(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-
Research output: Contribution to journal › Journal article › Research › peer-review
One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABAB receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the R configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing, hydrogen bonds are observed between the ammonium group and the chloride ions.
Original language | English |
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Journal | Acta Crystallographica Section C: Crystal Structure Communications |
Volume | 53 |
Issue number | 8 |
Pages (from-to) | 1088-1091 |
Number of pages | 4 |
ISSN | 0108-2701 |
DOIs | |
Publication status | Published - 15 Aug 1997 |
ID: 382748111