Petrine Wellendorph

Petrine Wellendorph

Professor

ORCID: 0000-0002-5455-8013

Publication year:
All
51 - 75 out of 100Page size: 25
  1. 2017
  2. Published

    Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke

    Lie, M. E. K., Al-Khawaja, A., Damgaard, M., Haugaard, A. S., Schousboe, Arne, Clarkson, A. N. & Wellendorph, Petrine, 2017, Advances in Neurobiology. Vol. 16. p. 137-167 31 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  3. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, C. B., Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    gamma-Aminobutyric Acid and Glycine Neurotransmitter Transporters

    Wellendorph, Petrine, Jacobsen, Julie, Skovgaard-Petersen, J., Jurik, A., Vogensen, S. B., Ecker, G., Schousboe, Arne, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 2017, Transporters As Drug Targets.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  5. 2016
  6. Published

    Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using (3)H-HOCPCA

    Klein, A. B., Bay, T., Villumsen, I. S., Falk-Petersen, C. B., Marek, A., Frølund, Bente, Clausen, Rasmus Prætorius, Hansen, H. D., Knudsen, Gitte Moos & Wellendorph, Petrine, Nov 2016, In: Neurochemistry International. 100, p. 138-145 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Radiosynthesis and characterisation of a potent and selective GPR139 agonist radioligand

    Kuhne, S., Nøhr, A. C., Marek, A., Elbert, T., Klein, A. B., Bräuner, Hans, Wellendorph, Petrine & Pedersen, D. S., 2016, In: RSC Advances. 6, 2, p. 947-952 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2015
  9. Published

    Demonstration of the dynamic mass redistribution label-free technology as a useful cell-based pharmacological assay for endogenously expressed GABAA receptors

    Klein, A. B., Nittegaard-Nielsen, M., Christensen, J. T., Al-Khawaja, A. & Wellendorph, Petrine, 19 Nov 2015, In: MedChemComm. 7, p. 426-432 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Identification of the first highly selective inhibitor of human GABA transporter GAT3

    Damgaard, M., Al-Khawaja, A., Vogensen, S. B., Jurik, A., Sijm, M., Lie, M., Bæk, M. I., Rosenthal, E., Jensen, Anders A., Ecker, G. F., Frølund, Bente, Wellendorph, Petrine & Clausen, Rasmus Prætorius, 2015, In: A C S Chemical Neuroscience. 6, p. 1591-1599 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    In vitro and in vivo evidence for active brain uptake of the GHB analogue HOCPCA by the monocarboxylate transporter subtype 1

    Thiesen, L., Kehler, J., Clausen, Rasmus Prætorius, Frølund, Bente, Bundgaard, C. & Wellendorph, Petrine, 2015, In: Journal of Pharmacology and Experimental Therapeutics. 354, 2, p. 166-174 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes

    Villumsen, I. S., Wellendorph, Petrine & Smart, T. G., 2015, In: BMC Neuroscience. 16, 8, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2014
  14. Published

    Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin

    Eghorn, L. F., Høstgaard-Jensen, K., Kongstad, Kenneth Thermann, Bay, T., Higgins, D., Frølund, Bente & Wellendorph, Petrine, 5 Oct 2014, In: European Journal of Pharmacology. 740, p. 570-577 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

    Al-Khawaja, A. M. A., Petersen, J. G., Damgaard, M., Jensen, M. H., Vogensen, S. B., Lie, M. E. K., Kragholm, B., Bräuner, Hans, Clausen, Rasmus Prætorius, Frølund, Bente & Wellendorph, Petrine, 23 May 2014, In: Neurochemical Research. 39, 10, p. 1988-1996 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    GHB receptor targets in the CNS: Focus on high-affinity binding sites

    Bay, T., Eghorn, L. F., Klein, A. B. & Wellendorph, Petrine, 2014, In: Biochemical Pharmacology. 87, 2, p. 220-228 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Promiscuous Seven Transmembrane Receptors Sensing L-α-amino Acids

    Smajilovic, S., Wellendorph, Petrine & Bräuner, Hans, 2014, In: Current Pharmaceutical Design. 20, p. 2693-702 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The G protein-coupled receptor, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function

    Clemmensen, Christoffer, Smajilovic, S., Wellendorph, Petrine & Bräuner, Hans, 2014, In: British Journal of Pharmacology. 171, 5, p. 1129-1141

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2013
  20. Published

    Delineation of the GPRC6A Receptor Signaling Pathways Using a Mammalian Cell Line Stably Expressing the Receptor

    Jacobsen, S. E., Nørskov-Lauritsen, L., Thomsen, A. R. B., Smajilovic, S., Wellendorph, Petrine, Larsson, N. H. P., Lehmann, A., Bhatia, V. K. & Bräuner, Hans, Nov 2013, In: Journal of Pharmacology and Experimental Therapeutics. 347, 2, p. 298-309 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties

    Jensen, Anders A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, Petrine, Stensbøl, T. B., Gloriam, David E., Krogsgaard-Larsen, Povl & Frølund, Bente, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1211-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Selective mGAT2 (BGT-1) GABA Uptake Inhibitor: Design, synthesis and pharmacological characterization

    Vogensen, S. B., Jørgensen, L., Madsen, K. K., Borkar, N. N., Wellendorph, Petrine, Skovgaard-Petersen, J., Schousboe, Arne, White, H. S., Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 11 Feb 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 2160-2164 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites

    Vogensen, S. B., Marek, A., Bay, T., Wellendorph, Petrine, Kehler, J., Bundgaard, C., Frølund, Bente, Pedersen, M. H. F. & Clausen, Rasmus Prætorius, 2013, In: Journal of Medicinal Chemistry. 56, 20, p. 8201–8205

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

    Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2012
  26. Published

    Low nanomolar GABA effects at extrasynaptic a4ß1/ß3delta GABAA receptor subtypes indicate a different binding mode for GABA at these receptors

    Karim, N., Wellendorph, Petrine, Absalom, N., Bang, L. H., Jensen, M. L., Hansen, M. M., Lee, H. J., Johnston, G. A. R., Hanrahan, J. R. & Chebib, M., 15 Aug 2012, In: Biochemical Pharmacology. 84, 4, p. 549-557

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2011
  30. Published

    3-Hydroxy-2'-methoxy-6-methylflavone: a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes

    Karim, N., Gavande, N., Wellendorph, Petrine, Johnston, G. A. R., Hanrahan, J. R. & Chebib, M., 15 Dec 2011, In: Biochemical Pharmacology. 82, 12, p. 1971-1983

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner, Hans, 23 Nov 2011, In: Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Kemogenomik: Receptoren set fra lægemiddelstoffets synspunkt

    Johansson, H., Jørgensen, T. B., Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Pedersen, D. S. & Bräuner, Hans, 2011, In: Dansk Kemi. 92, 11, p. 22-26

    Research output: Contribution to journal › Journal article › Research

Previous 1 2 3 4 Next

ID: 1301791