(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-. / Frydenvang, Karla; Enna, Sam J.; Krogsgaard-Larsen, Povl.

In: Acta Crystallographica Section C: Crystal Structure Communications, Vol. 53, No. 8, 15.08.1997, p. 1088-1091.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Frydenvang, K, Enna, SJ & Krogsgaard-Larsen, P 1997, '(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-', Acta Crystallographica Section C: Crystal Structure Communications, vol. 53, no. 8, pp. 1088-1091. https://doi.org/10.1107/S0108270197004290

APA

Frydenvang, K., Enna, S. J., & Krogsgaard-Larsen, P. (1997). (-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-. Acta Crystallographica Section C: Crystal Structure Communications, 53(8), 1088-1091. https://doi.org/10.1107/S0108270197004290

Vancouver

Frydenvang K, Enna SJ, Krogsgaard-Larsen P. (-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-. Acta Crystallographica Section C: Crystal Structure Communications. 1997 Aug 15;53(8):1088-1091. https://doi.org/10.1107/S0108270197004290

Author

Frydenvang, Karla ; Enna, Sam J. ; Krogsgaard-Larsen, Povl. / (-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-. In: Acta Crystallographica Section C: Crystal Structure Communications. 1997 ; Vol. 53, No. 8. pp. 1088-1091.

Bibtex

@article{3eb95662f16048bd86c1deada625b1e9,
title = "(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-",
abstract = "One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABAB receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the R configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing, hydrogen bonds are observed between the ammonium group and the chloride ions.",
author = "Karla Frydenvang and Enna, {Sam J.} and Povl Krogsgaard-Larsen",
year = "1997",
month = aug,
day = "15",
doi = "10.1107/S0108270197004290",
language = "English",
volume = "53",
pages = "1088--1091",
journal = "Acta crystallographica. Section C, Structural chemistry",
issn = "2053-2296",
publisher = "Wiley",
number = "8",

}

RIS

TY - JOUR

T1 - (-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-

AU - Frydenvang, Karla

AU - Enna, Sam J.

AU - Krogsgaard-Larsen, Povl

PY - 1997/8/15

Y1 - 1997/8/15

N2 - One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABAB receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the R configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing, hydrogen bonds are observed between the ammonium group and the chloride ions.

AB - One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABAB receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the R configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing, hydrogen bonds are observed between the ammonium group and the chloride ions.

UR - http://www.scopus.com/inward/record.url?scp=0031213330&partnerID=8YFLogxK

U2 - 10.1107/S0108270197004290

DO - 10.1107/S0108270197004290

M3 - Journal article

AN - SCOPUS:0031213330

VL - 53

SP - 1088

EP - 1091

JO - Acta crystallographica. Section C, Structural chemistry

JF - Acta crystallographica. Section C, Structural chemistry

SN - 2053-2296

IS - 8

ER -

ID: 382748111