A concise synthesis of the potent inflammatory mediator 5-oxo-ETE
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A concise synthesis of the potent inflammatory mediator 5-oxo-ETE. / Tyagi, Rahul; Shimpukade, Bharat; Blättermann, Stefanie; Kostenis, Evi; Ulven, Trond.
In: MedChemComm, Vol. 3, 2012, p. 195-198.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A concise synthesis of the potent inflammatory mediator 5-oxo-ETE
AU - Tyagi, Rahul
AU - Shimpukade, Bharat
AU - Blättermann, Stefanie
AU - Kostenis, Evi
AU - Ulven, Trond
PY - 2012
Y1 - 2012
N2 - A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions
AB - A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions
KW - inflammatory mediator
KW - 5-oxo-ETE
M3 - Journal article
VL - 3
SP - 195
EP - 198
JO - MedChemComm
JF - MedChemComm
SN - 2040-2503
ER -
ID: 189158850