Povl Krogsgaard-Larsen
Professor, emeritus
Medicinal Chemistry
Jagtvej 162
2100 København Ø
GABAA agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of Hypnotic
Krogsgaard-Larsen, Povl, Frølund, B., Liljefors, T. & Ebert, B., 2004, In: Biochemical Pharmacology. 68, p. 1573–1580Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel (Gamma-Aminobutyric Acid)A Agonists and Partial Agonists
Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe, Lambert, J. D. C., Falch, E. & Curtis, D. R., 1991, Transmitter Amino Acid Receptors. Barnard, E. A. & Costa, E. (eds.). Raven Press, p. 237–249Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Synergies within the natural sciences at the University of Copenhagen: an interfaculty evaluation of barriers and opportunities to improve the quality of infrastructure, research and education
Krogsgaard-Larsen, Povl, Møller, Birger Lindberg, Larsen, Erik Hviid, Vestergaard, Bente, Lunde, C., Stæhr, P. A. & Andersen, J. (ed.), 2009, Faculty of Life Sciences: Museum Tusculanum. 43 p.Research output: Book/Report › Book › Research
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GABAA agonists and partial agonists
Krogsgaard-Larsen, Povl, Frølund, Bente & Liljefors, T., 2002, In: The Chemical Record. 2, p. 419–430Research output: Contribution to journal › Journal article › Research › peer-review
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Structural, stereochemical and conformational requirements for activation and blockade of central glutamic acid receptors
Krogsgaard-Larsen, Povl, Madsen, Ulf, Brehm, L., Christensen, I. T., Nielsen, Birgitte, Reinhardt, A., Ebert, B. & Hansen, J. J., 1990, Problems and Wonders of Chirale Molecules. Simonyi, M. (ed.). Budapest: Akadémiai Kiadó, p. 205-225 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Textbook of drug design and discovery
Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.Research output: Book/Report › Book › Education
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GABA(A) and GABA(B) receptor agonists, partial agonists, antagonists and modulators: Design and therapeutic prospects
Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe, Frydenvang, Karla Andrea & Ebert, B., Nov 1997, In: European Journal of Pharmaceutical Sciences. 5, 6, p. 355-384 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific GABAA agonists and partial agonists
Krogsgaard-Larsen, Povl, Frølund, Bente & Liljefors, T., 1 Nov 2002, In: Chemical Record. 2, 6, p. 419-430 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GABAA Agonists and Partial Agonists: THIP (Gaboxadol) as a Non-Opioid Analgesic and a Novel Type of Hypnotic
Krogsgaard-Larsen, Povl, Frølund, Bente, Liljefors, T. & Ebert, B., 2006, GABA. Enna, S. (ed.). p. 53–71 (Advances in Pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Ligands for the GABAA receptor complex
Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe & Ebert, B., 2002, Glutamate and GABA receptors of AMPA/kainate receptors and transporters. Taylor & Francis, p. 236–274Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Introduction to drug design and discovery
Krogsgaard-Larsen, Povl & Bunch, Lennart, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 1-13Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Medicinal chemical and pharmacological focus on GABA and glutamic acid receptors in neurodegenerative disorders
Krogsgaard-Larsen, Povl, Hedegaard, A., Nielsen, L., Nielsen, Birgitte, Madsen, Ulf, Brehm, L., Falch, E., Hjeds, H. & Hansen, J. J., 1989, Trends in Medicinal Chemistry '88. van der Goot, H., Domány, G., Pallos, L. & Timmerman, H. (eds.). Elsevier, Amsterdam, p. 429-452 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Molecular pharmacology of excitatory amino acid receptors: conformational and stereochemical requirements
Krogsgaard-Larsen, Povl, Madsen, Ulf, Nielsen, Birgitte, Hansen, J. J., Nielsen, E. Ø., Brehm, L. & Curtis, D. R., 1987, Proceedings of the X'th International Congress of Pharmacology. Rand, M. J. & Raper, C. (eds.). Elsevier, p. 113-116 4 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Scientific social responsibility: a call to arms
Krogsgaard-Larsen, Povl, Thostrup, P. & Besenbacher, F., 11 Nov 2011, In: Angewandte Chemie International Edition. 50, 46, p. 10738-10740Research output: Contribution to journal › Comment/debate › Research
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GABA A agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic
Krogsgaard-Larsen, Povl, Frølund, Bente, Liljefors, T. & Ebert, B., 15 Oct 2004, In: Biochemical Pharmacology. 68, 8, p. 1573-1580 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibitors of γ-aminobutyric acid transport as experimental tools and therapeutic agents
Krogsgaard-Larsen, Povl, Frølund, Bente & Falch, E., 1998, Methods in enzymology. p. 165–175 (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Excitatory amino acid research in Alzheimer´s disease: activation, enhancement and blockade of receptor subtypes
Krogsgaard-Larsen, Povl, Nielsen, Birgitte & Hansen, J. J., 1993, Advances in Neuropharmacology. Ross, F. C. (ed.). London: Smith-Gordon and Company Limited, p. 241-248 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Ligands for the GABAA receptor complex
Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe & Ebert, B., 1 Jan 2001, Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology. CRC Press, p. 236-274 39 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Selective antagonists at group I metabotropic glutamate receptors: synthesis and molecular pharmacology of 4-aryl-3-isoxazolol amino acids
Kromann, H., Sløk, F. A., Stensbøl, T. B., Bräuner, Hans, Madsen, Ulf & Krogsgaard-Larsen, Povl, 14 Feb 2002, In: Journal of Medicinal Chemistry. 45, 4, p. 988-91Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors
Kromann, H., Krikstolaityte, S., Andersen, A. J., Andersen, K., Krogsgaard-Larsen, Povl, Jaroszewski, J. W., Egebjerg, J. & Strømgaard, Kristian, 19 Dec 2002, In: Journal of Medicinal Chemistry. 45, 26, p. 5745-5754 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AMPA receptor agonists, design, synthesis and molecular pharmacology
Lund, Trine Meldgaard, Christensen, I. T., Madsen, Ulf, Ebert, B., Brehm, L. & Krogsgaard-Larsen, Povl, 1990, In: Neurochemistry International. 16 suppl 1, 51, p. 51 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Conformational and pharmacological characterization of 4-AHCP, a bicyclic homologue of the excitatory amino acid receptor agonist AMPA
Lund, Trine Meldgaard, Madsen, Ulf, Ebert, B., Jørgensen, Flemming Steen & Krogsgaard-Larsen, Povl, 1991, In: Med. Chem. Res. 1, p. 136-141 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acidC receptor agonists
Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4147-4161Research output: Contribution to journal › Journal article › Research › peer-review
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5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists
Madsen, C., Jensen, Anders A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, p. 4147-4161Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional and pharmacological aspects of GABA transporters
Madsen, K., White, H. S., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O. M., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2007, Handbook of nerochemistry and molecular neurobiology: Neural membranes and transport. Lajtha, A. & Reith, M. E. A. (eds.). 3rd. ed. Berlin: Springer, Vol. 3. p. 285-304Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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