Stephan Pless

Stephan Pless

Professor

ORCID: 0000-0001-6654-114X

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  1. Published

    Stoichiometry of Toxin Binding to Acid-Sensing Ion Channels

    Borg, C. B., Lynagh, T., Haugaard-Kedstrom, L. M., Strømgaard, Kristian & Pless, Stephan, 3 Feb 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 420A-420A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  2. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Peptide Modulation of Acid-Sensing Ion Channels

    Borg, C. B., Haugaard-Kedstrom, L. M., Lynagh, T., Strømgaard, Kristian & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conference › Poster › Research

  5. Published

    The current chemical biology tool box for studying ion channels

    Braun, N., Sheikh, Zeshan Pervez & Pless, Stephan, 2020, In: The Journal of Physiology. 598, 20, p. 4455-4471 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology

    Braun, N., Friis, S., Ihling, C., Sinz, A., Andersen, J. & Pless, Stephan, 2021, In: PLOS Biology. 19, 9, 30 p., e3001321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Role of an Absolutely Conserved Tryptophan Pair in the Extracellular Domain of Cys-Loop Receptors

    Braun, N., Lynagh, T., Yu, R., Biggin, P. C. & Pless, Stephan, 29 Jan 2016, In: A C S Chemical Neuroscience. 7, 3, p. 339–348 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Investigation of Agonist Recognition and Channel Properties in a Flatworm Glutamate-Gated Chloride Channel

    Callau-Vázquez, D., Pless, Stephan & Lynagh, T., 2018, In: Biochemistry. 57, 8, p. 1360-1368

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium

    Chua, H. C., Wulf, M., wbv551, wbv551, Rasmussen, L. P. & Pless, Stephan, Apr 2020, In: Science Advances. 6, 17, 11 p., aaz3154.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Unexplained cardiac arrest: a tale of conflicting interpretations of KCNQ1 genetic test results

    Chua, H. C., Servatius, H., Asatryan, B., Schaller, A., Rieubland, C., Noti, F., Seiler, J., Roten, L., Baldinger, S. H., Tanner, H., Fuhrer, J., Haeberlin, A., Lam, A., Pless, Stephan & Medeiros-Domingo, A., 1 Aug 2018, In: Clinical Research in Cardiology. 107, 8, p. 670-678 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The Sodium Leak Channel Complex is Modulated by Voltage and Extracellular Calcium

    Chua, H. C., Wulf, M., wbv551, wbv551, Rasmussen, L. P. & Pless, Stephan, 7 Feb 2020, p. 499A-499A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  12. Published

    Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

    Galleano, I., Harms, Hendrik, Choudhury, K., Khoo, K., Delemotte, L. & Pless, Stephan, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 33, 10 p., e2025320118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Interplay of Nav1.5 Disease-Causing Mutations and Phosphorylation Revealed by Protein Semi-Synthesis and Molecular Dynamics Simulations

    Galleano, I., Harms, Hendrik, Choudhury, K., Khoo, K. K., Delemotte, L. & Pless, Stephan, 2021, p. 288A-288A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  14. Published

    P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity

    Gasparri, F., Sarkar, Debayan, Bielickaite, S., Poulsen, Mette Homann, Hauser, Alexander Sebastian & Pless, Stephan, 2022, In: British Journal of Pharmacology. 179, 14, p. 3859-3874

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Molecular determinants for agonist recognition and discrimination in P2X2 receptors

    Gasparri, F., Wengel, J., Grutter, T. & Pless, Stephan, 24 May 2019, In: Journal of General Physiology. 151, 7, p. 898–911

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effects of Ligand Conformations and Hetero-Liganded States on P2X2 Receptors

    Gasparri, F., Wengel, J., Grutter, T. & Pless, Stephan, 3 Feb 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 421A-421A 2069-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    Unravelling the functional regulation of the NALCN sodium leak channel complex by G protein-coupled receptors

    Harms, Hendrik & Pless, Stephan, 2023, In: Biophysical Journal. 122, 3 Suppl. 1, p. 163a

    Research output: Contribution to journal › Conference abstract in journal › Research

  18. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation

    Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, I. & Pless, Stephan, 2021, p. 337A-337A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  20. Published

    Acid-sensing ion channels as potential therapeutic targets

    Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050

    Research output: Contribution to journal › Review › Research › peer-review

  21. E-pub ahead of print

    Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions

    Holm, Caroline Marcher, Topaktas, Asli Bahar, Dannesboe, Johs, Pless, Stephan & Heusser, Stephanie, 2024, (E-pub ahead of print) In: Biophysical Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons

    Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Vitello, M., Chua, H. C., Pless, Stephan, Engel, D., Liégeois, J. F., Lakaye, B., Roeper, J. & Seutin, V., 2021, In: Neuropharmacology. 197, 15 p., 108722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels

    Kasimova, M. A., Lynagh, T., Sheikh, Zeshan Pervez, Granata, D., Borg, C. B., Carnevale, V. & Pless, Stephan, 2020, In: Biophysical Journal. 118, 4, p. 861-872 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

    Khoo, K. K., Galleano, I., Gasparri, F., Wieneke, R., Harms, Hendrik, Poulsen, Mette Homann, Chua, H. C., Wulf, M., Tampé, R. & Pless, Stephan, 1 Dec 2020, In: Nature Communications. 11, 1, 10 p., 2284.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    How an intrinsic ligand tunes the activity of a potassium channel

    Khoo, K. K. & Pless, Stephan, 22 Mar 2018, In: Journal of General Physiology. 150, 4, p. 517-520

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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ID: 93715174