Paul Robert Hansen

Paul Robert Hansen

Associate Professor


  1. 2023
  2. Published

    N-acetylcysteine-chitosan nanoparticles with the Ctx(Ile21)-Ha peptide grafted onto the surface can rescue the susceptibility of pre-extensively resistant Mycobacterium tuberculosis

    Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2 Oct 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  3. Published

    Rifampicin-loaded N-acetylcysteine-chitosan nanoparticles surface-grafted with a peptide exhibit potent activity against multidrug-resistant Mycobacterium tuberculosis

    Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 11 Jun 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  4. Published

    The effect of Cys15 and Cys21 replacement with Ala, Ser and Lys on the anti Mycobacterium tuberculosis activity of antimicrobial peptide B1CTcu5

    Roque-Borda, C. A., Costa de Pontes, J. T., Domingos da Silva, L. H., Caroline dos Santos, I. C. D. S., Aparecida Resende, F., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2023.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  5. 2018
  6. Published

    Fmoc Solid-Phase Synthesis of Human a-Calcitonin Gene- Related Peptide and Two Carboxyfluorescein-labeled Analogs

    Ahmed, L. S., Abdolalizadeh, B., Sheykhzade, Majid & Hansen, Paul Robert, 11 Feb 2018.

    Research output: Contribution to conferencePosterResearchpeer-review

  7. 2017
  8. Published

    Structure-activity relationship studies of lysine-based α-peptide/β-peptoid antimicrobial peptidomimetics

    Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2017. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. 2016
  10. Published
  11. 2015
  12. Published

    Solid-Phase Peptide Synthesis of Human alfa-Calcitonin Gene-Related Peptide and Two Fluorescent Analogs.

    Fuente-Moreno, M., Oddo, A., Sheykhzade, Majid, Pickering, Darryl S & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium . 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  13. Published

    Novel classes of antimicrobials in veterinary medicine: Characterizing peptoids as topical agents for dog skin infections

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Vasir, J., Watts, J., Hummel, B. D. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Novel compounds with selective antimicrobial activity against Staphylococcus pseudintermedius and Pseudomonas aeruginosa causing pyoderma in dogs

    Greco, I., Emborg, A., Oddo, A., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    Short linear peptide-peptoid hybrids as potential antimicrobial drugs: Abstract for the 24th American Peptide Symposium

    Greco, I., Damborg, Peter Panduro, Jana, B. & Hansen, Paul Robert, 1 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Structure-Activity Relationship Study of Lysine-Based Antimicrobial α-Peptide/β-Peptoid Oligomers

    Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 2015.

    Research output: Contribution to conferencePosterResearch

  17. Published

    An ANOVA-based model to identify the optimal antimicrobial peptide in a combination matrix

    Munk, J. K., Ritz, C., Fliedner, F. P., Frimodt-Moller, N. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. Published

    Antimicrobial activities of synthetic anoplin analogues against methicillin-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus faecium and Candida albicans

    Munk, J. K., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Moller, N., Nyberg, N., Wimmer, R. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  19. Published

    Identifying immunogenic CD4+ T-cell epitopes of Myeloid cell leukemia 1 using overlapping 20-mer peptides spanning the whole protein.

    Woodworth, J. S., Agger, E. M. & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium Ved Srivastava, Andrei Yudin, and Michal Lebl (Editors) American Peptide Society. p. 262-63 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  20. 2014
  21. Published
  22. Published

    Invited Lecture: From Host Defence Peptides to New Antibiotics

    Hansen, Paul Robert, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  23. Published

    Ring flexibility as a key design feature for cyclic antimicrobial peptides

    Oddo, A., Frimodt-Møller, N. & Hansen, Paul Robert, 4 Jun 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  24. 2013
  25. Published

    A Novel Peptide-Peptoid Hybrid Active Against MRSP Skin Infections

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 4 Nov 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  26. Published
  27. Published

    A Minimal Labor Approach to Identifying the Optimal Anoplin Analog using ANOVA.

    Munk, J., Ritz, C., Petrine Fliedner, F., Frimodt-Møller, N. & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  28. Published

    The Structure of the Central Side Chain is Crucial for Anoplin Hemolytic Activity

    Munk, J., Thøgersen, L., Uggerhøj, L. E., Wimmer, R., Frimodt-Møller, N., Lindorff-Larsen, Kresten & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium. Lebl, M. (ed.). American Peptide Society

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  29. Published

    De novo design of novel cyclic antimicrobial peptides

    Oddo, A., Frimodt-Moller, N. & Hansen, Paul Robert, 7 Jul 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  30. 2012
  31. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, Peter Panduro, Skindersø, M. E., Hansen, Paul Robert, Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, Luca, Aug 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. 2011
  33. Published
  34. Published

    Peptoid inhibits essential cellular functions through unspecific binding to DNA in S. aureus

    Gottschalk, S., Søndergaard, S. L., Hansen, Paul Robert, Ifrah, D., Ingmer, Hanne & Thomsen, Line Elnif, 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Use of resin-bound peptides for epitope mapping of a monoclonal anti-gliadin antibody related to celiac disease

    Petersen, N. H., Hansen, Paul Robert & Houen, G., 25 Jun 2011.

