Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. Published

    Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state

    Aduri, N. G., Ernst, H. A., Prabhala, B. K., Bhatt, S., Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2018, In: Biochemical and Biophysical Research Communications. 495, 2, p. 1738-1743 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters

    Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH

    Aduri, N. G., Montefiori, M., Khalil, R., Gajhede, Michael, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 31 Jan 2019, In: ACS Omega. 4, 1, p. 2040-2046 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Rational and combinatorial engineering of the glucan synthesizing enzyme amylosucrase

    Albenne, C., Van Der Veen, B. A., Potocki-Véronèse, G., Joucla, G., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Monsan, P. & Remaud-Simeon, M., 1 Aug 2003, In: Biocatalysis and Biotransformation. 21, 4-5, p. 271-277 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Maltooligosaccharide disproportionation reaction: an intrinsic property of amylosucrase from Neisseria polysaccharea

    Albenne, C., Skov, L. K., Mirza, Osman Asghar, Gajhede, Michael, Potocki-Véronèse, G., Monsan, P. & Remaud-Simeon, M., 11 Sep 2002, In: F E B S Letters. 527, 1-3, p. 67-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Site-directed mutagenesis of key amino acids in the active site of amylosucrase from Neisseria polysaccharea

    Albenne, C., Potocki De Montalk, G., Monsan, P., Skov, L., Mirza, Osman Asghar, Gajhede, Michael & Remaud-Simeon, M., 1 Dec 2002, In: Biologia - Section Cellular and Molecular Biology. 57, SUPPL. 11, p. 119-128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase

    Albenne, C., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Feller, G., D'Amico, S., André, G., Potocki-Véronèse, G., van der Veen, B. A., Monsan, P. & Remaud-Simeon, M., 2 Jan 2004, In: Journal of Biological Chemistry. 279, 1, p. 726-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

    Asghar Butt, S., Søgaard, L. V., Ardenkjaer-Larsen, J. H., Lauritzen, M. H., Engelholm, L. H., Paulson, Olaf B., Mirza, Osman Asghar, Holck, S., Magnusson, P. & Akeson, P., 16 Jan 2015, In: Magnetic Resonance in Medicine. 73, p. 51-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In silico Epitope Prediction and Immunogenic Analysis for Penton base Epitope-focused Vaccine against Hydropericardium syndrome in chicken

    Aziz, F., Tufail, S., Shah, M. A., Salahuddin Shah, M., Habib, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Virus Research. 197750.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Expression, purification and characterization of the human MTA2-RBBP7 complex

    Brasen, C., Dorosz, J., Wiuf, A., Boesen, T., Mirza, Osman Asghar & Gajhede, Michael, 4 Feb 2017, In: Biochimica et biophysica acta. 1865, 5, p. 531-538 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

    Champion, E., Remaud-Simeon, M., Skov, L. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 12, p. 1309-1314

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides

    Ernst, H. A., Pham, A., Hald, H., Kastrup, Jette Sandholm Jensen, Rahman, M. & Mirza, Osman Asghar, 2009, In: Biochemical and Biophysical Research Communications. 389, 1, p. 112-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

    Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, M., Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In: PLoS ONE. 14, 5, 15 p., e0217292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Functional Characterization of the Putative POT from Clostridium perfringens

    Gharabli, H., Rafiq, M., Iqbal, A., Yan, R., Aduri, N. G., Sharma, N., Prabhala, B. K. & Mirza, Osman Asghar, 2023, In: Biology. 12, 5, 11 p., 651.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structural determination of wild-type lactose permease

    Guan, L., Mirza, Osman Asghar, Verner, G., Iwata, S. & Kaback, H. R., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 39, p. 15294-15298

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign

    Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  19. Published

    Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization

    Hameed, U., Price, I., Ikram-Ul-Haq, Ke, A., Wilson, D. B. & Mirza, Osman Asghar, Oct 2017, In: B B A - Proteins and Proteomics. 1865, 10, p. 1237-1245 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions

    Henriksen, A., Mirza, Osman Asghar, Indiani, C., Teilum, Kaare, Smulevich, G., Welinder, K. G. & Gajhede, Michael, 2001, In: Protein Science. 10, 1, p. 108-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily

    Henriksen, A., King, T. P., Mirza, Osman Asghar, Monsalve, R. I., Meno, K., Ipsen, H., Larsen, J. N., Gajhede, M. & Spangfort, M. D., 2001, In: Proteins: Structure, Function, and Bioinformatics. 45, 4, p. 438-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Functional investigation of conserved membrane-embedded glutamate residues in the proton-coupled peptide transporter YjdL

    Jensen, J. M., Ernst, H. A., Wang, X., Hald, H., Ditta, A. C., Ismat, F., Rahman, M. & Mirza, Osman Asghar, Mar 2012, In: Protein and Peptide Letters. 19, 3, p. 282-287

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Probing the putative active site of YjdL: an unusual proton-coupled oligopeptide transporter from E. coli

    Jensen, J. M., Ismat, F., Szakonyi, G., Rahman, M. & Mirza, Osman Asghar, 2012, In: P L o S One. 7, 10, p. e47780

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biophysical characterization of the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Simonsen, F. C., Mastali, A., Hald, H., Lillebro, I., Diness, Frederik, Olsen, L. & Mirza, Osman Asghar, Nov 2012, In: Peptides. 38, 1, p. 89-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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