Stephan Pless

Stephan Pless

Professor

ORCID: 0000-0001-6654-114X

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  1. Published

    A New Method to Detect Intra- and Extracellular Conformational Changes in Ion Channels with High Temporal Resolution

    Wulf, M. & Pless, Stephan, 3 Feb 2017, In: Biophysical Journal. 12, 3, p. 285A-285A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  2. Published

    A Semi-Synthetic Approach to Engineer Ligand- and Voltage-Gated Ion Channels in Live Cells

    Khoo, K. K., Galleano, I. & Pless, Stephan, 2019, p. 274A-274A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  3. Published

    A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue

    Pless, Stephan, Millen, K. S., Hanek, A. P., Lynch, J. W., Lester, H. A., Lummis, S. C. R. & Dougherty, D. A., 22 Oct 2008, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 28, 43, p. 10937-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists

    Pless, Stephan, Hanek, A. P., Price, K. L., Lynch, J. W., Lester, H. A., Dougherty, D. A. & Lummis, S. C. R., Apr 2011, In: Molecular Pharmacology. 79, 4, p. 742-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A conserved residue cluster that governs kinetics of ATP-dependent gating of Kir6.2 potassium channels

    Zhang, R. S., Wright, J., Pless, Stephan, Nunez, J., Kim, R. Y., Li, J. B. W., Yang, R., Ahern, C. A. & Kurata, H. T., 2015, In: The Journal of Biological Chemistry. 290, 25, p. 15450 –15461 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

    Pless, Stephan, Niciforovic, A. P., Galpin, J. D., Nunez, J., Kurata, H. T. & Ahern, C. A., 2013, In: Nature Communications. 4, p. 1784

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A selectivity filter at the intracellular end of the acid-sensing ion channel pore

    Lynagh, T., Flood, E., Boiteux, C., Wulf, M., Komnatnyy, V. V., Colding, J. M., Allen, T. W. & Pless, Stephan, 12 May 2017, In: eLife. 6, 21 p., 24630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A tale of ligands big and small: An update on how pentameric ligand-gated ion channels interact with agonists and proteins

    Pless, Stephan & Sivilotti, L. G., 1 Apr 2018, In: Current Opinion in Physiology. 2, p. 19-26 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    ATP signaling in pancreatic cancer: the P2X7 receptor

    Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Acid-sensing ion channels as potential therapeutic targets

    Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes

    Lynagh, T., Mikhaleva, Y., Colding, J. M., Glover, J. C. & Pless, Stephan, 14 Aug 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 33, p. 8430-8435

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

    Pless, Stephan, Elstone, F. D., Niciforovic, A. P., Galpin, J. D., Yang, R., Kurata, H. T. & Ahern, C. A., May 2014, In: Journal of General Physiology. 143, 5, p. 645-56 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology

    Pless, Stephan, Kim, R. Y., Ahern, C. A. & Kurata, H. T., 30 Jan 2015, In: The Journal of Physiology. 593, 12, p. 2627–2634 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Atomic basis for therapeutic activation of neuronal potassium channels

    Kim, R. Y., Yau, M. C., Galpin, J. D., Seebohm, G., Ahern, C. A., Pless, Stephan & Kurata, H. T., 2015, In: Nature Communications. 6, p. 1-11 11 p., 8116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Caught in the act: multiple binding sites for memantine

    Pless, Stephan, 2014, In: Structure. 22, 10, p. 1373-4 2 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  16. Published

    Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation

    Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, I. & Pless, Stephan, 2021, p. 337A-337A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

    Khoo, K. K., Galleano, I., Gasparri, F., Wieneke, R., Harms, Hendrik, Poulsen, Mette Homann, Chua, H. C., Wulf, M., Tampé, R. & Pless, Stephan, 1 Dec 2020, In: Nature Communications. 11, 1, 10 p., 2284.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Conformational variability of the glycine receptor M2 domain in response to activation by different agonists

    Pless, Stephan, Dibas, M. I., Lester, H. A. & Lynch, J. W., 7 Dec 2007, In: The Journal of Biological Chemistry. 282, 49, p. 36057-67 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Contributions of conserved residues at the gating interface of glycine receptors

    Pless, Stephan, Leung, A. W. Y., Galpin, J. D. & Ahern, C. A., 7 Oct 2011, In: The Journal of Biological Chemistry. 286, 40, p. 35129-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Contributions of counter-charge in a potassium channel voltage-sensor domain

    Pless, Stephan, Galpin, J. D., Niciforovic, A. P. & Ahern, C. A., Sep 2011, In: Nature Chemical Biology. 7, 9, p. 617-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

    Lynagh, T., Flood, E., Boiteux, C., Sheikh, Zeshan Pervez, Allen, T. W. & Pless, Stephan, 3 Feb 2020, In: The Journal of general physiology. 152, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Distinct conformational changes in activated agonist-bound and agonist-free glycine receptor subunits

    Pless, Stephan & Lynch, J. W., Mar 2009, In: Journal of Neurochemistry. 108, 6, p. 1585-94 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. E-pub ahead of print

    Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions

    Holm, Caroline Marcher, Topaktas, Asli Bahar, Dannesboe, Johs, Pless, Stephan & Heusser, Stephanie, 2024, (E-pub ahead of print) In: Biophysical Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Effects of Ligand Conformations and Hetero-Liganded States on P2X2 Receptors

    Gasparri, F., Wengel, J., Grutter, T. & Pless, Stephan, 3 Feb 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 421A-421A 2069-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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