Trond Ulven
Professor
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area and Robust in Vivo Efficacy
Hansen, S. V. F., Ulven, Elisabeth Rexen, Urban, C., Hudson, B. D., Stocker, C. J., Due-Hansen, M. E., Wargent, E. T., Shimpukade, B., Almeida, R., Ejsing, C. S., Cawthorne, M. A., Kassack, M. U., Milligan, G. & Ulven, Trond, 1 Mar 2016, In: Journal of Medicinal Chemistry. 59, 6, p. 2841-2846 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a potent and selective GPR120 agonist
Shimpukade, B., Hudson, B. D., Hovgaard, C. K., Milligan, G. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 9, p. 4511-4515 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Discovery of a potent and selective free fatty acid receptor 1 agonist with low lipophilicity and high oral bioavailability
Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schmidt, J., Hansen, S. V. F., Hudson, B. D., Zaibi, M., Markussen, S. B., Hagesaether, E., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 982-992 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes
Ulven, Elisabeth Rexen, Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., Spinrath, A., Bond, A. D., Drewke, C., Ullrich, S., Kassack, M. U., Kostenis, E. & Ulven, Trond, 27 Nov 2008, In: Journal of Medicinal Chemistry. 51, 22, p. 7061-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein-Coupled Receptor 120
Prihandoko, R., Alvarez-Curto, E., Hudson, B. D., Butcher, A. J., Ulven, Trond, Miller, A. M., Tobin, A. B. & Milligan, G., 2016, In: Molecular Pharmacology. 89, 5, p. 505-520 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug Repurposing in Crohn's Disease Using Danish Real-World Data
Shakibfar, Saeed, Allin, K. H., Jess, T., Barbieri, M. A., Battini, V., Simoncic, E., Kirchgesner, J., Ulven, Trond & Sessa, Maurizio, 2024, In: Pragmatic and observational research. 15, p. 17-29Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of delayed-release olive oil and hydrolyzed pine nut oil on glucose tolerance, incretin secretion and appetite in humans
Sørensen, K. V., Kaspersen, M. H., Ekberg, J. H., Bauer-Brandl, A., Ulven, Trond & Højlund, K., 2021, In: Nutrients. 13, 10, 13 p., 3407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides
Larsen, A. F. & Ulven, Trond, 2011, In: Organic Letters. 13, 13, p. 3546-3548 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging roles of DP and CRTH2 in allergic inflammation
Kostenis, E. & Ulven, Trond, 2006, In: Trends in Molecular Medicine. 12, 4, p. 148-158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ethyl 2-(1,2,3,4-tetrahydrospiro[carbazole-3,2'- [1,3]dioxolan]-9-yl)acetate
Loffler, P., Ulven, Trond & Bond, A., 2009, In: Acta Crystallographica. Section E: Structure Reports Online. 65, Section E, p. o685Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3
Hudson, B. D., Tikhonova, I. G., Pandey, S. K., Ulven, Trond & Milligan, G., 2012, In: Journal of Biological Chemistry. 287, 49, p. 41195-41209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular loop 2 of the free Fatty Acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator
Smith, N. J., Ward, R. J., Stoddart, L. A., Hudson, B. D., Kostenis, E., Ulven, Trond, Morris, J. C., Tränkle, C., Tikhonova, I. G., Adams, D. R. & Milligan, G., 2011, In: Molecular Pharmacology. 80, 1, p. 163-173 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extraction of G-quadruplex ligands from disulfide-based dynamic combinatorial libraries
Nielsen, Mads & Ulven, Trond, 2009, p. ORGN-345.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
FFA1/Gq - Gi interaction determines glucose-induced insulin secretion of neonatal beta cells
Gerst, F., Lorza-Gil, E., Kaiser, G., Ulven, Trond, Kostenis, E., Haring, H. -., Birkenfeld, A. L. & Ullrich, S., 2022, In: Diabetologia. 65, Suppl 1, p. S109-S109Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells
Lorza-Gil, E., Kaiser, G., Ulven, Elisabeth Rexen, Koenig, G. M., Gerst, F., Oquendo, M. B., Birkenfeld, A. L., Haering, H., Kostenis, E., Ulven, Trond & Ullrich, S., 2020, In: Scientific Reports. 10, 1, 11 p., 16497.Research output: Contribution to journal › Journal article › Research › peer-review
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Houthuijzen, J. M., Oosterom, I., Hudson, B. D., Hirasawa, A., Daenen, L. G. M., McLean, C. M., Hansen, S. V. F., van Jaarsveld, M. T. M., Peeper, D. S., Jafari Sadatmand, S., Roodhart, J. M. L., van de Lest, C. H. A., Ulven, Trond, Ishihara, K., Milligan, G. & Voest, E., 2017, In: F A S E B Journal. 31, 5, p. 2195-2209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow chemistry methods for the synthesis chemokine receptor ligands
Petersen, T. P., Ritzén, A. & Ulven, Trond, 2009, p. ORGN-570.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists
Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schröder, R., Hudson, B. D., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 14, p. 6624-6628 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional-Group-Tolerant Pd-Catalyzed Carbonylative Negishi Coupling with Aryl Iodides
Kalinin, D. V. & Ulven, Trond, 2023, In: Journal of Organic Chemistry. 88, 23, p. 16633-16638Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G protein-coupled receptor modulators and a pharmaceutical composition
Ulven, Trond & Ieremias, L., 2021, IPC No. A61K31/44, A61P25/00, A61P29/00, C07D213/69, C07D405/12, Patent No. WO 2021/123394 A1, 18 Dec 2020, Priority date 20 Dec 2019, Priority No. EP20150090AResearch output: Patent
G-protein-coupled receptors for free fatty acids
Milligan, G., Ulven, Trond, Murdoch, H. & Hudson, B. D., 2 Jan 2014, In: British Journal of Nutrition. 111, Supplement S1, p. S3-S7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR120 receptor modulators
Ulven, Trond & Shimpukade, B., 26 Sep 2013, Patent No. WO 2013/139341 A1Research output: Patent
- Published
GPR120 receptor modulators
Ulven, Trond & Shimpukade, B., 19 Dec 2013, Patent No. WO 2013/185766 A1Research output: Patent
- Published
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets
Lorza-Gil, E., Kaiser, G., Carlein, C., Hoffmann, M. D. A., König, G. M., Haug, S., Prates Roma, L., Ulven, Elisabeth Rexen, Ulven, Trond, Kostenis, E., Birkenfeld, A. L., Häring, H. U., Ullrich, S. & Gerst, F., 2023, In: Diabetologia. 66, p. 1501–1515Research output: Contribution to journal › Journal article › Research › peer-review
ID: 187375453
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Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Research output: Contribution to journal › Journal article › Research › peer-review
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Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
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Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum
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