    Research output: Contribution to conferencePosterResearch

  36. Published

    Identification of linear epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

    Trier, N. H., Hansen, Paul Robert & Houen, G., 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  37. 2010
  38. Published

    Antimicrobial activity of small 3-(2 naphthyl)-L-alanine containing peptides

    Hansen, Paul Robert & Frimodt-Møller, N., 2010, In: Proceedings of the 31st European Peptide Symposium,. 2 p.

    Research output: Contribution to journalConference articleResearch

  39. Published

    Jelleine-I analogues with improved antibacterial activity

    Hansen, Paul Robert, 2010, Peptides - Copenhagen 2010, tales of peptides: proceedings of the 31th European Peptide Symposium. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 376-377 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  40. Published

    Jelleine-I analogues with increased antibacterial activity

    Hansen, Paul Robert, Petersen, Jette & Andresen, S., 2010.

    Research output: Contribution to conferencePosterResearch

  41. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  42. 2009
  43. Published

    A combinatorial approach to identify novel peptide targeted against the cancer specific receptor mutation, EFGRvIII.

    Denholdt, C., Hansen, Paul Robert, Pedersen, N., Skovgaard Poulsen, H., Gillings, N. & Kjær, A., 2009.

    Research output: Contribution to conferencePosterResearch

  44. Published

    Peptoid analogs of the antibacterial peptide anoplin

    Meinike, K. & Hansen, Paul Robert, 2009.

    Research output: Contribution to conferencePosterResearch

  45. Published

    Trypsin stability of lysine-peptoid hybrids

    Ryge, T. S. & Hansen, Paul Robert, 2009, Peptides for youth: the proceedings of the 20. American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 581-582 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  46. Published

    Fallaxin analogues with improved antibacterial activity

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2009, Peptides for Youth: the proceedings of the 20th American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 531-532 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  47. 2008
  48. Published

     Impact of newly synthesized antimicrobial peptides on Staphylococcus aureus

    Gottschalk, S., Søndergaard, S. L., Hansen, Paul Robert, Ingmer, Hanne & Thomsen, Line Elnif, 2008. 1 p.

    Research output: Contribution to conferencePosterResearch

  49. Published

    Antibacterial activity of a human lysozyme C-terminal fragment conjugated to lipophilic acids

    Ifrah, D. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  50. Published

    Design, Synthesis and Characterization of Novel Antibacterial Lysine-Peptoid Hybrids

    Neerup, T. S. R. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  51. Published

     Antimicrobial activities of Lysine-Peptoid Hybrids against Clinically Relevant Bacteria and Fungi

    Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  52. Published

    Fallaxin: Correlation of antibacterial activity with mean hydrophobicity <H> and mean hydrophobic moment <µ>

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  53. 2007
  54. Published

    Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabelling agents of PEPHC1 for PET imaging of EGFRvIII

    Hansen, C. L., Kuhnast, B., Hinnen, F., Gillings, N., Hansen, Paul Robert, Kjær, A. & Dolle, F., 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  55. Published

    Development of 18F-labelled EGFRvIII targeting peptides

    Hansen, C. L., Kuhnast, B., Pedersen, N., Hinnen, F., Poulsen, H. S., Gillings, N., Hansen, Paul Robert, Kjær, A. & Dolle, F., 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  56. Published

    Trypsin stability of lysine-peptoid hybrids

    Neerup, T. S. R. & Hansen, Paul Robert, 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  57. Published

    Fallaxin: optimization of cleavage conditions following solid-phase synthesis

    Søndergaard, S. L., Hansen, Paul Robert & Christensen, U., 2007, Ikke angivet. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, p. 498-499 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  58. Published

    Fallaxin analogues with improved antibacterial activity

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  59. 2006
  60. Published

    Single Amino Acid Substitution Analogues of The  Antibacterial Peptide [A7]-Anoplin

    Hansen, Paul Robert, Ifrah, D., Lianee, H., Thing, C. S. & Vitved, T., 2006.

