Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. Published

    Investigation of the substrate specificity of the proton coupled peptide transporter PepTSo from Shewanella oneidensis

    Prabhala, B. K., Aduri, N. G., Hald, H. & Mirza, Osman Asghar, 2015, In: International Journal of Peptide Research and Therapeutics. 15, 21, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1

    Rafiq, M., Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, Magnus Borup, Mirza, N., Taylor, Nicholas M I, Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2022, In: Protein Expression and Purification. 190, 7 p., 105990.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Expression of ESAT-6 antigen from Mycobacterium tuberculosis in broccoli: An edible plant

    Saba, K., Sameeullah, M., Asghar, A., Gottschamel, J., Latif, S., Lössl, A. G., Mirza, B., Mirza, Osman Asghar & Waheed, M. T., 2020, In: Biotechnology and Applied Biochemistry. 67, 1, p. 148-157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

    Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

    Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Accepted/In press

    The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

    Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Reserpine Is the New Addition into the Repertoire of AcrB Efflux Pump Inhibitors

    Shaheen, A., Afridi, W. A., Mahboob, S., Sana, M., Zeeshan, N., Ismat, F., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 10 Aug 2019, In: Molecular Biology. 53, 4, p. 674-684 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

    Shaheen, A., Tariq, A., Iqbal, M., Mirza, Osman Asghar, Haque, A., Walz, T. & Rahman, M., 2021, In: Antibiotics. 10, 12, 26 p., 1455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structural Biology Meets Drug Resistance: An Overview on Multidrug Resistance Transporters

    Shaheen, A., Iqbal, M., Mirza, Osman Asghar & Rahman, M., 1 Jun 2017, In: Journal of the Indian Institute of Science. 97, 2, p. 165-175 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Accepted/In press

    Identification of additional mechanistically important residues in the multidrug transporter styMdtM of Salmonella Typhi

    Shaheen, A., Tariq, A., Ismat, F., Naveed, H., De Zorzi, R., Iqbal, M., Storici, P., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2023, (Accepted/In press) In: Journal of Biomolecular Structure and Dynamics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Characterization of the multidrug efflux transporter styMdtMfrom Salmonella enterica serovar Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., Ul-Haq, Z., Mirza, Osman Asghar, De Zorzi, R., Walz, T. & Rahman, M., 2021, In: Proteins: Structure, Function, and Bioinformatics. 89, 9, p. 1193-1204

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Transcriptional regulation of drug resistance mechanisms in Salmonella: where we stand and what we need to know

    Shaheen, A., Tariq, A., Shehzad, A., Iqbal, M., Mirza, Osman Asghar, Maslov, D. A. & Rahman, M., 2020, In: World journal of microbiology & biotechnology. 36, 6, 8 p., 85.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Characterization of putative multidrug resistance transporters of the major facilitator-superfamily expressed in Salmonella Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., De Zorzi, R., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2015, In: Journal of Infection and Chemotherapy. 21, 5, p. 357–362 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Peptide Selectivity of the Proton-Coupled Oligopeptide Transporter from Neisseria meningitidis

    Sharma, N., Aduri, N. G., Iqbal, A., Prabhala, B. K. & Mirza, Osman Asghar, 2016, In: Journal of Molecular Microbiology and Biotechnology. 26, 5, p. 312-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Crystallization and preliminary X-ray studies of recombinant amylosucrase from Neisseria polysaccharea

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., Potocki de Montalk, G., Remaud-Simeon, M., Sarcabal, P., Willemot, R. M., Monsan, P. & Gajhede, M., Feb 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 2, p. 203-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., De Montalk, G. P., Remaud-Simeon, M., Sarçabal, P., Willemot, R. M., Monsan, P. & Gajhede, Michael, 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 25273-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., Dar, I., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 6 Dec 2002, In: Journal of Biological Chemistry. 277, 49, p. 47741-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology

    Skov, L. K., Pizzut-Serin, S., Remaud-Simeon, M., Ernst, H. A., Gajhede, Michael & Mirza, Osman Asghar, Sep 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, Pt 9, p. 973-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., van der Veen, B., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 1 Jan 2006, In: Biocatalysis and Biotransformation. 24, 1-2, p. 99-105 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Anandamide and 2-AG Are Endogenously Present within the Laterodorsal Tegmental Nucleus: Functional Implications for a role of eCBs in arousal

    Soni, N., Prabhala, B. K., Mehta, V., Mirza, Osman Asghar & Kohlmeier, Kristi Anne, Jun 2017, In: Brain Research. 1665, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment

    Spangfort, M. D., Mirza, Osman Asghar & Gajhede, Michael, Dec 1999, In: Acta Crystallographica. Section D: Biological Crystallography. 55, Pt 12, p. 2035-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis

    Spangfort, M. D., Mirza, Osman Asghar, Ipsen, H., Van Neerven, R. J. J., Gajhede, Michael & Larsen, J., 2003, In: Journal of Immunology. 171, 6, p. 3084-90 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

    Sprogøe, D., van den Broek, L. A. M., Mirza, Osman Asghar, Kastrup, Jette Sandholm Jensen, Voragen, A. G. J., Gajhede, Michael & Skov, L., 10 Feb 2004, In: Biochemistry. 43, 5, p. 1156-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains

    Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection

    Tanabe, M., Atkins, H. S., Harland, D. N., Elvin, S. J., Stagg, A. J., Mirza, Osman Asghar, Titball, R. W., Byrne, B. & Brown, K. A., Jun 2006, In: Infection and Immunity. 74, 6, p. 3687-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302772