Trond Ulven

Trond Ulven

Professor

Member of:

    ORCID: 0000-0002-8135-1755

    Publication year:
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    101 - 125 out of 157Page size: 25
    1. 2011

    2. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties

      Ulven, Elisabeth Rexen, Urban, C., Grundmann, M., Due-Hansen, M. E., Hagesaether, E., Schmidt, J., Pardo, L., Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2011, In: Journal of Medicinal Chemistry. 54, 19, p. 6691-6703 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2010
    4. Published

      Novel CRTH2 antagonists: a review of patents from 2006 to 2009

      Ulven, Trond & Kostenis, E., 1 Nov 2010, In: Expert Opinion on Therapeutic Patents. 20, 11, p. 1505-1530 26 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. A Rapid and Efficient Sonogashira Protocol and Improved Synthesis of Free Fatty Acid 1 (FFA1) Receptor Agonists

      Ulven, Elisabeth Rexen, Due-Hansen, M. E. & Ulven, Trond, 19 Feb 2010, In: Journal of Organic Chemistry. 75, 4, p. 1301-1304 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Compounds for the treatment of metabolic diseases

      Ulven, Trond & Christiansen, E., 4 Feb 2010, Patent No. WO 2010/012650

      Research output: Patent

    7. Published

      Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2

      Grimstrup, M., Rist, Ø., Receveur, J., Frimurer, Thomas Michael, Ulven, Trond, Mathiesen, Jesper M., Kostenis, E. & Högberg, T., 1 Feb 2010, In: Bioorganic & Medicinal Chemistry Letters. 20, 3, p. 1181-1185 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Macrocyclic G-quadruplex ligands

      Nielsen, M. C. & Ulven, Trond, 1 Jan 2010, In: Current Medicinal Chemistry. 17, 29, p. 3438-3448 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

      Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, Karsten, Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2010, In: ACS Medicinal Chemistry Letters. 1, 7, p. 345-349 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    10. Published

      Targeting the prostaglandin D2 receptors DP1 and CRTH2 for treatment of inflammation

      Ulven, Trond & Kostenis, E., 2010, Frontiers in Medicinal Chemistry. Bentham Science Publishers, Vol. 5.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    11. 2009
    12. Published

      Design, synthesis and evaluation of 4,7-diamino-1,10-phenanthroline G-quadruplex ligands

      Nielsen, M. C., Borch, J. & Ulven, Trond, 15 Dec 2009, In: Bioorganic & Medicinal Chemistry. 17, 24, p. 8241-8246 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1

      Rist, O., Grimstrup, M., Receveur, J., Frimurer, Thomas Michael, Ulven, Trond, Kostenis, E. & Högberg, T., 4 Dec 2009, In: Bioorganic & Medicinal Chemistry Letters. 20, 3, p. 1177-1180 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands

      Petersen, T. P., Ritzén, A. & Ulven, Trond, 19 Nov 2009, In: Organic Letters. 11, 22, p. 5134-5137 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      1,2-Dihydrospiro[carbazole-3(4H),2'-[1,3]dioxolane]

      Bjerrum, J. V., Ulven, Trond & Bond, A., 2009, In: Acta Crystallographica. Section E: Structure Reports Online. 65, p. o579

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      4-Fluoro-N-methyl-N-(1,2,3,4-tetrahydrocarbazol-3-yl)benzenesulfonamide

      Rasmussen, K. G., Ulven, Trond & Bond, A., 2009, In: Acta Crystallographica. Section E: Structure Reports Online. 65, p. o742

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Cyclopropyl and cyclobutyl epothilone analogs

      Nicolaou, K. C., Namoto, K., Ritzén, A., Ulven, Trond, Shoji, M. & Altmann, K., 2009, Patent No. EP 1,420,780 B1

      Research output: Patent

    18. Published

      Discovery and structure-activity relationship investigations of 4-arylethynyldihydrocinnamic acid agonists of the antidiabetic target free fatty acid receptor 1

      Christiansen, E., Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., Spinrath, A., Bond, A., Drewke, C., Ullrich, S., Kassack, M. U., Kostenis, E. & Ulven, Trond, 2009.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    19. Published

      Ethyl 2-(1,2,3,4-tetrahydrospiro[carbazole-3,2'- [1,3]dioxolan]-9-yl)acetate

      Loffler, P., Ulven, Trond & Bond, A., 2009, In: Acta Crystallographica. Section E: Structure Reports Online. 65, Section E, p. o685

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Extraction of G-quadruplex ligands from disulfide-based dynamic combinatorial libraries

      Nielsen, Mads & Ulven, Trond, 2009, p. ORGN-345.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    21. Published

      Flow chemistry methods for the synthesis chemokine receptor ligands

      Petersen, T. P., Ritzén, A. & Ulven, Trond, 2009, p. ORGN-570.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    22. Published

      The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation

      Schroeder, R., Merten, N., Mathiesen, Jesper M., Martini, L., Letunic, A. K., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, Trond, Drewke, C., Whistler, J., Pardo, L., Gomeza, J. & Kostenis, E., 2009, In: Journal of Biological Chemistry. 284, 2, p. 1324-1336 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 2008
    24. Published

      Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes

      Ulven, Elisabeth Rexen, Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., Spinrath, A., Bond, A. D., Drewke, C., Ullrich, S., Kassack, M. U., Kostenis, E. & Ulven, Trond, 27 Nov 2008, In: Journal of Medicinal Chemistry. 51, 22, p. 7061-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding

      Jensen, P. C., Thiele, S., Ulven, Trond, Schwartz, Thue W. & Rosenkilde, Mette, 17 Jun 2008, In: Journal of Biological Chemistry. 283, 34, p. 23121-23128 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Selective extraction of G-quadruplex ligands from a rationally designed scaffold-based dynamic combinatorial library

      Nielsen, M. C. & Ulven, Trond, 1 Jan 2008, In: Chemistry: A European Journal. 14, 31, p. 9487-9490 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2007
    28. Published

      A novel antagonist of CRTH2 blocks eosinophil release from bone marrow, chemotaxis and respiratory burst

      Royer, J. F., Schratl, P., Lorenz, S., Kostenis, E., Ulven, Trond, Schuligoi, R., Peskar, B. A. & Heinemann, A., 1 Dec 2007, In: Allergy. 62, 12, p. 1401-1409 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D2 receptor CRTH2

      Ulven, Trond, Gallen, M. J., Nielsen, M. C., Merten, N., Schmidt, C., Mohr, K., Tränkle, C. & Kostenis, E., 1 Nov 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 21, p. 5924-5927 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking

      Schratl, P., Royer, J. F., Kostenis, E., Ulven, Trond, Sturm, E. M., Waldhoer, M., Hoefler, G., Schuligoi, R., Lippe, I. T., Peskar, B. A. & Heinemann, A., 1 Oct 2007, In: Journal of Immunology. 179, 7, p. 4792-4799 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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