    Research output: Contribution to conferencePosterResearch

  61. Published

    Single amino acid substitution analogues of the antibacterial peptide [A7]-anoplin

    Hansen, Paul Robert, Ifrah, D., Lianee, H. T., Thing, C. S. & Vitved, T., 2006, Peptides 2006: proceedings of the twenty-ninth European Peptide Symposium. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, p. 284-285 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  62. Published

    Identification of antibacterial lysine-peptoid hybrids using a mixture-based combinatorial library

    Ryge, T. S. & Hansen, Paul Robert, 2006. 4 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  63. Published

    Fallaxin: Optimization of cleavage conditions following solid-phase synthesis

    Søndergaard, S. L., Christensen, U. & Hansen, Paul Robert, 2006.

    Research output: Contribution to conferencePosterResearch

  64. 2005
  65. Published

    Synthesis and raman spectroscopic studies of the antimicrobial peptide cecropin B2

    Ladefoged Nielsen, S., Doisy, X., Hansen, Paul Robert & Faurskov Nielsen, O., 2005.

    Research output: Contribution to conferencePosterResearch

  66. Published

    Antibacterial lysine-peptoid hybrids with selective cytolytic activity

    Neerup, T. S. R. & Hansen, Paul Robert, 2005.

    Research output: Contribution to conferencePosterResearch

  67. 2004
  68. Published

    Analogues of the antibacterial peptide RRWWRF-NH2

    Hansen, Paul Robert, Neerup, T. S. R. & Ifrah, D., 2004.

    Research output: Contribution to conferencePosterResearch

  69. Published

    Ala-scan study of the antibacterial peptide anoplin

    Ifrah, D., Neerup, T. S. R. & Hansen, Paul Robert, 1 Sep 2004.

    Research output: Contribution to conferencePosterResearch

  70. Published

    Antibacterial activity of a human lysozyme C-terminal fragment conjugated to lipophilic acids

    Ifrah, D. & Hansen, Paul Robert, 2004. 3 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  71. Published

    Qualitative study of the alanine-scan of anoplin

    Ifrah, D., Ryge, T. S. & Hansen, Paul Robert, 2004. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  72. Published

    N-Derivatized Analogues of Indolicidin and [Phe4,6,8,9,11] Indolicidin with Enhanced Antibacterial Activity

    Neerup, T. S. R. & Hansen, Paul Robert, 2004.

    Research output: Contribution to conferencePosterResearch

  73. Published

    N-terminal derivatized analogues of indolicidin and [Phe4,6,8,9,11]indolicidin with enhanced antibacterial activity

    Ryge, T. S. & Hansen, Paul Robert, 2004. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  74. Published

    Design, synthesis and characterization of novel antibacterial lysine-peptoid hybrids

    Ryge, T. S. & Hansen, Paul Robert, 2004. 4 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  75. 2003
  76. Published

    Small analogues of lysozyme with antibacterial properties

    Doisy, X., Ifrah, D., Neerup, T. S. & Hansen, Paul Robert, 2003. 2 p.

    Research output: Contribution to conferencePaperResearch

  77. Published

    Small analogues of lysozyme with antibacterial properties

    Doisy, X., Ifrah, D., Neerup, T. S. & Hansen, Paul Robert, 2003.

    Research output: Contribution to conferencePosterResearch

  78. Published

    Indolicidin analogs with potent antibacterial activity

    Neerup, T. S., Doisy, X., Ifrah, D. & Hansen, Paul Robert, 2003, Ikke angivet. Michael Chorev, T. K. S. E. (ed.). American Peptide Society, p. 940-941 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  79. Published

    Indolicidin analogues with potent antibacterial activity

    Neerup, T. S., Doisy, X., Ifrah, D. & Hansen, Paul Robert, 2003.

    Research output: Contribution to conferencePosterResearch

  80. 2002
  81. Published

    Evaluation of Primary Amines for Peptoid Synthesis and Evaluation of byproducts using LC-MS

    Hansen, Paul Robert, 2002.

    Research output: Contribution to conferencePosterResearch

  82. Published

    Evaluation of primary amines for peptoid synthesis and identification of byproducts using LC-MS

    Neerup, T. S., Doisy, X. & Hansen, Paul Robert, 2002. 2 p.

    Research output: Contribution to conferencePaperResearch

  83. 1998
  84. Published

    A ¤new strategy for the synthesis of neoglycopeptides based on maleimido-thiol chemistry

    Hansen, Paul Robert, Heron, I., Olsen, C. E., Jakobsen, M. H. & Holm, A., 1998, Ikke angivet. Ramage, R. & Epton, R. (eds.). Mayflower Scientific, p. 457-458 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

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