyte, M., Aug 2018, In: Basic & Clinical Pharmacology & Toxicology. 123 , 2, p. 155–160 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2019
  43. Published

    Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA’s and FDA’s Views on Initial Dual-Therapy

    Bjerrum, Ole Jannik, Eichendorff, S. & Alkis, N. B., 2019, In: Therapeutic Innovation & Regulatory Science. 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

    Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, Theis, Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2019, In: British Journal of Clinical Pharmacology. 85, 8, p. 1829-1840 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Community pharmacies as platform for collection of real-world evidence of medicines usage explored through a pilot study: From standard T2D medication to treatment with the injectable combination product Xultophy

    Alkis, N., Nørgaard, Lotte Stig & Bjerrum, Ole Jannik, 2019.

    Research output: Contribution to conference › Poster › Research › peer-review

  46. Published

    Glutamate transport system as a key constituent of glutamosome: Molecular pathology and pharmacological modulation in chronic pain

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2019, In: Neuropharmacology. 161, 107623.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs

    Thoefner, M. S., Westrup, U., Toft, N., Bjerrum, Ole Jannik & Berendt, Mette, 2019, In: Veterinary Journal. 246, p. 92-97 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2020
  49. Published

    Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

    Nøhr-Nielsen, A., Lange, Theis, Forman, Julie Lyng, Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2020, In: The AAPS Journal. 22, 2, 32.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Pregabalin alleviates clinical signs of syringomyelia-related central neuropathic pain in Cavalier King Charles Spaniel dogs: a randomized controlled trial

    Thoefner, M. S., Skovgaard, Lene Theil, McEvoy, Fintan, Berendt, Mette & Bjerrum, Ole Jannik, 2020, In: Veterinary Anaesthesia and Analgesia. 47, 2, p. 238–248

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA's and FDA's Views on Initial Dual-Therapy

    Bjerrum, Ole Jannik, Eichendorff, S. & Alkis, N. B., Mar 2020, In: Therapeutic Innovation & Regulatory Science. 54, 2, p. 297-302 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2022
  53. Published

    Dorsal horn volume loss and pain pathway changes in Cavalier King Charles Spaniels with syringomyelia, signs of pain, and phantom scratching

    Mortensen, D., Thoefner, M. S., Agerholm, Jørgen Steen, Slumstrup, L., Jensen, T. S., Bjerrum, Ole Jannik, Berendt, Mette & Nyengaard, J. R., 2022, In: Pain. 163, 12, p. 2365-2379

    Research output: Contribution to journal › Journal article › Research › peer-review

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