Trond Ulven

Trond Ulven

Professor

Member of:


    1. 2020
    2. Published

      FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells

      Lorza-Gil, E., Kaiser, G., Ulven, Elisabeth Rexen, Koenig, G. M., Gerst, F., Oquendo, M. B., Birkenfeld, A. L., Haering, H., Kostenis, E., Ulven, Trond & Ullrich, S., 2020, In: Scientific Reports. 10, 1, 11 p., 16497.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice

      Murtaza, B., Hichami, A., Khan, A. S., Shimpukade, B., Ulven, Trond, Ozdener, M. H. & Khan, N. A., 2020, In: Journal of Lipid Research. 61, 2, p. 133-142 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Pathophysiological regulation of lung function by the free fatty acid receptor FFA4

      Prihandoko, R., Kaur, D., Wiegman, C. H., Alvarez-Curto, E., Donovan, C., Chachi, L., Ulven, Trond, Tyas, M. R., Euston, E., Dong, Z., Alharbi, A. G. M., Kim, R. Y., Lowe, J. G., Hansbro, P. M., Chung, K. F., Brightling, C. E., Milligan, G. & Tobin, A. B., 2020, In: Science Translational Medicine. 12, 557, 13 p., 9009.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

      Sencio, V., Barthelemy, A., Tavares, L. P., Machado, M. G., Soulard, D., Cuinat, C., Queiroz-Junior, C. M., Noordine, M. L., Salomé-Desnoulez, S., Deryuter, L., Foligné, B., Wahl, C., Frisch, B., Vieira, A. T., Paget, C., Milligan, G., Ulven, T., Wolowczuk, I., Faveeuw, C., Le Goffic, R. & 4 others, Thomas, M., Ferreira, S., Teixeira, M. M. & Trottein, F., 3 Mar 2020, In: Cell Reports. 30, 9, p. 2934-2947.e6

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

      Ulven, Elisabeth Rexen, Quon, T., Sergeev, E., Barki, N., Brvar, M., Hudson, B. D., Dutta, P., Hansen, A. H., Bielefeldt, L. Ø., Tobin, A. B., McKenzie, C. J., Milligan, G. & Ulven, Trond, 9 Apr 2020, In: Journal of Medicinal Chemistry. 63, 7, p. 3577-3595 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2019
    8. Published

      Preparation of substituted pyrrolo[2,3-c]pyridine-2-carboxamides and thieno[2,3-c]pyridine-2-carboxamides as AMPK inhibitors.

      Lanz, J. & Ulven, Trond, 6 Jun 2019, WIPO. World Intellectual Property Organisation, Patent No. WO2019106087A1

      Research output: Patent

    9. Published

      Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1

      Larsen, Olav, Lückmann, Michael, van der Velden, W. J. C., Oliva-Santiago, M., Brvar, M., Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 2019, In: ACS Pharmacology & Translational Science. 2, 6, p. 429-441 13 p.

      Research output: Contribution to journalLetterResearchpeer-review

    10. Published

      Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival

      Theiler, A., Bärnthaler, T., Platzer, W., Richtig, G., Peinhaupt, M., Rittchen, S., Kargl, J., Ulven, Trond, Marsh, L. M., Marsche, G., Schuligoi, R., Sturm, E. M. & Heinemann, A., 2019, In: The Journal of allergy and clinical immunology. 144, 3, p. 764-776

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 2018
    12. Published

      Preparation of tetrahydroisoquinoline and tetrahydrobenzoazepine derivatives for use as GPR120 modulators.

      Brown, J., Connolly, S., Hansen, S. V. F., Milne, G., Shimpukade, B., Smyth, D., Thomas, G., Ulven, Trond, Brvar, M. & Rigby, A., 27 Sep 2018, Caldan Therapeutics Limited, UK ., Patent No. WO2018172727A1

      Research output: Patent

    13. Published

      Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum

      Domljanovic, I., Ulven, Elisabeth Rexen, Ulven, Trond, Thomsen, R. P., Okholm, A. H., Kjems, J., Voss, A., Taskova, M. & Astakhova, K., 31 Jul 2018, In: ACS Omega. 3, 7, p. 7580-7586 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties

      Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

      Schilperoort, M., van Dam, A. D., Hoeke, G., Shabalina, I. G., Okolo, A., Hanyaloglu, A. C., Dib, L. H., Mol, I. M., Caengprasath, N., Chan, Y., Damak, S., Miller, A. R., Coskun, T., Shimpukade, B., Ulven, Trond, Kooijman, S., Rensen, P. C. & Christian, M., 17 Jan 2018, In: E M B O Molecular Medicine. 10, 3, 18 p., e8047.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2017
    17. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

      Dragano, N. R. V., Solon, C., Ramalho, A. F., de Moura, R. F., Razolli, D. S., Ulven, Elisabeth Rexen, Goncalves de Azavedo, C. M. B. P., Ulven, Trond & Velloso, L. A., 2017, In: Journal of Neuroinflammation. 14, 91, 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Development and Characterization of a Fluorescent Tracer for the Free Fatty Acid Receptor 2 (FFA2/GPR43)

      Hansen, A. H., Sergeev, E., Pandey, S. K., Hudson, B. D., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2017, In: Journal of Medicinal Chemistry. 60, 13, p. 5638-5645 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120)

      Hansen, S. V. F. & Ulven, Trond, 2017, Free Fatty Acid Receptors. Springer Science+Business Media, p. 33-56 24 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    20. Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance

      Houthuijzen, J. M., Oosterom, I., Hudson, B. D., Hirasawa, A., Daenen, L. G. M., McLean, C. M., Hansen, S. V. F., van Jaarsveld, M. T. M., Peeper, D. S., Jafari Sadatmand, S., Roodhart, J. M. L., van de Lest, C. H. A., Ulven, Trond, Ishihara, K., Milligan, G. & Voest, E., 2017, In: F A S E B Journal. 31, 5, p. 2195-2209 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Succinct synthesis of saturated hydroxy fatty acids and

      Kaspersen, M. H., Jenkins, L., Dunlop, J., Milligan, G. & Ulven, Trond, 2017, In: MedChemComm. 8, 6, p. 1360-1365 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84

      Mahmud, Z. A., Jenkins, L., Ulven, Trond, Labéguère, F., Gosmini, R., De Vos, S., Hudson, B. D., Tikhonova, I. G. & Milligan, G., 2017, In: Scientific Reports. 7, 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Complex Pharmacology of Free Fatty Acid Receptors

      Milligan, G., Shimpukade, B., Ulven, Trond & Hudson, B. D., 11 Jan 2017, In: Chemical Reviews. 117, 1, p. 67-110 44 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias

      Sergeev, E., Hansen, A. H., Bolognini, D., Kawakami, K., Kishi, T., Aoki, J., Ulven, Trond, Inoue, A., Hudson, B. D. & Milligan, G., 2017, In: Scientific Reports. 7, 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4

      Watterson, K. R., Hansen, S. V. F., Hudson, B. D., Alvarez-Curto, E., Raihan, S. Z., Goncalves de Azavedo, C. M. B. P., Martin, G., Dunlop, J., Yarwood, S. J., Ulven, Trond & Milligan, G., 2017, In: Molecular Pharmacology. 91, 6, p. 630-641 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2016
    27. The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment

      Björkman, L., Mårtensson, J., Winther, M., Gabl, M., Holdfeldt, A., Uhrbom, M., Bylund, J., Højgaard Hansen, A., Pandey, S. K., Ulven, Trond, Forsman, H. & Dahlgren, C., 2016, In: Molecular and Cellular Biology. 36, 20, p. 2583-2595 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer

      Ulven, Elisabeth Rexen, Hudson, B. D., Hansen, A. H., Milligan, G. & Ulven, Trond, 2016, In: Journal of Medicinal Chemistry. 59, 10, p. 4849-4858 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

      Due-Hansen, M. E., Pandey, S. K., Ulven, Elisabeth Rexen, Andersen, R., Hansen, S. V. F. & Ulven, Trond, 2016, In: Organic & Biomolecular Chemistry. 14, 2, p. 430-433 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity

      Goncalves de Azavedo, C. M. B. P., Watterson, K. R., Wargent, E. T., Hansen, S. V. F., Hudson, B. D., Kępczyńska, M. A., Dunlop, J., Shimpukade, B., Ulven, Elisabeth Rexen, Milligan, G., Stocker, C. J. & Ulven, Trond, 2016, In: Journal of Medicinal Chemistry. 59, 19, p. 8868-8878 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 187375453