Stephanie Heusser
Assistant Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
Acid-sensing ion channels as potential therapeutic targets
Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050Research output: Contribution to journal › Review › Research › peer-review
- E-pub ahead of print
Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions
Holm, Caroline Marcher, Topaktas, Asli Bahar, Dannesboe, Johs, Pless, Stephan & Heusser, Stephanie, 2024, (E-pub ahead of print) In: Biophysical Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing Allosteric Networks in Ligand-Gated Ion Channel Gating by Electrophysiology and Molecular Dynamics in the Model Receptor GLIC
Howard, R. J., Zhuang, Y., Gutheim, S., Zeckey, L., Heusser, Stephanie & Lindahl, E. R., 2021, p. 58A-58A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Allosteric Gating Determinants in the Transmembrane Domain of Pentameric Ligand-Gated Ion Channels
Howard, R. J., Zhuang, Y., Heusser, Stephanie, Bergh, C. C., Rovsnik, U., Orellana, L. & Lindahl, E., 2020, p. 584A-584A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel
Noland, C. L., Chua, H. C., Kschonsak, M., Heusser, Stephanie, Braun, N., Chang, T., Tam, C., Tang, J., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature Communications. 13, 1, 10 p., 1416.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels
Sarkar, Debayan, Galleano, I., Heusser, Stephanie, Ou, S. Y., Uzun, G. R., Khoo, K. K., van der Heden van Noort, G. J., Harrison, J. S. & Pless, Stephan, 2024, (Accepted/In press) In: Cell Chemical Biology.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 203075805
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21
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Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels
Research output: Contribution to journal › Journal article › Research › peer-review
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14
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Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
11
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Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published