An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH. / Marcher-Rørsted, Emil; Nykodemova, Jitka; Kristensen, Jesper Langgaard.

In: SynOpen, Vol. 5, No. 2, 2021, p. 158-160.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Marcher-Rørsted, E, Nykodemova, J & Kristensen, JL 2021, 'An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH', SynOpen, vol. 5, no. 2, pp. 158-160. https://doi.org/10.1055/a-1524-4439

APA

Marcher-Rørsted, E., Nykodemova, J., & Kristensen, J. L. (2021). An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH. SynOpen, 5(2), 158-160. https://doi.org/10.1055/a-1524-4439

Vancouver

Marcher-Rørsted E, Nykodemova J, Kristensen JL. An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH. SynOpen. 2021;5(2):158-160. https://doi.org/10.1055/a-1524-4439

Author

Marcher-Rørsted, Emil ; Nykodemova, Jitka ; Kristensen, Jesper Langgaard. / An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH. In: SynOpen. 2021 ; Vol. 5, No. 2. pp. 158-160.

Bibtex

@article{c0ef7740c8f243d4957f30859dc078c8,
title = "An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH",
abstract = "4-{2-[(2-hydroxybenzyl)amino]ethyl}-2,5-dimethoxybenzo­nitrile (25CN-NBOH) was first reported as a potent and highly selective serotonin 2A receptor (5-HT2AR) agonist in 2014. The compound has since found extensive use as a pharmacological tool in a variety of in vivo and in vitro studies. In the present study, we present an improved and scalable synthesis of 25CN-NBOH making this compound readily available to the scientific community.",
author = "Emil Marcher-R{\o}rsted and Jitka Nykodemova and Kristensen, {Jesper Langgaard}",
year = "2021",
doi = "10.1055/a-1524-4439",
language = "English",
volume = "5",
pages = "158--160",
journal = "SynOpen",
issn = "2509-9396",
publisher = "Thieme Medical Publishers",
number = "2",

}

RIS

TY - JOUR

T1 - An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH

AU - Marcher-Rørsted, Emil

AU - Nykodemova, Jitka

AU - Kristensen, Jesper Langgaard

PY - 2021

Y1 - 2021

N2 - 4-{2-[(2-hydroxybenzyl)amino]ethyl}-2,5-dimethoxybenzo­nitrile (25CN-NBOH) was first reported as a potent and highly selective serotonin 2A receptor (5-HT2AR) agonist in 2014. The compound has since found extensive use as a pharmacological tool in a variety of in vivo and in vitro studies. In the present study, we present an improved and scalable synthesis of 25CN-NBOH making this compound readily available to the scientific community.

AB - 4-{2-[(2-hydroxybenzyl)amino]ethyl}-2,5-dimethoxybenzo­nitrile (25CN-NBOH) was first reported as a potent and highly selective serotonin 2A receptor (5-HT2AR) agonist in 2014. The compound has since found extensive use as a pharmacological tool in a variety of in vivo and in vitro studies. In the present study, we present an improved and scalable synthesis of 25CN-NBOH making this compound readily available to the scientific community.

U2 - 10.1055/a-1524-4439

DO - 10.1055/a-1524-4439

M3 - Journal article

VL - 5

SP - 158

EP - 160

JO - SynOpen

JF - SynOpen

SN - 2509-9396

IS - 2

ER -

ID: 272425188