Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. 2007
  2. Published

    Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains

    Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2008
  4. Published

    Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter

    Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, Osman Asghar, Krusong, K., Carpenter, E. P., Rutherford, N. G., Hadden, J. M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S. G., Hope, R. J., Norbertczak, H. T., Roach, P. C. J., Iwata, S., Henderson, P. J. F. & Cameron, A. D., 2008, In: Science. 322, 5902, p. 709-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit

    Paës, G., Skov, L. K., O'Donohue, M. J., Rémond, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2008, In: Biochemistry. 47, 28, p. 7441-7451

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2009
  8. Published

    Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides

    Ernst, H. A., Pham, A., Hald, H., Kastrup, Jette Sandholm Jensen, Rahman, M. & Mirza, Osman Asghar, 2009, In: Biochemical and Biophysical Research Communications. 389, 1, p. 112-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

    Champion, E., Remaud-Simeon, M., Skov, L. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 12, p. 1309-1314

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2010
  11. Published

    Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

    Wang, X., Hald, H., Ernst, H. A., Egebjerg, J., Christensen, K. V., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Mirza, Osman Asghar, 2010, In: Protein Expression and Purification. 71, 2, p. 179-183

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign

    Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  13. 2012
  14. Published

    Probing the putative active site of YjdL: an unusual proton-coupled oligopeptide transporter from E. coli

    Jensen, J. M., Ismat, F., Szakonyi, G., Rahman, M. & Mirza, Osman Asghar, 2012, In: P L o S One. 7, 10, p. e47780

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Functional investigation of conserved membrane-embedded glutamate residues in the proton-coupled peptide transporter YjdL

    Jensen, J. M., Ernst, H. A., Wang, X., Hald, H., Ditta, A. C., Ismat, F., Rahman, M. & Mirza, Osman Asghar, Mar 2012, In: Protein and Peptide Letters. 19, 3, p. 282-287

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biophysical characterization of the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Simonsen, F. C., Mastali, A., Hald, H., Lillebro, I., Diness, Frederik, Olsen, L. & Mirza, Osman Asghar, Nov 2012, In: Peptides. 38, 1, p. 89-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2013
  18. Published

    The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology

    Skov, L. K., Pizzut-Serin, S., Remaud-Simeon, M., Ernst, H. A., Gajhede, Michael & Mirza, Osman Asghar, Sep 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, Pt 9, p. 973-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2014
  20. Published

    New insights into the substrate specificities of proton-coupled oligopeptide transporters from E. coli by a pH sensitive assay

    Prabhala, B. K., Aduri, N. G., Jensen, J. M., Ernst, H. A., Iram, N., Rahman, M. & Mirza, Osman Asghar, 16 Jan 2014, In: FEBS Letters. 588, 4, p. 560-565

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2015
  23. Published

    A functional EXXEK motif is essential for proton coupling and active glucosinolate transport by NPF2.11

    Jørgensen, M. E., Olsen, C. E., Geiger, D., Mirza, Osman Asghar, Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2015, In: Plant and Cell Physiology. 56, 12, p. 2340-2350 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Characterization of putative multidrug resistance transporters of the major facilitator-superfamily expressed in Salmonella Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., De Zorzi, R., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2015, In: Journal of Infection and Chemotherapy. 21, 5, p. 357–362 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Characterization of synthetic peptides by mass spectrometry

    Prabhala, B. K., Mirza, Osman Asghar, Højrup, P. & Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Investigation of the substrate specificity of the proton coupled peptide transporter PepTSo from Shewanella oneidensis

    Prabhala, B. K., Aduri, N. G., Hald, H. & Mirza, Osman Asghar, 2015, In: International Journal of Peptide Research and Therapeutics. 15, 21, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters

    Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

    Asghar Butt, S., Søgaard, L. V., Ardenkjaer-Larsen, J. H., Lauritzen, M. H., Engelholm, L. H., Paulson, Olaf B., Mirza, Osman Asghar, Holck, S., Magnusson, P. & Akeson, P., 16 Jan 2015, In: Magnetic Resonance in Medicine. 73, p. 51-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2016
  30. Published

    Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production

    Ullah, R., Shah, M. A., Tufail, S., Ismat, F., Imran, M., Iqbal, M., Mirza, Osman Asghar & Rhaman, M., 2016, In: PloS one. 11, 4, 13 p., e0153436.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Peptide Selectivity of the Proton-Coupled Oligopeptide Transporter from Neisseria meningitidis

    Sharma, N., Aduri, N. G., Iqbal, A., Prabhala, B. K. & Mirza, Osman Asghar, 2016, In: Journal of Molecular Microbiology and Biotechnology. 26, 5, p. 312-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2017
  33. Published

    Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]

    Jørgensen, M. E., Xu, Deyang, Crocoll, C., Ernst, H. A., Ramírez, D., Motawie, Mohammed Saddik, Olsen, C. E., Mirza, Osman Asghar, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2017, In: eLife. 6, 30 p., e19466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Expression, purification and characterization of the human MTA2-RBBP7 complex

    Brasen, C., Dorosz, J., Wiuf, A., Boesen, T., Mirza, Osman Asghar & Gajhede, Michael, 4 Feb 2017, In: Biochimica et biophysica acta. 1865, 5, p. 531-538 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

    Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302772