Trond Ulven

Trond Ulven

Professor

Member of:


    1. 2011
    2. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

      Schmidt, J., Smith, N. J., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Hudson, B. D., Ward, R. J., Drewke, C., Milligan, G., Kostenis, E. & Ulven, Trond, 10 Jan 2011, In: Journal of Biological Chemistry. 286, 12, p. 10628-10640 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Method of synthesizing a 5-oxo-conjugated fatty acid

      Ulven, Trond & Tyagi, R., 27 Oct 2011, Patent No. WO 2011/131619 A1

      Research output: Patent

    4. 2012
    5. Published

      A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer

      Blättermann, S., Peters, L., Ottersbach, P. A., Bock, A., Konya, V., Weaver, C. D., Gonzalez, A., Schröder, R., Tyagi, R., Luschnig, P., Gäb, J., Hennen, S., Ulven, Trond, Pardo, L., Mohr, K., Gütschow, M., Heinemann, A. & Kostenis, E., 2012, In: Nature Chemical Biology. 8, 7, p. 631-638 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

      Tyagi, R., Shimpukade, B., Blättermann, S., Kostenis, E. & Ulven, Trond, 2012, In: MedChemComm. 3, p. 195-198 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

      Hudson, B. D., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Kostenis, E., Adams, D. R., Ulven, Trond & Milligan, G., 2012, In: F A S E B Journal. 26, 12, p. 4951-4965 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Discovery of a potent and selective GPR120 agonist

      Shimpukade, B., Hudson, B. D., Hovgaard, C. K., Milligan, G. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 9, p. 4511-4515 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3

      Hudson, B. D., Tikhonova, I. G., Pandey, S. K., Ulven, Trond & Milligan, G., 2012, In: Journal of Biological Chemistry. 287, 49, p. 41195-41209 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

      Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schröder, R., Hudson, B. D., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 14, p. 6624-6628 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2

      Schröder, R., Xue, L., Konya, V., Martini, L., Kampitsch, N., Whistler, J. L., Ulven, Trond, Heinemann, A., Pettipher, R. & Kostenis, E., 2012, In: P L o S One. 7, 3, p. e33329

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

      Ulven, Trond, 2012, In: Frontiers in Endocrinology. 3

      Research output: Contribution to journalJournal articleResearchpeer-review

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