Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. 2019
  2. Published

    In silico Epitope Prediction and Immunogenic Analysis for Penton base Epitope-focused Vaccine against Hydropericardium syndrome in chicken

    Aziz, F., Tufail, S., Shah, M. A., Salahuddin Shah, M., Habib, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Virus Research. 197750.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Restraining the multidrug efflux transporter STY4874 of Salmonella Typhi by reserpine and plant extracts

    Tariq, A., Sana, M., Shaheen, A., Ismat, F., Mahboob, S., Rauf, W., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Letters in Applied Microbiology. 69, 3, p. 161-167

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

    Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, M., Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In: PLoS ONE. 14, 5, 15 p., e0217292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state

    Aduri, N. G., Ernst, H. A., Prabhala, B. K., Bhatt, S., Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2018, In: Biochemical and Biophysical Research Communications. 495, 2, p. 1738-1743 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

    Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, Paul Robert, Brasen, C., Gajhede, Michael, Rahman, M. & Mirza, Osman Asghar, 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization

    Hameed, U., Price, I., Ikram-Ul-Haq, Ke, A., Wilson, D. B. & Mirza, Osman Asghar, Oct 2017, In: B B A - Proteins and Proteomics. 1865, 10, p. 1237-1245 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structural Biology Meets Drug Resistance: An Overview on Multidrug Resistance Transporters

    Shaheen, A., Iqbal, M., Mirza, Osman Asghar & Rahman, M., 1 Jun 2017, In: Journal of the Indian Institute of Science. 97, 2, p. 165-175 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Anandamide and 2-AG Are Endogenously Present within the Laterodorsal Tegmental Nucleus: Functional Implications for a role of eCBs in arousal

    Soni, N., Prabhala, B. K., Mehta, V., Mirza, Osman Asghar & Kohlmeier, Kristi Anne, Jun 2017, In: Brain Research. 1665, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

    Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Expression, purification and characterization of the human MTA2-RBBP7 complex

    Brasen, C., Dorosz, J., Wiuf, A., Boesen, T., Mirza, Osman Asghar & Gajhede, Michael, 4 Feb 2017, In: Biochimica et biophysica acta. 1865, 5, p. 531-538 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]

    Jørgensen, M. E., Xu, Deyang, Crocoll, C., Ernst, H. A., Ramírez, D., Motawie, Mohammed Saddik, Olsen, C. E., Mirza, Osman Asghar, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2017, In: eLife. 6, 30 p., e19466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2016
  17. Published

    Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production

    Ullah, R., Shah, M. A., Tufail, S., Ismat, F., Imran, M., Iqbal, M., Mirza, Osman Asghar & Rhaman, M., 2016, In: PloS one. 11, 4, 13 p., e0153436.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Peptide Selectivity of the Proton-Coupled Oligopeptide Transporter from Neisseria meningitidis

    Sharma, N., Aduri, N. G., Iqbal, A., Prabhala, B. K. & Mirza, Osman Asghar, 2016, In: Journal of Molecular Microbiology and Biotechnology. 26, 5, p. 312-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2015
  20. Published

    Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

    Asghar Butt, S., Søgaard, L. V., Ardenkjaer-Larsen, J. H., Lauritzen, M. H., Engelholm, L. H., Paulson, Olaf B., Mirza, Osman Asghar, Holck, S., Magnusson, P. & Akeson, P., 16 Jan 2015, In: Magnetic Resonance in Medicine. 73, p. 51-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A functional EXXEK motif is essential for proton coupling and active glucosinolate transport by NPF2.11

    Jørgensen, M. E., Olsen, C. E., Geiger, D., Mirza, Osman Asghar, Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2015, In: Plant and Cell Physiology. 56, 12, p. 2340-2350 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Characterization of putative multidrug resistance transporters of the major facilitator-superfamily expressed in Salmonella Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., De Zorzi, R., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2015, In: Journal of Infection and Chemotherapy. 21, 5, p. 357–362 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Characterization of synthetic peptides by mass spectrometry

    Prabhala, B. K., Mirza, Osman Asghar, Højrup, P. & Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Investigation of the substrate specificity of the proton coupled peptide transporter PepTSo from Shewanella oneidensis

    Prabhala, B. K., Aduri, N. G., Hald, H. & Mirza, Osman Asghar, 2015, In: International Journal of Peptide Research and Therapeutics. 15, 21, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters

    Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2014
  27. Published

    Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    New insights into the substrate specificities of proton-coupled oligopeptide transporters from E. coli by a pH sensitive assay

    Prabhala, B. K., Aduri, N. G., Jensen, J. M., Ernst, H. A., Iram, N., Rahman, M. & Mirza, Osman Asghar, 16 Jan 2014, In: FEBS Letters. 588, 4, p. 560-565

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2013
  30. Published

    The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology

    Skov, L. K., Pizzut-Serin, S., Remaud-Simeon, M., Ernst, H. A., Gajhede, Michael & Mirza, Osman Asghar, Sep 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, Pt 9, p. 973-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2012
  32. Published

    Biophysical characterization of the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Simonsen, F. C., Mastali, A., Hald, H., Lillebro, I., Diness, Frederik, Olsen, L. & Mirza, Osman Asghar, Nov 2012, In: Peptides. 38, 1, p. 89-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Functional investigation of conserved membrane-embedded glutamate residues in the proton-coupled peptide transporter YjdL

    Jensen, J. M., Ernst, H. A., Wang, X., Hald, H., Ditta, A. C., Ismat, F., Rahman, M. & Mirza, Osman Asghar, Mar 2012, In: Protein and Peptide Letters. 19, 3, p. 282-287

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302772